NFL Predictions Week 8: Best Bets & Odds for Every Game

Last Updated: October 20, 2025 5:00 AM EDT • 4 minute read X Social Google News Link

Our NFL predictions for Week 8 break down every matchup this week with live odds and our best bets for all 13 games from Thursday Night Football to Monday Night Football. Check back throughout the week to read our latest previews and expert picks.
🏈 NFL predictions for Week 8
See all of our NFL picks for every Week 8 game with the latest odds.
- Early Vikings vs. Chargers prediction
- Vikings vs. Chargers prediction (coming soon)
- Vikings vs. Chargers player props (coming soon)
- Vikings vs. Chargers same-game parlay (coming soon)
- Vikings vs. Chargers anytime touchdown scorer predictions (coming soon)
- Vikings vs. Chargers first touchdown scorer predictions (coming soon)
- Vikings vs. Chargers expert picks (coming soon)
- Early Packers vs. Steelers prediction (coming soon)
- Packers vs. Steelers prediction (coming soon)
- Packers vs. Steelers player props (coming soon)
- Packers vs. Steelers same-game parlay (coming soon)
- Packers vs. Steelers anytime touchdown scorer predictions (coming soon)
- Packers vs. Steelers first touchdown scorer predictions (coming soon)
- Packers vs. Steelers expert picks (coming soon)
- Dolphins vs. Falcons player props (coming soon)
- Jets vs. Bengals player props (coming soon)
- Browns vs. Patriots player props (coming soon)
- Giants vs. Eagles player props (coming soon)
- Bills vs. Panthers player props (coming soon)
- Bears vs. Ravens player props (coming soon)
- 49ers vs. Texans player props (coming soon)
- Buccaneers vs. Saints player props (coming soon)
- Cowboys vs. Broncos player props (coming soon)
- Titans vs. Colts player props (coming soon)
- Early Commanders vs. Chiefs prediction (coming soon)
- Commanders vs. Chiefs prediction (coming soon)
- Commanders vs. Chiefs player props (coming soon)
- Commanders vs. Chiefs same-game parlay (coming soon)
- Commanders vs. Chiefs anytime touchdown scorer predictions (coming soon)
- Commanders vs. Chiefs first touchdown scorer predictions (coming soon)
- Commanders vs. Chiefs expert picks (coming soon)
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💰 NFL odds & best bets: Week 8
Live NFL odds for every Week 8 game from our best NFL betting sites.
📊 Vikings vs. Chargers odds
- Date: Thursday, Oct. 23
- Kickoff: 8:15 p.m. ET
- Location: SoFi Stadium (Inglewood, Calif.)
- How to watch: Prime Video
🔮 Early Vikings vs. Chargers prediction
⚡️ Chargers -2.5 (-110)
The Chargers have fallen on hard times, but I still have faith in Justin Herbert and a talented defense that should torment Vikings QB Carson Wentz on a short week of preparation.
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📊 Jets vs. Bengals odds
- Date: Sunday, Oct. 26
- Kickoff: 1 p.m. ET
- Location: Paycor Stadium (Cincinnati)
- How to watch: CBS
🔮 Early Jets vs. Bengals prediction
🐯 Bengals -5.5 (-105)
The Bengals are far from the team we thought they'd be entering the season, but the Jets profile as the worst team in football. I'm done expecting that to change after another embarrassing home loss last week to Carolina.
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📊 Bills vs. Panthers odds
- Date: Sunday, Oct. 26
- Kickoff: 1 p.m. ET
- Location: Bank of America Stadium (Charlotte, N.C.)
- How to watch: CBS
🔮 Early Bills vs. Panthers prediction
🐾 Panthers +7.5 (-115)
The Bills have a knack for playing down to their competition in tough road spots like this one, and I'm starting to buy into the Panthers as a frisky underdog. This feels like too many points for struggling Buffalo.
📊 49ers vs. Texans odds
- Date: Sunday, Oct. 26
- Kickoff: 1 p.m. ET
- Location: NRG Stadium (Houston)
- How to watch: FOX
🔮 Early 49ers vs. Texans prediction
🐂 Texans -1.5 (-105)
San Francisco will likely be a popular bet this week after CMC's explosive showing in Week 7. I don't expect an encore against a ferocious Texans defense, which should cause issues for whomever starts at quarterback for the still-snakebitten 49ers.
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📊 Giants vs. Eagles odds
- Date: Sunday, Oct. 26
- Kickoff: 1 p.m. ET
- Location: Lincoln Financial Field (Philadelphia)
- How to watch: FOX
🔮 Early Giants vs. Eagles prediction
🦅 Eagles -7 (-105)
The Giants blew out the Eagles just two weeks ago on a Thursday night, but I'd be shocked by a repeat performance after the Eagles found their stride in a Week 7 win. New York's epic collapse in Denver could linger into this one, too.
📊 Browns vs. Patriots odds
- Date: Sunday, Oct. 26
- Kickoff: 1 p.m. ET
- Location: Gillette Stadium (Foxborough, Mass.)
- How to watch: CBS
🔮 Early Browns vs. Patriots prediction
🐶 Browns +7 (-110)
Drake Maye is that dude, and the Patriots are stacking wins because of it. I'm still skeptical about laying such a big number against a Browns side with an elite defense and some stability on offense with Dillon Gabriel under center.
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Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.
📊 Bears vs. Ravens odds
- Date: Sunday, Oct. 26
- Kickoff: 1 p.m. ET
- Location: M&T Bank Stadium (Baltimore)
- How to watch: CBS
🔮 Early Bears vs. Ravens prediction
🐦⬛ Ravens -6.5 (-110)
Lamar Jackson should be back for the Ravens, whose defense looked much improved against the Rams before last week's bye. That's enough to have me buying a bounce-back effort in a must-win game for Baltimore.
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📊 Dolphins vs. Falcons odds
- Date: Sunday, Oct. 26
- Kickoff: 1 p.m. ET
- Location: Mercedes-Benz Stadium (Atlanta)
- How to watch: FOX
🔮 Early Dolphins vs. Falcons prediction
🪶 Falcons -7.5 (+100)
The Falcons are either the NFL's worst good team or best bad team after an enigmatic 3-3 start. Either way, they're a heck of a lot better than the Dolphins, who have effectively quit on the season with three months to go.
📊 Buccaneers vs. Saints odds
- Date: Sunday, Oct. 26
- Kickoff: 4:05 p.m. ET
- Location: Caesars Superdome (New Orleans)
- How to watch: FOX
🔮 Early Buccaneers vs. Saints prediction
🧭 Buccaneers -6 (-110)
As much respect as I have for the job Kellen Moore has done in his debut season in New Orleans, the Buccaneers are a legitimate contender in the NFC. If they can return some key playmakers for this divisional tilt, it shouldn't be close.
📊 Cowboys vs. Broncos odds
- Date: Sunday, Oct. 26
- Kickoff: 4:25 p.m. ET
- Location: Empower Field at Mile High (Denver)
- How to watch: CBS
🔮 Early Cowboys vs. Broncos prediction
🐎 Broncos -3 (-110)
The Broncos certainly have a flair for the dramatics, but they continue to find ways to win. This doesn't feel like an equal fight on paper against the entertaining but imminently flawed Cowboys, so I'm surprised it's priced like one when considering home-field advantage.
📊 Titans vs. Colts odds
- Date: Sunday, Oct. 26
- Kickoff: 4:25 p.m. ET
- Location: Lucas Oil Stadium (Indianapolis)
- How to watch: CBS
🔮 Early Titans vs. Colts prediction
⚔️ Titans +14.5 (-118)
If you had the Colts laying more than two touchdowns at any point in 2025, take a bow. I love what I've seen from Shane Steichen's team but not enough to buy into one of the biggest spreads of the year in a divisional rivalry.
📊 Packers vs. Steelers odds
- Date: Sunday, Oct. 26
- Kickoff: 8:20 p.m. ET
- Location: Acrisure Stadium (Pittsburgh)
- How to watch: NBC
🔮 Early Packers vs. Steelers prediction
🧀 Packers -3 (-110)
While the spotlight is on Aaron Rodgers against his former team, the Steelers' defense is quietly one of the worst in the NFL. That's a bad sign against one of the league's most complete teams with a lethal vertical passing game.
📊 Commanders vs. Chiefs odds
- Date: Monday, Oct. 27
- Kickoff: 8:15 p.m. ET
- Location: GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
- How to watch: ESPN
🔮 Early Commanders vs. Chiefs prediction
🔴 Chiefs -6 (-110)
The arrow continues to point up for the Chiefs as they return key pieces around Patrick Mahomes. The opposite is true for the Commanders, who could be without star QB Jayden Daniels for this prime-time clash in D.C.
💡 NFL expert picks for Week 8
Follow all of our NFL expert picks for Week 8 throughout the week.
- NFL picks against the spread Week 8 (coming soon)
- NFL survivor picks Week 8 (coming soon)
- NFL QB clutch player rankings Week 8 (coming soon)
- NFL weather report Week 8 (coming soon)
- NFL upset picks Week 8 (coming soon)
- NFL AI predictions Week 8 (coming soon)
- NFL player props Week 8 (coming soon)
- NFL expert picks Week 8 (coming soon)
- NFL best bets Week 8 (coming soon)
- NFL anytime touchdown scorer predictions Week 8 (coming soon)
- NFL first touchdown scorer predictions Week 8
- NFL anytime touchdown scorer parlay Week 8 (coming soon)
- NFL Sunday same-game parlays Week 8 (coming soon)
- National tight ends day player props (coming soon)
- National tight ends day anytime touchdown scorer predictions (coming soon)
- National tight ends day parlay picks (coming soon)
- NFL moneyline picks Week 8 (coming soon)
- NFL long-shot parlay Week 8 (coming soon)
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