Rams vs. Panthers Predictions for Wild Card Round | Opening Odds & NFL Playoffs Best Bet
Last Updated: January 6, 2026 3:15 PM EST • 3 minute read X Social Google News Link
The NFL Playoffs begin Saturday as the Los Angeles Rams visit the Carolina Panthers in the Wild Card Round. Carolina pulled off an upset victory when these teams clashed in the regular season, but my Rams vs. Panthers predictions for this wild-card game expect the visitors to roll in the postseason rematch.
The Rams are a 10-point betting favorite and are a far more battle-tested squad. My NFL playoff predictions and wild-card matchups dig into whether they can cover the largest spread of the opening round when the action from Bank of America Stadium in Charlotte, N.C., gets underway at 4:30 p.m. ET (FOX).
🏈 Early Rams vs. Panthers prediction
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Rams -10 (-108) ⭐⭐⭐⭐
The Panthers stumbled into the playoffs, losing three of four. And while they were competitive in two of those three defeats, I don't give that much credence, considering the lackluster quality of opponents. Tampa Bay and New Orleans aren't exactly world beaters, nor are they in the same stratosphere as the Rams.
The game will be Bryce Young's first in the postseason, and I'm not convinced he'll be able to keep up with MVP odds favorite Matthew Stafford and the Rams' league-best offense. The Rams scored the most points per game (30.5), are ranked first in DVOA, and have the second-shortest Super Bowl odds.
While the Panthers' Week 13 upset victory over the Rams was impressive, I don't foresee them repeating that 31-point performance. Since that eyebrow-raising result, the Panthers' offense has sputtered, averaging just 16 points in the final four games.
The Rams, conversely, averaged 36.8 points per game in their final five games.
💡 More NFL predictions
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📊 Live Rams vs. Panthers odds: Wild Card Round
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Our NFL wild-card betting odds provide the updated odds from the best sports betting sites for Rams vs. Panthers.
Rams vs. Panthers opening odds
- Moneyline: Rams -625 | Panthers +350
- Spread: Rams -10.5 (-102) | Panthers +10.5 (-120)
- Over/Under: Over 46.5 (-110) | Under 46.5 (-110)
Rams vs. Panthers line movement
FanDuel is the outlier here, offering the Panthers at +10.5 (-120), but those odds suggest the hook could fall off and that it might join the rest of the best sports betting apps at 10 points before long. This line had moved to 9.5 on Monday across the board before jumping back to double-digits by Tuesday.
The total has held firm since the opener.
📈 Rams vs. Panthers trends & betting notes: Wild Card Round
- Saturday's game will be the Panthers' first playoff game in nine years
- The Rams have won three of the previous four wild-card games, winning by an average of 17 points
📺 How to watch Rams vs. Panthers: Wild Card Round
- Date: Saturday, Jan. 10
- Kickoff: 4:30 p.m. ET
- Location: Bank of America Stadium (Charlotte, N.C.)
- TV: FOX
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