Arsenal vs. Atletico Madrid Prediction Today: Champions League Odds, Expert Picks & Best Bets

Last Updated: October 21, 2025 1:41 PM EDT • 3 minute read X Social Google News Link

All eyes will be on the Emirates Stadium this afternoon, and my Arsenal vs. Atletico Madrid prediction anticipates a tight back and fourth contest in one of the Champions League’s most anticipated matches of the week.
Arsenal enters as a -165 betting favorite, but this won’t be a straightforward game for the hosts when they face an Atletico Madrid side that’s been famously difficult to play against in the Champions League. My Champions League best bets are predicting both teams scoring, as well as an Atletico Madrid player I expect to shine when the game kicks off at 3 p.m. ET (Paramount+).
Want to make sure SBR shows up often in your Google search results and Discover feed? Simply click here and add Sportsbook Review as one of your "source preferences".
⚽ Arsenal vs. Atletico Madrid predictions
Soccer picks for Tuesday;; odds subject to change.
- Game pick: Draw (+310 via bet365) ⭐⭐⭐
- Over/Under pick: Over 2.5 (-111 via bet365) ⭐⭐⭐⭐
- Player prop pick: Julian Alvarez to score assist (+225 via DraftKings) ⭐⭐⭐
✅ Arsenal vs. Atletico Madrid expert pick
🎉 Both teams to score (-110) ⭐⭐⭐⭐
There might not be a winner this afternoon, but there should be plenty of goals when Arsenal host Atletico Madrid in North London.
Atletico Madrid bounced back from losing in their opening Champions League game to beat Eintracht Frankfurt 5-1 at home. But, after falling at Liverpool 3-2 in September, Atletico face another hugely difficult task in their second trip to England against an Arsenal team that’s off to a perfect start in the league phase of the Champions League.
While it won’t be much of a surprise for Arsenal to score at home, I’m expecting the Spanish visitors to continue their trend of scoring in every game this season by finding the back of the net. The -110 odds carry a 52.38% implied win percentage, and a winning $10 bet at Caesars on both teams scoring will net a profit of $9.10
💰 Best Arsenal vs. Atletico Madrid player prop bet
Our player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
🔥 Julian Alvarez to score or assist (+225) ⭐⭐⭐⭐⭐
Julian Alvarez needs to be at the top of his game if Atletico Madrid is going to have any chance today. Along with backing Atleti to score, I expect Alvarez to play a significant role and finish the game with a goal contribution.
While Atletico have been great at home over the last two months, they've instituted a conservative approach away from the Riyadh Air Metropolitano, resulting in unpredictable displays on the road by Diego Simeone’s typically organized squad.
But what has remained consistent away from home is the team’s ability to score. The best odds of Alvarez scoring or registering an assist are at DraftKings where a winning $10 bet nets a $22.50 profit.
📊 Arsenal vs. Atletico Madrid odds
Champions League odds updated live in real time.
📺 How to watch Arsenal vs. Atletico Madrid
- Date: Tuesday, Oct. 21
- Kickoff: 3 p.m. ET
- Where: Emirates Stadium (London)
- TV: Paramount+
📃 Affiliate disclosure
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.
Not intended for use in MA. Bonuses not applicable in Ontario.
,(21+. Gambling Problem? Call 1-800-GAMBLER)

Gordon Brunt