Eagles vs. Bills Player Props for NFL Week 17 | Best Prop Bets & TD Picks
Last Updated: December 28, 2025 4:30 AM EST • 3 minute read X Social Google News Link
My Eagles vs. Bills player props analyze this potential Super Bowl preview that kicks off from Highmark Stadium in Orchard Park. N.Y., on Sunday at 4:25 p.m. ET (FOX).
Buffalo is a 1.5-point betting favorite, with the game total listed anywhere from 43.5 to 44.5 points.
The last time these two teams faced off in Week 12 of 2023, Jalen Hurts and Josh Allen made history as the only opposing players to each record multiple rushing touchdowns and multiple passing touchdowns. But my NFL Week 17 predictions don't envision that history repeating itself.
🏈 Eagles vs. Bills player prop bets
See the latest NFL odds and our experts' NFL picks for every game this season.
| Player | Prop bet | Best odds | Confidence |
| Saquon Barkley, RB, Eagles | Longest rush Over 15.5 yards | -125 via BetMGM | ⭐⭐⭐⭐⭐ |
| Jalen Hurts, QB, Eagles | Over 30.5 rushing yards | -110 via BetMGM | ⭐⭐⭐⭐ |
| Josh Allen, QB, Bills | Anytime touchdown scorer | +120 via FanDuel | ⭐⭐⭐ |
💰 Eagles vs. Bills best bet
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Saquon Barkley longest rush Over 15.5 yards (-125) ⭐⭐⭐⭐⭐
Philadelphia has been making a concerted effort to get running back Saquon Barkley going before the playoffs, as he's logged 20-plus touches in three straight games.
Barkley has turned those opportunities into quality production, averaging 5.3 yards per rush since Week 14 (seventh-most in the NFL). He's tallied a touchdown in three straight games, and two of his three games with 100-plus rushing yards have come since Week 14.
The tailback faces a Bills defense that's allowed the third-most yards per rush to running backs, and the fourth-most rushing yards per game overall.
🔥 More Eagles vs. Bills prop picks
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game in Week 17.
Jalen Hurts Over 30.5 rushing yards (-110) ⭐⭐⭐⭐
Buffalo has allowed 70-plus rushing yards in two games to quarterbacks this season, while Baker Mayfield and Spencer Rattler each also posted at least 39 yards on the ground.
Jalen Hurts has used his legs more recently, as his rushing totals of 39 and 40 yards over the last two games are the passer's highest since Week 4.
The total here is as high as 32.5 at some of the other best sports betting sites, and the O/U for his rushing attempts sits at 7.5. He's set for a gaudy rushing total this week.
Josh Allen anytime touchdown scorer (+120) ⭐⭐⭐
Josh Allen’s player props, and specifically his rushing yards and rushing attempts, are lower than normal due to concern over the foot injury he suffered last week. But Buffalo still holds a chance to win the AFC East, and Philadelphia’s style of defense should result in Allen scrambling more, even if that’s not a part of the game plan.
Philadelphia allows a league-low in completion rate and passing touchdown rate. Meanwhile, the Bills average the second-most points per drive in home games, and they own the second-highest percentage of touchdowns coming via rushing scores.
📺 How to watch Eagles vs. Bills
- Date: Sunday, Dec. 28
- Kickoff: 4:25 p.m. ET
- Location: Highmark Stadium (Orchard Park, N.Y.)
- TV: FOX
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Mike Spector X social