Vikings vs. Browns Prediction: International Series Opening Odds & Early Picks

Last Updated: September 29, 2025 9:04 AM EDT • 2 minute read X Social Google News Link

The third week of the NFL International Series takes us to London, where the Minnesota Vikings and Cleveland Browns will battle at 9:30 a.m. ET on Sunday (NFL Network).
My Vikings vs. Browns prediction and NFL picks back Minnesota to win and cover as the 3.5-point betting favorite, taking advantage of an inept Cleveland offense that still hasn't scored 20 points.
The game takes place at Tottenham Hotspur Stadium, and the analysis below is part of the NFL predictions for Week 5.
🏈 Early Vikings vs. Browns prediction & best bet
Stay ahead with the rest of our early NFL predictions for Week 5.
Vikings -3.5 (-110) ⭐⭐⭐⭐
Backing the Vikings to win by four points or more boils down to my complete lack of confidence in the Browns' offense. Kevin Stefanski's team is averaging 14 points per game - the second-fewest in football (Tennessee averages 12.8).
That paltry average has come against the shoddy defense of the Cincinnati Bengals (20th-ranked defensive DVOA) and the Detroit Lions' mediocre 16th-ranked unit.
If Joe Flacco has trouble scoring against those defenses, how will he be productive against a Minnesota Vikings unit that had the second-best defensive DVOA entering Week 4?
While I don't have a ton of confidence in the Vikings' offensive inconsistencies, at least it has proven that, with presumed starter Carson Wentz under center, it can put points on the board.
He put 15 fourth-quarter points on the board against Pittsburgh in Dublin and scored 48 against the Bengals. Before you chuckle uncontrollably, remember the Browns managed just 16 against Trey Hendrickson and Co.
Wentz has the added benefit of being at the helm of the fifth-best offensive rushing DVOA.
Four of the five best sports betting sites offer -3.5, three of which - bet365, BetMGM, and Caesars - at the standard juice of -110. A winning $10 bet will yield a profit of $9.09.
📺️ How to watch International Series
Matchup: Sunday, Oct. 5
When: 9:30 a.m. ET
Where: Tottenham Hotspur Stadium (London)
TV: NFL Network
📊 Vikings vs. Browns odds: International Series
Latest NFL odds updated live in real time.
📈 Vikings vs. Browns opening odds
- Moneyline: Vikings -325 | Browns +260
- Spread: Vikings -6.5 (-120) | Browns +6.5 (+100)
- Over/Under: Over 41.5 (-110) | Under 41.5 (-110)
💡 Vikings vs. Browns odds analysis
DraftKings is the only one of the best sports betting apps offering a 4.5-point spread. The four sportsbooks offering a -3.5 have odds ranging from -110 to -115. I can see the spread increasing to 4, possibly 4.5 points, and I wouldn't back the Vikings any higher than -4.
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Gary Pearson X social