Buccaneers vs. Rams Prediction & Opening Odds for Sunday Night Football: NFL Week 12

My best Buccaneers vs. Rams prediction based on the opening odds for Sunday Night Football focuses on the Rams’ outstanding defense. The Rams are a 6.5-point betting favorite ahead of kickoff from SoFi Stadium in Inglewood, Calif., at 8:20 p.m. ET (NBC).

I expect Los Angeles to cover to be one of the most popular early picks of the week, but my NFL Week 12 predictions recommend making a play on the total instead.

🏈 Early Buccaneers vs. Rams prediction & betting preview

Stay ahead with the rest of our early NFL picks for Week 12.

⬇️  Under 49.5 (-110) ⭐⭐⭐⭐

The Buccaneers have allowed 72 points in their last two games, and they’re allowing an average of 25.0 per game this season. With the Rams averaging 27.9 points per game, this may seem like an easy Over, but the Rams have the second-ranked scoring defense, and they just held the Seattle Seahawks, who were previously averaging over 30 points per game, to 19. 

Four of the Rams’ last five opponents have scored 19 or fewer. Meanwhile, the Buccaneers’ once high-powered offense has scored just nine touchdowns in their last four games. The unit managed just one touchdown against the Detroit Lions and one against the New Orleans Saints, two teams that rank significantly worse than the Rams in scoring.

BetMGM’s price of -110 implies a 52.38% chance this Under hits. A $10 bet would profit $9.09.

📊 Live Buccaneers vs. Rams odds: Week 12

See the latest NFL odds for every game in Week 12.

🔢 Buccaneers vs. Rams opening odds

• Moneyline: Buccaneers +240 | Rams -295
• Spread: Buccaneers +6.5 (-110) | Rams -6.5 (-110)
• Over/Under: Over 49.5 (-110) | Under 49.5 (-110)

↔️ Buccaneers vs. Rams line movement

The Buccaneers just gave up 44 points to the Buffalo Bills, and the week before, they and the New England Patriots combined for 51 points. With Matthew Stafford and the Rams scoring at least 34 in three of four games, I expect this total to increase to 50.5 or 51 before kickoff.

As for the spread, I anticipate the Rams being favored by more than 7 before mid-week. The Buccaneers have lost three of their last four and failed to cover the spread in each of those losses, while the Rams are at home and have been blowing opponents out.

📈 Buccaneers vs. Rams trends & betting notes: SNF

• The Rams have won four of their last five games by at least 14
• The Rams are 7-3 against the spread this season
• The Under has hit in four of the Rams’ last five games
• The Over is 6-2 in the Buccaneers’ last eight games

📺 How to watch Buccaneers vs. Rams: Sunday Night Football

• Date: Sunday, Nov. 23
• Kickoff: 8:20 p.m. ET
• Location: SoFi Stadium (Inglewood, Calif.)
• TV: NBC