Seahawks vs. 49ers Predictions & Opening Odds for NFC West Title | NFL Week 18

My Seahawks vs. 49ers predictions break down which team provides the better betting opportunity, with both juggernauts entering Saturday's NFC West showdown on six-game winning streaks. 

The early odds reflect the unmissable parity between teams, with either team the 1 or 1.5-point betting favorite depending on the sportsbook. I'm backing the 49ers on the moneyline, expecting them to continue their electric form since Brock Purdy's return to the lineup. Not only is the NFC West crown on the line, but so too is the NFC's No. 1 seed. Saturday's kickoff from Levi's Stadium in Santa Clara, Calif., is set for 8 p.m. ET (ESPN/ABC). 

🏈 Early Seahawks vs. 49ers prediction

See the latest NFL odds and our experts' NFL picks for every game this season.

49ers ML (-108) ⭐⭐⭐⭐

The resilience this 49ers team has shown is off-the-charts impressive. They're in a position to secure the NFC's No. 1 seed despite having to cope with more early-season injuries than a physiotherapist clinic. 

The 49ers are 6-0 since Brock Purdy's return to the lineup, scoring at least 37 points four times. While they'll have their work cut out against a Seattle team with the league's best defensive DVOA, the 49ers offense is in peak form.

Purdy has accounted for 13 TDs in the previous three games (11 passing, two rushing) while throwing just two picks.

Sam Darnold, meanwhile, has been a turnover machine recently, tossing four picks in the last four games. As if the 49ers needed more motivation, they won't have to go on the road again this season with a victory, including for the Super Bowl. 

📊 Live Seahawks vs. 49ers odds: Week 18 

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Seahawks vs. 49ers opening odds

• Moneyline: Seahawks -106 | 49ers -110
• Spread: Seahawks +1.5 (-120) | 49ers -1.5 (-102)
• Over/Under: Over 49.5 (-110) | Under 49.5 (-110)

Seahawks vs. 49ers line movement

The odds for this game have just been released, with three of the five best sports betting sites (FanDuel, BetMGM, bet365) pegging the 49ers as the 1.5-point betting favorite. However, Caesars has the Seahawks as the 1-point betting favorite, and DraftKings has them as the 1.5-point betting favorite. This game has every chance of turning into a pick'em.  

📈 Seahawks vs. 49ers trends & betting notes for Saturday prime time

• The 49ers are 10-5-1 ATS, and the Seahawks are 11-5
• The 49ers are 3-3-1 ATS at home
• The Seahawks are 7-1 ATS on the road

📺 How to watch Seahawks vs. 49ers on Saturday 

• Date: Saturday, Jan. 3
• Kickoff: 8 p.m. ET
• Location: Levi's Stadium (Santa Clara, Calif.)
• TV: ABC/ESPN