NFL Divisional Round Schedule & Odds: Betting Lines, Spreads and Totals for Every Game
We look at the NFL odds and Divisional Round lines & spreads, focusing on the biggest line movements and playoff implications for second round of the playoffs.
NFL Divisional Round odds, 2026
The NFL odds for the Divisional Round are via bet365.
| Game | Spread | Moneyline | Over/Under |
|---|---|---|---|
| Bills vs. Broncos (Saturday) | Broncos +1 | BUF -115 / DEN -105 | 46.5 |
| 49ers vs. Seahawks (Saturday) | Seahawks -7.5 | SFO +300 / SEA -380 | 45.5 |
| Texans or Steelers vs. Patriots (Sunday) | Patriots -3 | HOU +130 / NE -155 | 41 |
| Rams vs. Bears (Sunday) | Bears +3.5 | LAR -200 / CHI +165 | 51 |
Our NFL picks will be locked and loaded for Divisional Rounds, with in depth break downs full of predictions. player props, touchdown picks, and parlays.
- We have two games on Saturday:
- The No. 6 Buffalo Bills are a 1-point road betting favorite against the No. 1 Denver Broncos; Buffalo beat No. 3 Jacksonville Jaguars, 27-24, in the opening round
- The No. 1 Seattle Seahawks are a 7.5-point betting favorite against the visiting No. 6 San Francisco 49ers; San Fran beat No. 3 Philadelphia Eagles, 23-19, in the opening round
- We get two games on Sunday:
- The No. 2 New England Patriots will host the No. 5 Houston Texans
- New England beat No. 7 Los Angeles Chargers 16-3
- Houston toppled the Pittsburgh Steelers 30-6 in the Wild Card Round
- The No. 5 Los Angeles Rams are a 3.5-point betting favorite against the No. 2 Chicago Bears
- The Rams beat the No. 4 Carolina Panthers, 34-31, in the opening round
- The Bears knocked off the division rival No. 7 Green Bay Packers, 31-27, in their opening game
Bills vs. Broncos odds: AFC Playoffs
- Kickoff: 4:30 p.m. ET from Empower Field at Mile High (Denver)
- How to watch: CBS
- Early Bills vs. Broncos prediction
49ers vs. Seahawks: NFC Playoffs
- Kickoff: 8 p.m. ET from Lumen Field (Seattle)
- How to watch: FOX
- Early 49ers vs. Seahawks prediction
Texans vs. Patriots odds: AFC Playoffs
- Kickoff: 3 p.m. ET from Gillette Stadium (Foxborough, Mass.)
- How to watch: ESPN/ABC
- Early Texans vs. Patriots prediction
Rams vs. Bears: NFC Playoffs
- Kickoff: 6:30 p.m. ET from Soldier Field (Chicago)
- How to watch: NBC/Peacock
- Early Rams vs. Bears prediction
NFL Divisional Round odds and lines
There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your picks, the harder it becomes to identify edges and secure the best price on most sides or totals.
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