Premier League Odds & Predictions Matchweek 16: EPL Expert Picks

My Premier League odds and predictions for Matchweek 16 feature updated odds for every match, along with three moneyline plays and a player prop. 

I'm backing a Chelsea side with an ideal bounce-back opportunity, along with two teams playing in enemy environments. Meanwhile, Erling Haaland looks to continue his momentum from midweek in Madrid. 

💰 Premier League predictions: Matchweek 16

Here are my Premier League predictions for Matchweek 16. Premier League odds are live and updated in real time.

🔢 Premier League odds: Matchweek 16

Live Premier League odds for every Matchweek 16 game; updated in real time.

📊 Chelsea vs. Everton odds

• Date: Saturday, Dec. 13
• Kickoff: 10 a.m. ET
• Location: Stamford Bridge (London)
• How to watch: USA Network

🔮 Chelsea vs. Everton prediction: Chelsea ML (-145) ⭐⭐⭐

Saturday's match at Stamford Bridge offers a perfect bounce-back opportunity for the home betting favorite. Chelsea has no wins in four matches, but plays an Everton team that has fits in West London. 

Everton hasn't won at Stamford Bridge in 15 attempts, a dubious record dating back to 2011. The Toffees have lost 11 and tied four in that abject run. Everton has been playing well on the road, having picked up consecutive wins, but this matchup does not suit David Moyes' men. 

FanDuel offers the best odds of the best sports betting apps (-145), where a winning $10 bet will profit $6.90. It's a 3-star pick due to the short odds. 

📊 Liverpool vs. Brighton odds

• Date: Saturday, Dec. 13
• Kickoff: 10 a.m. ET
• Location: Anfield (Liverpool)
• How to watch: Peacock

📊 Burnley vs. Fulham odds

• Date: Saturday, Dec. 13
• Kickoff: 12:30 p.m. ET
• Location: Turf Moor (Burnley)
• How to watch: NBC

📊 Arsenal vs. Wolves odds

• Date: Saturday, Dec. 13
• Kickoff: 3 p.m. ET
• Location: Emirates Stadium (Liverpool)
• How to watch: USA Network

📊 Crystal Palace vs. Man City odds

• Date: Sunday, Dec. 14
• Kickoff: 9 a.m. ET
• Location: Selhurst Park (London)
• How to watch: Peacock

🔮 Crystal Palace vs. Man City prediction: Man City ML (-115) ⭐⭐⭐⭐

Selhurst Park offers one of the more inhospitable environments for visiting teams. Despite the advantage of the 12th man, Crystal Palace has won only two of seven home matches, with four draws and a loss.

They lost and tied the previous two at home and face a Man City side that is rolling. Pep Guardiola's team has won five of the previous six in the Premier League, including the last three.

Its 2-1 midweek win over Real Madrid in the Champions League will provide the feel-good vibes City will need to eke out a road victory. With Arsenal's loss last week to Aston Villa, the door is wide open for a City team that often turns things on around the holidays. 

When the pressure is on, there is no team I'd rather back. Of the best sports betting sites, BetMGM and DraftKings provide the best odds (-115). Those odds imply a 53.49%, and a winning $10 bet will profit $8.70. 

🔮 Crystal Palace vs. Man City prediction: Erling Haaland anytime goal (-125) ⭐⭐⭐⭐

It's only one goal in the last four Premier League matches for Haaland. However, he scored midweek in the Champions League and has 15 goals in as many Premier League matches. 

He has played against Crystal Palace four times in the top flight, and he scored in every game. Haaland scored six goals against them, and he'll be amped to make it seven. The Norwegian has six goals in seven away matches. 

The odds for him to score range from -125 to -140, with bet365 providing the best value. A winning $10 bet at bet365 will line your pockets with an $8 profit. 

📊 Sunderland vs. Newcastle odds

• Date: Sunday, Dec. 14
• Kickoff: 9 a.m. ET
• Location: Stadium of Light (Sunderland)
• How to watch: USA Network

📊 Nottingham Forest vs. Tottenham odds

• Date: Sunday, Dec. 14
• Kickoff: 9 a.m. ET
• Location: City Ground (Nottingham)
• How to watch: Peacock

📊 West Ham vs. Aston Villa

• Date: Sunday, Dec. 14
• Kickoff: 9 a.m. ET
• Location: London Stadium (London)
• How to watch: Peacock

🔮 West Ham vs. Aston Villa prediction: Aston Villa ML (+105) ⭐⭐⭐⭐

Aston Villa is flying, having won eight in a row in all competitions, including against league leaders Arsenal at home in Matchweek 15.

The Villains have won three of the previous four Premier League matches on the road. Unai Emery's team has the sixth-best record on enemy turf, with just two losses in seven matches. 

West Ham, meanwhile, has the second-worst home record, having taken six points from a possible 21. The Hammers won two of the previous three matches at London Stadium.

However, the resurgence under Nuno Espírito Santo has stalled recently, with just one win in the last five matches. I love the plus-money odds DraftKings offers (+105), where a winning $10 bet will profit $10.50.  

Brentford vs. Leeds United odds

• Date: Sunday, Dec. 14
• Kickoff: 1130 a.m. ET
• Location: Gtech Stadium (London)
• How to watch: USA Network

📊 Manchester United vs. Bournemouth odds

• Date: Monday, Dec. 15
• Kickoff: 3 p.m. ET
• Location: Old Trafford (Manchester)
• How to watch: USA Network