Patriots vs. Bills Anytime Touchdown Scorer Predictions for Sunday Night Football

The Buffalo Bills host the New England Patriots for Sunday Night Football at Highmark Stadium in Orchard Park, N.Y., and my Patriots vs. Bills anytime touchdown scorer predictions look to take advantage of the 49.5-point Over/Under with the Bills as the 7.5-point home favorite.

These touchdown scorer predictions for Sunday Night Football complement Mike Spector's Patriots vs. Bills prediction and our NFL picks for Week 5.

💰 Patriots vs. Bills anytime touchdown scorer predictions: Sunday Night Football

Find the best and latest NFL odds on any of your Sunday Night Football anytime touchdown scorer predictions with our NFL player prop odds tool. Pick confidence based on a 1-to-5-star scale:

• Keon Coleman, WR, Bills (+185 via FanDuel) ⭐⭐⭐⭐⭐
• Hunter Henry, TE, Patriots (+230 via FanDuel) ⭐⭐⭐⭐
• Stefon Diggs, WR, Patriots (+270 via DraftKings) ⭐⭐⭐⭐

🚀 Best Sunday Night Football anytime touchdown scorer bets

Here are my favorite Patriots vs. Bills touchdown scorer picks based on the best NFL odds for Sunday Night Football:

Keon Coleman, WR, Bills (+185) ⭐⭐⭐⭐⭐

Keon Coleman scored his only touchdown of the season in Week 1 when he was targeted 11 times while catching eight for 112 yards. He hasn't received anywhere near that workload since, with the Bills cruising to 4-0. But Coleman has caught nine of 11 targets across the past three weeks.

Coleman also leads Bills receivers in snaps played each week. He's in an excellent spot on Sunday Night Football against a Patriots team allowing receivers to catch 70.5% of their targets at a 9.80-yard clip. 

I'm making this anytime touchdown scorer prediction at FanDuel, where a winning $10 bet would return a profit of $18.50, compared to a possible return of $17.50 on the same bet at Caesars.

Our Matt Jacob is expecting a significant passing day for Bills QB Josh Allen with his Patriots vs. Bills player props, as is Brenden Schaeffer in his Patriots vs. Bills parlay picks for Sunday Night Football.

Hunter Henry, TE, Patriots (+230) ⭐⭐⭐⭐

Hunter Henry has logged three touchdowns this season, with two coming in the red zone. While he was targeted just twice in the Patriots' lopsided win over the Carolina Panthers last week, Henry caught eight of a season-high 11 targets the week before in a two-touchdown outing against the Pittsburgh Steelers.

The Bills often play in high-scoring games due to their own prolific offense and opponents needing to pass to keep up. The defense has allowed opposing tight ends to catch 81.8% of their targets.

While that's only nine of 11 targets, resulting in just 67 yards and a single touchdown, Henry is the go-to option in the Patriots' passing game and should exploit some of those weaknesses tonight on prime time. He caught four of eight targets while scoring a touchdown in one game against the rival Bills last year.

Stefon Diggs, WR, Patriots (+270) ⭐⭐⭐⭐

Stefon Diggs played a season-high 63% of the snaps last week, and those increased opportunities led to his best game for New England. He caught six of seven targets for 101 yards, with a long of 33.

The high Over/Under for Sunday Night Football indicates the underdog Patriots should be passing throughout the game at Highmark Stadium. Receivers catch 62.9% of their targets at a 7.02-yard rate against the Bills, and they've combined to score five touchdowns against them through four weeks.

Bet the +270 odds at DraftKings for this anytime touchdown scorer prediction ahead of Sunday Night Football. There's an extra $3.50 in profit to be had from a winning $10 bet, compared to the odds at Caesars.

📊 Bills vs. Patriots anytime TD scorer odds for SNF