NFL Odds Week 17: Betting Lines, Spreads & Totals for Every Game

We look at the NFL odds and Week 17 lines & spreads, focusing on the biggest line movements and playoff implications for the season's penultimate week.
Netflix Christmas GameDay cake as we look at the NFL Week 17 odds
Pictured: Netflix Christmas GameDay cake as we look at the NFL Week 17 odds. Photo by Charles LeClaire-Imagn Images
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NFL odds Week 17, 2025

The NFL odds for Week 17 are via bet365.

Game Spread  Moneyline Over/Under
Cowboys vs. Commanders (Christmas) Commanders +3 DAL -170 / WSH +230 51.5
Lions vs. Vikings (Christmas) Vikings +3.5 DET -180 / MIN +150  49
Broncos vs. Chiefs (Christmas) Chiefs +5.5 DEN -230 / KC +190 39.5
Texans vs. Chargers (Saturday) Chargers +1.5 HOU -125 / LAC +105 39.5
Ravens vs. Packers (Saturday) Packers -3 BAL +125 / GB -150 46.5
Cardinals vs. Bengals Bengals -5.5 ARI +195 / CIN -240 51.5
Jaguars vs. Colts Colts +5.5 JAX -240 / IND +195 44.5
Patriots vs. Jets Jets +9.5 NE -550 / NYJ +400 44
Saints vs. Titans Titans +2 NO -130 / TEN +110 39.5
Steelers vs. Browns Browns +4.5 PIT -190 / CLE +160 35.5
Seahawks vs. Panthers Panthers +7.5 SEA -425 / CAR +325 42.5
Buccaneers vs. Dolphins OTB OTB OTB
Giants vs. Raiders Raiders +3 NYG -165 / LV +140 43.5
Eagles vs. Bills Bills -3 PHI +135 / BUF -160 46
Bears vs. 49ers (SNF) 49ers -3 CHI +135 / SF -160 50.5
Rams vs. Falcons (MNF) Falcons +8.5 LAR -500 / ATL +375 48.5

Our NFL picks will be locked and loaded for Week 17 as the NFL playoff elimination watch continues to take shape into the season's penultimate week.

  • We have a trio of games airing on Netflix on Christmas day:
    • The Dallas Cowboys are a 3-point road betting favorite at the Washington Commanders (Northwest Stadium, 1 p.m. ET)
    • The Detroit Lions are a 3.5-point road betting favorite at the Minnesota Vikings (U.S. Bank Stadium, 4:30 p.m. ET)
    • The Denver Broncos are a 5.5-point road betting favorite at the Kansas City Chiefs (GEHA Field at Arrowhead Stadium, 8:15 p.m. ET)
  • A pair of Saturday games also dot the schedule:
    • The Houston Texans are a 1.5-point road betting favorite at the Los Angeles Chargers (SoFi Stadium, 4:30 p.m. ET, NFL Network)
    • The Green Bay Packers are a 5.5-point home betting favorite as they welcome the Baltimore Ravens (Lambeau Field, 8 p.m. ET, Peacock)
  • Sunday's action wraps with the San Francisco 49ers a 3-point home betting favorite over the Chicago Bears per the Sunday Night Football odds (Solider Field, 8:20 p.m. ET, NBC/Peacock)
  • The Monday Night Football odds have the Los Angeles Rams an 8.5-point road betting favorite at the Atlanta Falcons (Mercedes-Benz Stadium, 8:15 p.m. ET, ESPN)

Cowboys vs. Commanders odds: Christmas

  • Kickoff: 1 p.m. ET from Northwest Stadium (Landover, Md.)
  • How to watch: Netflix

Lions vs. Vikings odds: Christmas

  • Kickoff: 4:30 p.m. ET from U.S. Bank Stadium (Minneapolis)
  • How to watch: Netflix

Broncos vs. Chiefs odds: Christmas

  • Kickoff: 8:15 p.m. ET from GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
  • How to watch: Netflix

Texans vs. Chargers odds: Saturday

  • Kickoff: 4:30 p.m. ET from SoFi Stadium (Inglewood, Calif.)
  • How to watch: NFL Network

Ravens vs. Packers odds: Saturday

  • Kickoff: 8 p.m. ET from Lambeau Field (Green Bay, Wis.)
  • How to watch: Peacock

Bears vs. 49ers odds: Sunday Night Football

  • Kickoff: 8:20 p.m. ET from Levi's Stadium (Santa Clara, Calif.)
  • How to watch: NBC/Peacock

Rams vs. Falcons odds: Monday Night Football

  • Kickoff: 8:15 p.m. ET from Mercedes-Benz Stadium (Atlanta)
  • How to watch: ESPN

NFL Week 17 odds and lines

There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your picks, the harder it becomes to identify edges and secure the best price on most sides or totals.

Who's playing on prime time in Week 17?

We have a whopping seven "prime time" games in Week 17. Three Christmas Day games: Cowboys vs. Commanders (1 p.m. ET), Lions vs. Vikings (4:30 p.m. ET), and Broncos vs. Chiefs (8:15 p.m. ET). Two Saturday games: Texans vs. Chargers (4:30 p.m. ET) and Ravens vs. Packers (8 p.m. ET). The week ends with our standard affairs: Bears vs. 49ers on Sunday Night Football (8:20 p.m. ET)


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