Eagles vs. Chargers Prediction & Odds for Monday Night Football
Last Updated: December 8, 2025 8:15 AM EST • 3 minute read X Social Google News Link
I'm backing the Over in my Eagles vs. Chargers prediction for Monday Night Football (8:15 p.m. ET, ESPN), which takes place at SoFi Stadium in Inglewood, Calif.
The Eagles are the 2.5-point road betting favorite despite defensive tackle Jalen Carter not featuring. As part of the NFL predictions for Week 14, I'm also featuring a Kimani Vidal prop bet.
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After undergoing a procedure on both shoulders, Carter won't feature, significantly altering the complexion of Monday Night Football. Because of that recent development, I'm pivoting to the total, backing the Over.
All three of the Eagles' previous away games in indoor domes went Over this total, including their most recent 24-21 loss at AT&T Stadium to the Dallas Cowboys.
The Chargers, meanwhile, cleared the total in five of their six games at SoFi Stadium, with the 25-10 over the Pittsburgh Steelers in Week 10 the only exception.
The Eagles will find getting pressure on the quarterback markedly more challenging without Carter, who has the second-most QB hits (11) behind Jalyx Hunt (15). Speaking of the Chargers QB, Herbert is listed as questionable after having surgery on his non-throwing hand. I expect him to play, and news of Carter's absence will make life easier for whomever lines up under center.
The Chargers have allowed only 12 points per game over the previous five. However, none of those five teams had a threatening offense, with Jacksonville's 21st-ranked offensive DVOA the most formidable.
If the Over hits, you'll earn $9.01 on a winning $10 bet at bet365. Its -111 odds are the best offered at the best sports betting sites.
Score prediction: Eagles 24, Chargers 20
💡 More Week 14 predictions
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game in Week 14.
Key matchup to watch on MNF
Kimani Vidal vs. Eagles' defense
Omarion Hampton, whom I featured in my Eagles vs. Chargers player props, will return to the Chargers lineup for the first time since Week 5.
While the rookie was and will remain Jim Harbaugh's primary running back, I can't see Los Angeles forgetting about the influence Vidal has had on proceedings in Hampton's absence. Vidal accounted for at least 95 rushing yards in two of the previous three games while averaging 76.2 yards in that sample size.
He'll share the load with Hampton, both of whom will have their eyes on productive outings against an Eagles unit that allowed 281 yards to Chicago last week and concedes the ninth-most yards per carry (tied with three other teams).
FanDuel offers the best price (-114) for his Over. Those odds imply a 53.27% implied probability, and a winning $10 bet will profit $8.77.
Best prop bet: Kimani Vidal Over 35.5 rushing yards (-114 via FanDuel)
Eagles vs. Chargers odds
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Eagles vs. Chargers betting trends
| Eagles | Statistic | Chargers |
|---|---|---|
| 8-4 | W-L record | 8-4 |
| 7-5 | ATS record | 5-6-1 |
| 5-7 | O/U record | 6-6 |
| 5.3 | Yards per play | 5.4 |
| 5.3 | Yards allowed per play | 5.0 |
| +0.4 | Turnover margin | -0.1 |
| 3-2 | Last 5 games | 4-1 |
| L, 24-15 vs. Bears | Previous result | W, 31-14 vs. Raiders |
Eagles vs. Chargers injury report
Eagles vs. Chargers weather
SoFi Stadium is an indoor dome, so the weather won't be a factor.
Check our NFL weather report for the latest forecasts and betting impacts for every game this week.
How to watch Monday Night Football: Eagles vs. Chargers
- Date: Monday, Dec. 8
- Kickoff: 8:15 p.m. ET
- Location: SoFi Stadium (Inglewood, Calif.)
- TV: ESPN
NFL expert picks for Week 14
Follow all of our NFL analysis for Week 14 throughout the week.
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