Packers vs. Lions Anytime Touchdown Scorer Predictions: Thanksgiving TD Picks

My Packers vs. Lions anytime touchdown scorer predictions for the Thanksgiving clash feature Josh Jacobs, Amon-Ra St. Brown, and Christian Watson. 

The Lions are the 2.5-point betting favorite, with the game coming from Ford Field in Detroit (1 p.m. ET, FOX). St. Brown has been a consistent scorer on home turf, Watson is quickly becoming one of Jordan Love's preferred targets, and perennial threat Jacobs will play after missing last week. The picks below are part of our NFL Thanksgiving predictions.

✅ Anytime touchdown scorer predictions: Packers vs. Lions

See all of our experts' NFL picks for Week 13.

💰 Best Thanksgiving anytime touchdown scorer bets

🔥 Josh Jacobs, RB, Packers (-120) ⭐⭐⭐⭐

Jacobs will feature in the Thanksgiving clash. With that in mind, I'm backing him to hit the end zone for the ninth time in 11 games this season. 

He hit pay dirt in six of the seven games before missing last week's home encounter against the Minnesota Vikings. He has 11 TDs thus far and is an ever-present threat, particularly in the red zone, where all of his TDs have come. 

FanDuel offers the best odds on this prop. Its -120 odds imply a 54.55% probability, and a winning $10 bet will profit $8.33. 

🔥 Amon-Ra St. Brown, WR, Lions (+105) ⭐⭐⭐⭐

St. Brown has a touchdown in three of the previous five games while scoring in four of five games at Ford Field. With the Packers likely focusing on preventing Jahmyr Gibbs from having another monstrous performance, which I covered in my Packers vs. Lions prediction, St. Brown represents a high-probability option to punch it in. 

Speaking of probabilities, the +105 odds at BetMGM, FanDuel, and bet365 imply a 48.78% likelihood. Those odds are the best value at the best sports betting sites, where a winning $10 bet will profit $10.50. 

Liam Fox's Thanksgiving player props expect a big day for teammate Jahmyr Gibbs.

🔥 Christian Watson, WR, Packers (+215) ⭐⭐⭐

Watson has been much more productive recently than Romeo Doubs, turning into a preferred option for Love.

He scored two TDs in the last away game against the New York Giants and is facing a Lions' defense that has allowed 21 TD passes, tied for the seventh most. If Watson finds the end zone, you'll earn a $21.50 profit on a $10 bet. DraftKings' +215 odds imply a 31.75% likelihood.

📊 Anytime touchdown scorer odds: Packers vs. Lions

See live NFL odds for every game this season.

📺 How to watch Packers vs. Lions: Thanksgiving 2025

• Date: Thursday, Nov. 27
• Kickoff: 1 p.m. ET
• Location: Ford Field (Detroit)
• TV: FOX