Patrick Mahomes Player Props & Odds vs. Commanders: Monday Night Football Prop Bets

My best Patrick Mahomes player props for Monday Night Football target the three-time Super Bowl champion to continue his near-flawless play against a Washington Commanders group that's lost two straight games.

Kickoff from GEHA Field at Arrowhead Stadium is at 8:15 p.m. ET (ESPN). Our Gary Pearson likes Kansas City to win and cover the 11.5-point spread in his Commanders vs. Chiefs prediction.

📊 Patrick Mahomes player props & odds vs. Commanders

💰 Best Patrick Mahomes player prop bets vs. Commanders

See all of our NFL picks based on the latest NFL odds.

⬆️ Patrick Mahomes Over 2.5 passing touchdowns (+127) ⭐⭐⭐⭐

Mahomes has thrown at least three touchdowns in three of his last four games and now faces a disappointing Commanders secondary that's struggling to keep wideouts in front of them.

I expect the NFL MVP odds front-runner to lead Kansas City up and down the field in this matchup and score at will. Don't be surprised if one or more of Mahomes' scores come from outside the red zone, as Washington is allowing an NFL-worst 13 yards per completion.

Among the best sports betting sites, DraftKings has the best odds at +127. A $10 wager could win a $12.70 profit if Mahomes comes through for us. It has an implied probability of 44.05%.

⬇️ Patrick Mahomes Under 24.5 rushing yards (-112) ⭐⭐⭐⭐

On the surface, this seems like a poor line to back the Under, given Mahomes has gone Over this total in five of seven games this season.

But the Chiefs' offense has changed dramatically over the course of the last couple of months after getting key receivers back from injury and suspension. In his last three games, Mahomes has gone from 60 rushing yards to 32 yards to 28 yards a week ago.

I expect his rushing yardage to continue to decrease now that he has his full stable of wideouts at his disposal. And facing a banged-up Commanders team without Jayden Daniels, I don't think he'll need to use his legs to win comfortably tonight.

Head to DraftKings for the best odds on this Mahomes player prop, where a successful $10 bet will earn a $8.93 profit with an implied probability of 52.83%.

⬆️ Patrick Mahomes Over 34.5 pass attempts (-108) ⭐⭐⭐

The Chiefs are built to throw the football, especially with Rashee Rice back in the lineup. And Mahomes has shown that he will continue to sling it, even when leading in the second half of games.

He's gone Over this total in all but two contests in 2025, including attempting 35 passes against the Raiders last week despite leading the entire way en route to a 31-0 blowout.

A $10 wager at FanDuel will net a potential $9.26 profit. The -108 odds translate to an implied probability of 51.92%.

🚀 Best Patrick Mahomes SGP odds vs. Commanders

Our parlay calculator shows the best odds for every market across legal sportsbooks in your area.

📺 How to watch Commanders vs. Chiefs: Monday Night Football

• Date: Monday, Oct. 27
• Kickoff: 8:15 p.m. ET
• Where: GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
• TV: ESPN