NFC Division Winner Picks: Can Trey Lance Keep San Francisco On Top of the West?

Take a look at our best bets to win each division in the NFC for the 2022 NFL season.

Last updated: September 15, 2022 9:16 AM EDT • 4 min read

Only four teams can call themselves NFC divisional champions at the end of the 2022 NFL season, but which four will it be? Find out with our NFC Division Winner picks.

As Week 1 of the 2022 NFL season approaches, teams have their sights set on the Super Bowl. Eight teams' campaigns will end with a divisional championship, with four of those coming from the NFC.

Many of the NFC favorites expectedly have the best shot at winning their respective divisions, and at least three of them offer better value now than they will once the season begins. Act sooner rather than later.

Here are our picks and predictions to win each division in the NFC for the 2022 NFL season (odds via BetMGM and DraftKings Sportsbook).

NFC Division Winner Odds

Market	DraftKings	FanDuel	BetMGM
Eagles to win NFC East	+150	+145	+150
Packers to win NFC North	-190	-155	-154
Buccaneers to win NFC South	-250	-270	-270
Rams to win NFC West	+130	+125	+125

NFC Division Winner Picks

NFC Division Winner Predictions

Philadelphia Eagles To Win NFC East (+155)

The race for the top spot in the NFC East is much tighter than initially anticipated. The Dallas Cowboys opened up as -120 favorites to defend their title. Now, with the preseason complete, they're neck and neck with the Eagles across most books to win the NFC East.

This is due in large part to the strength of a Philadelphia defense that is ranked fourth on the line and 12th in the secondary by Sharp Football Analysis. They are well suited to test the likes of Ezekiel Elliott, Saquon Barkley, and Antonio Gibson.

Philadelphia also added former Tennessee Titans wide receiver A.J. Brown. Now, quarterback Jalen Hurts has two deep threats with DeVonta Smith returning after 916 receiving yards and five touchdowns in his rookie campaign.

The Eagles have the consensus second-easiest schedule this season, which makes their path to the division crown that much more manageable.

Check out the latest comprehensive and most trusted Sportsbook Reviews by SBR.

Green Bay Packers To Win NFC North (-154)

Green Bay has won eight of the last 11 NFC North titles dating back to the 2011 season. This includes a current stretch of three straight years. They have had little resistance in that span, ending both the 2020 and 2021 seasons with a five-game cushion over second place.

It might have been tough to place this bet considering the loss of Davante Adams, but the struggles of the other three teams in the division make it easier. In the last two seasons, only Green Bay has made it above the .500 mark.

None of the teams around the Packers have done much to improve this offseason. With reigning league MVP Aaron Rodgers in charge of this offense, claiming a fourth straight NFC North crown will not be difficult.

Tampa Bay Buccaneers To Win NFC South (-250)

For a moment, the three other teams in the NFC South had a chance. And then, it immediately vanished when Tom Brady announced he would not, in fact, retire. Brady is restocked with his favorite weapons in Mike Evans and Chris Godwin. He also welcomes former Atlanta Falcons wideouts Julio Jones and Russell Gage to the mix.

Tampa’s defense ranks inside the top 10 on both the line and in the secondary, according to Sharp Football Analysis. They will have no problem causing trouble for Marcus Mariota, Jameis Winson, and whoever starts at quarterback for the Carolina Panthers.

Todd Bowles taking over as head coach will not slow this train down, either. His quarterback has 18 total divisional titles to his credit and wants to prove he has one more Super Bowl run left in him.

Los Angeles Rams To Win NFC West(+130)

The defending Super Bowl champions won a highly competitive NFC West division last season. Los Angeles edged out the Arizona Cardinals by a game and held off San Francisco by two games. The Rams were 3-3 against divisional opponents in 2021.

Their road to a repeat crown will be difficult, having to play the league’s second-toughest schedule, according to Sharp Football Analysis rankings. In that schedule the Rams play the Buffalo Bills, Buccaneers, Kansas City Chiefs, and Packers.

In the end, this will come down to the many changes that have happened to their divisional opponents and the uncertainty they bring. San Francisco is set to start Trey Lance at quarterback, Arizona will be without DeAndre Hopkins for six games, and Seattle sent Russell Wilson to Denver. Expect Los Angeles to rise up among all that chaos.

Where to Bet on NFC Division Winners

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NFC division winner picks made 8/29/2022 at 8:37 p.m. ET

Written By:
Rodrigo Villagomez

Rod has been a contributing author at Sportsbook Review for the last two years specializing in NASCAR and NFL prop betting. He has been writing and podcasting professionally for almost 20 years, spending the last four years in the sports gambling space. Rod has made several appearances on the SiriusXM Fantasy Sports channel. He’s appeared multiple times on the Fantasy Alarm Show with Howard Bender as well as several times over the last two years during the FSGA Draft Week. He is a published author in the academic world with an article on steroids in baseball featured in the Bedford Reader textbook. Rod loves to find non-traditional bets which has led him to dive into the world of defensive and kicking props in football among others. His love of motorsports has translated into several winning weeks of both NASCAR and Formula 1 bets. Rod is a fan first and aims to provide betting picks that are not only profitable but will provide the maximum entertainment value during the sweat. Ultimately, he tries to remember that watching sports should still be fun and anything else is icing on the cake.