Premier League Odds & Predictions Matchweek 10: Best Bets This Week

We're already a quarter of the way through the 2025-26 season as I provide the updated Premier League odds for every Matchweek 10 game, along with three predictions.

The soccer picks below feature Arsenal, Fulham, and Brighton, expecting the Gunners to increase their lead atop the Premier League thanks to another clean sheet. 

💰 Premier League predictions: Matchweek 10

Here are my Premier League predictions for Matchweek 10. Premier League odds are live and updated in real time.

🔢 Premier League odds: Matchweek 10

Live Premier League odds for every Matchweek 10 game; updated in real time.

📊 Crystal Palace vs. Brentford odds

• Date: Saturday, Nov. 1
• Kickoff: 11 a.m. ET
• Location: Selhurst Park (London)
• How to watch: Peacock

📊 Nottingham Forest vs. Manchester United odds

• Date: Saturday, Nov. 1
• Kickoff: 11 a.m. ET
• Location: City Ground (Nottingham)
• How to watch: Peacock

📊 Burnley vs. Arsenal odds

• Date: Saturday, Nov. 1
• Kickoff: 11 a.m. ET
• Location: Turf Moor (Burnley)
• How to watch: USA Network

🔮 Burnley vs. Arsenal prediction: Arsenal ML & Burnley not to score (-115) ⭐⭐⭐⭐

Arsenal's only away defeat came at Anfield against a Liverpool side that rarely loses at home. The Gunners have allowed two goals in four away matches, conceding one at Liverpool and the other against Newcastle at St James' Park. Mikel Arteta's side has kept a clean sheet in six matches in all competitions, including three in the Premier League. 

Burnley has made a solid account of itself thus far in its return to the Premier League but faces an altogether stiffer challenge against the Premier League odds favorite. Against Tottenham, Man City, and Liverpool - three top-tier Premier League sides - Burnley was outscored 9-1. 

I expect a workmanlike and professional 2-0 win from Arsenal. Of the best sports betting sites, BetMGM offers the best odds (-115), where a winning $10 bet will profit $8.70. 

📊 Brighton vs. Leeds United odds

• Date: Saturday, Nov. 1
• Kickoff: 11 a.m. ET
• Location: American Express Stadium (Brighton and Hove)
• How to watch: Peacock

🔮 Brighton vs. Leeds prediction: Brighton ML (-115) ⭐⭐⭐⭐

Unbeaten in four matches at home, Brighton is a different animal at American Express Stadium. Excluding a disappointing draw against Fulham in the home opener, Brighton has been excellent on the south coast. They beat Manchester City and Newcastle at home and tied Tottenham after throwing away a two-goal lead in the second half. 

The Seagulls welcome a Leeds side that has one win in four away outings, which came against last-place Wolves. They were outscored 8-0 in their other three away matches, including a woeful 0-2 defeat at Turf Moor against fellow relegation favorite Burnley.  

DraftKings has the best price for this pick, with -115 odds. BetMGM, FanDuel, and Caesars offer -120 at the low end of the market. A winning $10 bet at the -115 odds will profit $8.70. 

📊 Fulham vs. Wolves odds

• Date: Saturday, Nov. 1
• Kickoff: 11 a.m ET
• Location: Craven Cottage (London)
• How to watch: Peacock

🔮 Fulham vs. Wolves prediction: Fulham ML (-115) ⭐⭐⭐⭐

While Wolves has been better recently, they enter proceedings at Craven Cottage with a winless away record through four matches. Their only away point came at Tottenham in a 1-1 draw.

Otherwise, the league's bottom-feeders have been outscored 4-0 on enemy turf, including a 2-0 setback at the Stadium of Light against fellow relegation favorites Sunderland. 

Fulham won two of the last three at home, with the only defeat against Arsenal. They only lost that match 1-0 and had a few chances to surprise the Premier League leaders. DraftKings offers the best price (-115), carrying an implied probability of 53.49%. A winning $10 bet will profit $8.70. 

📊 Tottenham vs. Chelsea odds

• Date: Saturday, Nov. 1
• Kickoff: 1:30 p.m. ET
• Location: Tottenham Hotspur Stadium (London)
• How to watch: Peacock

📊 Liverpool vs. Aston Villa odds

• Date: Saturday, Nov. 1
• Kickoff: 1:30 p.m. ET
• Location: Anfield (Liverpool)
• How to watch: Peacock

📊 West Ham United vs. Newcastle United odds

• Date: Sunday, Oct. Nov. 2
• Kickoff: 9 a.m. ET
• Location: London Stadium (London)
• How to watch: USA Network

📊 Man City vs. Bournemouth odds

• Date: Sunday, Nov. 2
• Kickoff: 11:30 a.m. ET
• Location: Etihad Stadium (Manchester)
• How to watch: USA Network

📊 Sunderland vs. Everton odds

• Date: Monday, Nov. 3
• Kickoff: 3 p.m. ET
• Location: Stadium of Light (Sunderland)
• How to watch: USA Network