First Touchdown Scorer Predictions for Monday Night Football: 49ers vs. Colts TD Picks
My 49ers vs. Colts first touchdown scorer predictions for Monday Night Football are eyeing a juicy payday from either of the two starting tight ends, George Kittle or Ty Warren, or the long shot Brock Purdy as part of our NFL Week 16 predictions.
The 49ers have clinched a playoff spot but are still pushing for a better seed, while the injury-riddled Colts are looking to keep their postseason hopes alive. It all gets underway tonight at 8:15 p.m. ET from Lucas Oil Stadium in Indianapolis (ESPN), with the Niners as the -4.5 betting odds favorite.
🏈 First touchdown scorer predictions: 49ers vs. Colts
See the latest NFL odds and our experts' NFL picks for every game this season.
| Player | Best odds | Confidence |
|---|---|---|
| George Kittle, TE, 49ers | +700 via FanDuel | ⭐⭐⭐⭐ |
| Ty Warren, TE, Colts | +1500 via DraftKings | ⭐⭐⭐⭐ |
| Brock Purdy, QB, 49ers | +2700 via FanDuel | ⭐⭐⭐ |
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George Kittle, TE, 49ers (+700) ⭐⭐⭐⭐
George Kittle is producing one of his finest seasons, especially scoring-wise after reaching pay dirt six times across just nine games. He's been a target behemoth lately while logging nine-plus looks in two of his past three outings, a stretch that includes his season-high 88 yards last week.
And now a rising football magnet gets to face a Colts defense that's given up the eighth-most yards to tight ends, and the unit is tied for the 10th-most receptions.
Our Phil Wood is also eyeing Kittle as part of his 49ers vs. Colts player props.
🙌 More 49ers vs. Colts first TD picks
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Ty Warren, TE, Colts (+1500) ⭐⭐⭐⭐
The Colts will no doubt stay run-focused with the 44-year-old Philip Rivers under center. That will lead to a hefty workload for Jonathan Taylor, but he could end up doing the heavy lifting before Indianapolis needs to turn elsewhere in the red zone.
The Niners have given up just eight rushing touchdowns to running backs all season. Meanwhile, San Francisco has allowed the fifth-most touchdowns to tight ends (nine), which very much brings Ty Warren into play to finish the job.
Brock Purdy, QB, 49ers (+2700) ⭐⭐⭐
Brock Purdy isn't running as much this campaign, surely due to clear self-preservation efforts after being banged up often and missing time.
But while he may not be thought of as being among the speedsters at his position, he possesses the field instincts to diagnose and capitalize on opportunities. We saw that just one season ago, when Purdy posted a quality 323 rushing yards, putting him a respectable 11th at his position. He turned that into five rushing touchdowns, too.
The existence of that skill in his back pocket means it's time to turn to a quarterback once again as our long shot. Dustin Saracini believes too and is taking the Over on the signal-caller's rushing yards in his Brock Purdy player props.
Elsewhere, Mike Spector is locking in on Purdy's primary running back to score a first-half touchdown in his 49ers vs. Colts prediction.
📊 First touchdown scorer odds: 49ers vs. Colts
📺 How to watch Monday Night Football: 49ers vs. Colts
- Date: Monday, Dec. 22
- Kickoff: 8:15 p.m. ET
- Location: Lucas Oil Stadium (Indianapolis)
- TV: ESPN
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