NFL Predictions Week 15: Best Bets & Odds for Every Game This Week

Our NFL predictions for Week 15 feature our best bets and expert picks for all 16 games this week, starting with Falcons vs. Buccaneers on Thursday Night Football. Be sure to bookmark this page as we'll be updating it all week long with our latest ATS predictions, player prop bets, and touchdown picks for every game on the Week 15 schedule.

---

NFL predictions for Week 15

See all of our NFL picks for every Week 15 game with the latest odds.

• Early Falcons vs. Buccaneers prediction
• Falcons vs. Buccaneers prediction
• Falcons vs. Buccaneers player props
• Falcons vs. Buccaneers anytime touchdown scorer predictions
• Falcons vs. Buccaneers first touchdown scorer predictions
• Falcons vs. Buccaneers same-game parlay
• Baker Mayfield player props
• Bijan Robinson player props
• Falcons vs. Buccaneers AI predictions
• Falcons vs. Buccaneers weather report
• Falcons vs. Buccaneers best bets
• Browns vs. Bears player props
• Ravens vs. Bengals player props
• Chargers vs. Chiefs player props
• Early Bills vs. Patriots prediction
• Bills vs. Patriots prediction
• Bills vs. Patriots player props
• Bills vs. Patriots anytime touchdown scorer predictions
• Commanders vs. Giants player props
• Raiders vs. Eagles player props
• Jets vs. Jaguars player props
• Cardinals vs. Texans player props
• Packers vs. Broncos player props
• Lions vs. Rams player props
• Panthers vs. Saints player props
• Titans vs. 49ers player props
• Colts vs. Seahawks player props
• Early Vikings vs. Cowboys prediction
• Vikings vs. Cowboys prediction
• Vikings vs. Cowboys player props
• Vikings vs. Cowboys anytime touchdown scorer predictions
• Vikings vs. Cowboys first touchdown scorer predictions
• Vikings vs. Cowboys same-game parlay
• Vikings vs. Cowboys AI predictions
• Vikings vs. Cowboys best bets
• Early Dolphins vs. Steelers prediction
• Dolphins vs. Steelers prediction
• Dolphins vs. Steelers player props
• Dolphins vs. Steelers anytime touchdown scorer predictions
• Dolphins vs. Steelers first touchdown scorer predictions
• Dolphins vs. Steelers same-game parlay
• Dolphins vs. Steelers AI predictions
• Dolphins vs. Steelers best bets

---

NFL odds & expert picks: Thursday Night Football

See the latest Thursday Night Football odds and our best TNF predictions.

Falcons vs. Buccaneers odds

• Date: Thursday, Dec. 11
• Kickoff: 8:15 p.m. ET
• Location: Raymond James Stadium (Tampa, Fla.)
• TV: Prime Video

Early Falcons vs. Buccaneers prediction

🧭 Buccaneers -4.5 (-115)

Neither of these teams are in their best form, but the Falcons are especially pitiful right now after a 37-9 loss to the Seahawks that eliminated them from the playoffs. Tampa Bay can't afford to lose this game, and I like the Bucs to take care of business at home on a short week.

---

NFL odds & expert picks: Sunday

Live NFL odds for every Week 15 game from our best NFL betting sites.

Raiders vs. Eagles odds

• Date: Sunday, Dec. 14
• Kickoff: 1 p.m. ET
• Location: Lincoln Financial Field (Philadelphia)
• TV: FOX

Early Raiders vs. Eagles prediction

🦅 Eagles -13.5 (-115)

The Raiders' season is over and effectively has been for some time, but they're still hanging around after a close loss to the Broncos. The Eagles have struggled to pull away from teams all season long - expect this one to be another ugly win.

Browns vs. Bears odds

• Date: Sunday, Dec. 14
• Kickoff: 1 p.m. ET
• Location: Soldier Field (Chicago)
• TV: FOX

Early Browns vs. Bears prediction

🐻 Bears -7 (-115)

It's OK to believe in the Bears after they went toe-to-toe with the Packers on Sunday in one of the best games of the week - one that left Chicago on the wrong side of the NFC North race. I'm expecting a strong showing at home this week against the Browns, who have lost two straight against teams in worse form than the Bears.

Ravens vs. Bengals odds

• Date: Sunday, Dec. 14
• Kickoff: 1 p.m. ET
• Location: Paycor Stadium (Cincinnati)
• TV: CBS

Early Ravens vs. Bengals prediction

🐯 Bengals +2.5 (-113)

Friends don't let friends bet on the Ravens - at least not with the way Lamar Jackson is playing after a midseason injury that clearly hasn't worn off. Cincinnati just beat its division rival two weeks ago on the road, so this feels like a real value to back the Bengals as home underdogs.

Commanders vs. Giants odds

• Date: Sunday, Dec. 14
• Kickoff: 1 p.m. ET
• Location: MetLife Stadium (East Rutherford, N.J.)
• TV: FOX

Early Commanders vs. Giants prediction

🗽 Giants -1.5 (-110)

Absolutely nothing went right for the Commanders last week in Jayden Daniels' return to the field - he completed fewer than half his attempts in a 31-0 rout against the Vikings. I don't see things getting much better against a rested Giants team coming off a much-needed bye week.

Bills vs. Patriots odds

• Date: Sunday, Dec. 14
• Kickoff: 1 p.m. ET
• Location: Gillette Stadium (Foxborough, Mass.)
• TV: CBS

Early Bills vs. Patriots prediction

🪖 Patriots +1.5 (-115)

What could be the best matchup of the entire season also features one of the strangest lines - New England has won 10 straight, which includes a road win over Bufflao in Week 5, and Drake Maye is playing at at MVP level. I'll gladly take the points on the likely AFC champions.

Chargers vs. Chiefs odds

• Date: Sunday, Dec. 14
• Kickoff: 1 p.m. ET
• Location: GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
• TV: CBS

Early Chargers vs. Chiefs prediction

⚡️ Chargers +5.5 (-105)

Things are beyond dire for the Chiefs, who grade out well by advanced metrics but can't buy an actual win on the field. Kansas City has played a tough schedule, but Los Angeles presents a tough challenge if Justin Herbert is healthy enough to play. Four of the last seven between these teams have been decided by three points or fewer - give me the points in this one.

Cardinals vs. Texans odds

• Date: Sunday, Dec. 14
• Kickoff: 1 p.m. ET
• Location: NRG Stadium (Houston)
• TV: CBS

Early Cardinals vs. Texans prediction

🌵 Cardinals +7.5 (-110)

I have the utmost respect for how well the Texans have played over the last month across their five-game win streak, but Monday's win over the Chiefs was their first by more than seven points since October. I expect Jacoby Brissett and Co. to keep it close in what should still be a Houston win.

Jets vs. Jaguars odds

• Date: Sunday, Dec. 14
• Kickoff: 1 p.m. ET
• Location: EverBank Stadium (Jacksonville, Fla.)
• TV: CBS

Early Jets vs. Jaguars prediction

🐆 Jaguars -11.5 (-110)

First-year head coach Liam Coen has the Jaguars cruising toward a potential AFC South title amid a four-game win streak, while the Jets are running out of quarterbacks after Tyrod Taylor's injury in Sunday's 24-point loss to Miami. This is a big number, but this game shouldn't be close.

Panthers vs. Saints odds

• Date: Sunday, Dec. 14
• Kickoff: 4:25 p.m. ET
• Location: Caesars Superdome (New Orleans)
• TV: FOX

Early Panthers vs. Saints prediction

⚜️ Saints +2.5 (-105)

It's impossible to know what to expect from either of these NFC South rivals on a weekly basis. That's why I'm happy to take the points with the Saints, who beat the Panthers a few weeks ago and have been a tough out under rookie QB Tyler Shough.

Lions vs. Rams odds

• Date: Sunday, Dec. 14
• Kickoff: 4:25 p.m. ET
• Location: SoFi Stadium (Inglewood, Calif.)
• TV: FOX

Early Lions vs. Rams prediction

🐏 Rams -4.5 (-108)

The Lions saved their season with that win over the Cowboys on a short week, but that one victory doesn't erase the legitimate concerns that had Detroit on the playoff bubble. Meanwhile, the Rams still look like the class of the NFC and should be able to dictate terms on both sides of the ball in this heavyweight clash.

Titans vs. 49ers odds

• Date: Sunday, Dec. 14
• Kickoff: 4:25 p.m. ET
• Location: Levi’s Stadium (Santa Clara, Calif.)
• TV: FOX

Early Titans vs. 49ers prediction

⚔️ Titans +13.5 (-118)

The Titans finally got the monkey off their back after more than two months without a victory, but they've shown flashes during that drought with four losses by 10 or fewer points. The 49ers' defense has improved as of late, but I still expect Cam Ward to make enough plays to keep this close.

Packers vs. Broncos odds

• Date: Sunday, Dec. 14
• Kickoff: 4:25 p.m. ET
• Location: Empower Field at Mile High (Denver)
• TV: CBS

Early Packers vs. Broncos prediction

🐎 Broncos +2.5 (-115)

It feels like the betting market doesn't want to take seriously the run that we've seen from Denver, which hasn't lost since September. Bo Nix will need to have a plan against Green Bay's ferocious pass rush, but I trust the Broncos' defense to win one-on-ones against a big-play reliant Packers offense.

Colts vs. Seahawks odds

• Date: Sunday, Dec. 14
• Kickoff: 4:25 p.m. ET
• Location: Lumen Field (Seattle)
• TV: FOX

Early Colts vs. Seahawks prediction

🟢 Seahawks -10.5 (-104)

Daniels Jones is done for the year after an Achilles injury last week, a move that puts Indianapolis' playoff hopes in serious peril. There may be no worse matchup for Riley Leonard's first NFL start than the Seahawks, who have won their last two games by a combined score of 63-9. I don't have much faith in the Colts surviving a truly horrifying road spot in Seattle.

---

NFL odds & expert picks: Sunday Night Football

See the latest Sunday Night Football odds and our best SNF predictions.

Vikings vs. Cowboys odds

• Date: Sunday, Dec. 14
• Kickoff: 8:20 p.m. ET
• Location: AT&T Stadium (Arlington, Texas)
• TV: NBC

Early Vikings vs. Cowboys prediction

🤠 Cowboys -6.5 (-104)

The Cowboys have looked like a different team since trading for star defensive tackle Quinnen Williams at the deadline, and while the Vikings are coming off a 31-0 blowout win over the Commanders, they lost their last two by a combined score of 49-6. I like Dallas to keep its playoff hopes alive with a convincing win in prime time.

---

NFL odds & expert picks: Monday Night Football

See the latest Monday Night Football odds and our best MNF predictions.

Dolphins vs. Steelers odds

• Date: Monday, Dec. 15
• Kickoff: 8:15 p.m. ET
• Location: Acrisure Stadium (Pittsburgh)
• TV: ESPN

Early Dolphins vs. Steelers prediction

🐬 Dolphins +3.5 (-110)

The Steelers outlasted the Ravens last week in a matchup of deeply flawed teams. That doesn't mean Pittsburgh is free from its own issues that led to three losses in its previous four games. The Dolphins have quietly won four straight and should be able to score points to keep this one close - if not win outright.

---

💡 NFL expert picks for Week 15

Follow all of our NFL analysis for Week 15 throughout the week.

• NFL picks against the spread Week 15 (coming soon)
• NFL survivor picks Week 15 (coming soon)
• NFL AI predictions Week 15 (coming soon)
• NFL weather report Week 15 (coming soon)
• NFL upset picks Week 15 (coming soon)
• NFL player props Week 15 (coming soon)
• NFL best bets Week 15 (coming soon)
• NFL anytime touchdown scorer predictions Week 15 (coming soon)
• NFL first touchdown scorer predictions Week 15 (coming soon)
• NFL 2+ touchdown scorer predictions Week 15 (coming soon)
• NFL anytime touchdown scorer parlay Week 15 (coming soon)

---

📃 Affiliate disclosure

Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)