Titans vs. 49ers Player Props Today: Best Bets & TD Picks for NFL Week 15
Last Updated: December 14, 2025 9:45 AM EST • 3 minute read X Social Google News Link
My Titans vs. 49ers player props envision this matchup as a playground for Brock Purdy. With San Francisco sitting as an afterthought in a loaded NFC West, the Niners should reinforce their status as divisional contenders with a convincing performance offensively.
The action for Titans vs. 49ers kicks off from Levi’s Stadium in Santa Clara, Calif., today at 4:25 p.m. ET (FOX). The 49ers are 12.5-point betting favorites as part of our NFL Week 15 predictions.
🏈 Titans vs. 49ers player prop bets
See the latest NFL odds and our experts' NFL picks for every game this season.
| Player | Prop bet | Best odds | Confidence |
|---|---|---|---|
| Brock Purdy, QB, 49ers | Over 240.5 passing yards | -115 via BetMGM | ⭐⭐⭐⭐ |
| Elic Ayomanor, WR, Titans | 4+ receptions | +160 via DraftKings | ⭐⭐⭐⭐ |
| Brian Robinson Jr., RB, 49ers | Score a touchdown | +350 via DraftKings | ⭐⭐⭐⭐ |
💰 Titans vs. 49ers best bet
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Brock Purdy Over 240.5 passing yards (-115) ⭐⭐⭐⭐
Tennessee ranks 23rd in pass defense, allowing 228.5 passing yards per game. The Titans have been especially generous through the air lately, permitting a 364-yard effort from Shedeur Sanders in their last game.
Christian McCaffrey hasn’t been especially efficient on the ground, so we like the 49ers to do their damage passing. Brock Purdy’s muted efforts since returning from injury keep this passing prop in a favorable range ahead of a juicy matchup.
BetMGM offers the line at 240.5 passing yards with -115 odds on Over, equating to an implied probability of 53.49%. A winning $10 wager would profit $8.70.
🔥 More Titans vs. 49ers prop picks
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Elic Ayomanor 4+ receptions (+160) ⭐⭐⭐⭐
The San Francisco secondary does a decent job of preventing opposing wideouts from logging chunk play gains, but the 49ers have allowed volume in terms of receptions. San Francisco has surrendered 12.7 receptions per game to the wide receiver position, the fourth-most in the NFL.
The Tennessee passing offense hasn’t been able to sustain much volume, but Elic Ayomanor could present solid value with +160 odds from DraftKings on 4+ receptions. The implied probability for the prop is 38.5%. Ayomanor has logged five-plus targets in 10 of 12 games played.
A winning $10 wager on this prop would profit $16.
Brian Robinson Jr. to score a touchdown (+350) ⭐⭐⭐⭐
In a game that could get out of hand, I’m leaning into Brian Robinson Jr. being given an opportunity to take advantage of Tennessee’s poor goal-line run defense.
The Titans have allowed 14 rushing scores to running backs this season, tied for third-most in the NFL. While McCaffrey’s anytime TD scorer odds are uninspiring at -325, we can score Robinson’s prop at +350 from BetMGM.
Robinson has found the end zone in two of his past five games and has drawn at least seven rushing attempts in four straight games, so the involvement has been consistent. The implied probability based on the odds from BetMGM is 22.22%. A winning $10 wager on this prop would profit $35.00.
📺 How to watch Titans vs. 49ers
- Date: Sunday, Dec. 14
- Kickoff: 4:25 p.m. ET
- Location: Levi’s Stadium (Santa Clara, Calif.)
- TV: FOX
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