NFL Picks Against the Spread: ATS Predictions for Every Wild Card Round Game
It's time for the most exciting time of the season as we offer our NFL picks against the spread for Wild Card Weekend, with predictions for all six matchups.
As part of our NFL playoff predictions and wild-card matchups, I've offered analysis of three games, including the Buffalo Bills vs. Jacksonville Jaguars, San Francisco 49ers vs. Philadelphia Eagles, and Houston Texans vs. Pittsburgh Steelers.
🏈 NFL picks against the spread: Wild Card Round ATS predictions
See all of our experts' NFL picks for Wild Card Weekend based on the latest NFL odds; pick confidence based on a 1-to-5-star scale.
| Matchup | Pick | Confidence |
|---|---|---|
| Rams (-10) vs. Panthers | Rams (-10) | ⭐⭐⭐ |
| Packers (-1.5) vs. Bears | Bears (+1.5) | ⭐⭐⭐ |
| Bills (-1.5) vs. Jaguars | Bills (-1.5) | ⭐⭐⭐⭐ |
| 49ers vs. Eagles (-4.5) | 49ers (+4.5) | ⭐⭐⭐⭐ |
| Chargers vs. Patriots (-3.5) | Chargers (+3.5) | ⭐⭐⭐ |
| Texans (-3.5) vs. Steelers | Texans (-3.5) | ⭐⭐⭐⭐ |
💰 Best ATS pick for Wild Card Round
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every Wild Card Weekend game.
49ers (+3.5) vs. Eagles ⭐⭐⭐⭐
The San Francisco 49ers have overcome injuries all season, and while they might not win in Philly, I'm confident in their healthy playmakers keeping it close. Kyle Shanahan's team is 7-2 ATS on the road, and the Eagles are a mediocre 4-4 ATS at home.
San Francisco won six in a row before losing a defensive dogfight at home to the Super Bowl odds favorite Seattle Seahawks. The 49ers are arguably the most resilient team in football, considering how badly their lineup was decimated by injuries early in the season, and I expect them to live up to the billing again.
Four of the five best sports betting sites offer the standard juice of -110, and our Dustin Saracini is also onboard with the pick, which he outlined in his 49ers vs. Eagles predictions.
🔥 More Wild Card Round picks
Bills (-1.5) vs. Jaguars ⭐⭐⭐⭐
The Jacksonville Jaguars enter the playoffs as arguably the league's hottest team. However, they're up against former MVP Josh Allen and, according to DVOA, his fourth-ranked offense.
While the Buffalo Bills' second-worst defensive rush DVOA is concerning, it will be able to plaster over many of its deficiencies against the Jags' 20th-ranked rushing unit. And in the playoffs, especially without the Kansas City Chiefs in the equation, I'm confident in putting my money on Allen and the Superman cape he'll be wearing.
FanDuel has the best price at -106, and our Liam Fox projects a high-scoring affair in his Bills vs. Jaguars predictions.
Texans (-3) vs. Steelers ⭐⭐⭐⭐
While the Houston Texans would have preferred securing the division crown, entering Wild Card Weekend on a 10-game winning streak isn't too shabby.
Their second-ranked defense, per DVOA, will cause fits for Aaron Rodgers and his middling offense, providing an immeasurably sterner challenge than the Baltimore Ravens in Week 18.
Houston's offense has improved, too, scoring at least 38 points in two of the final four games. DraftKings is the only sportsbook offering the Texans at -3, and I'm happy to take the slightly longer -120 odds to secure the key number. Our Sean Tomlinson provides more analysis in his Texans vs. Steelers predictions.
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