NFL Best Bets for Week 15: ATS Predictions & Player Props

My NFL best bets for Week 15 have you covered for an exciting weekend of action, including a divisional rivalry that could act as a playoff eliminator for the losing team, and an NFC matchup of two division winners from a year ago.

The Ravens-Bengals and Lions-Rams tilts are the focus of my traditional ATS and O/U NFL Week 15 predictions. I also expect big games from two running backs who have been a focal point of their team’s offenses of late.

NFL best bets for Week 15

See all of our experts' NFL picks for Week 15 based on the latest NFL odds.

Best NFL predictions: ATS, ML, O/U

Ravens vs. Bengals Over 51.5 (-110) ⭐⭐⭐⭐

These two teams met on Thanksgiving, with Cincinnati winning 32-14. That game saw 46 points scored despite the Bengals settling for three field goals in the red zone, and Lamar Jackson turning in his worst career game from an EPA perspective.

I am expecting a big bounce-back from Baltimore’s offense in this game, coming off an encouraging rushing attack that produced 217 yards against the Steelers. The Ravens only managed 22 points in the home loss, but could have been much more if not for scoring just two touchdowns on six red zone drives (three field goals and a turnover on downs on the others).

With the high end of the market a full point higher at 52.5, I am taking advantage of BetMGM’s standard -110 juice at 52.38% implied odds at a much better number. If the Under cashes, my $10 winning wager would net $9.09 in profits.

Cardinals team total Under 16.5 (-120) ⭐⭐⭐⭐

In the last three weeks, the Texans' defense has not only held Indianapolis 7.5 points under its projected team total but also limited superstar QBs Josh Allen and Patrick Mahomes to a combined 0-to-5 touchdown-to-interception ratio, 56.7% completion percentage, and 44.0 passer rating.

Houston’s defense now leads the NFL in scoring, Total QBR, yards per game, and first downs. As long as it does not have a letdown after three huge games against AFC contenders, it should be able to hold its fourth opponent in five games to fewer than 17 points. 

Compared to the -150 juice at 60% implied odds at the high end of the market, the -120 odds at DraftKings are a steal. If Arizona finishes with 16 or fewer points, my $10 winning wager would return $8.33 in profit.

Lions +6 (-108) ⭐⭐⭐

Sharp action is seemingly behind the NFC-leading Rams in this matchup, as the spread has ticked up from -4.5 to -6 despite Los Angeles receiving just 47% of the spread wagers thus far. But I am still backing Detroit with three stars of confidence as one of my best NFL predictions, as its style of play should give the Rams fits.

Los Angeles’ three losses have come against the Eagles, 49ers, and Panthers, all teams that deploy bruising rushing attacks that could keep Matthew Stafford and his league-high 35 passing touchdowns off the field.

Detroit has also been great in this spot with the head coach-quarterback duo of Dan Campbell and Jared Goff, going 17-3 ATS as an underdog of at least 4 points. It has covered those games by an average of 5.2 points. That is a big reason why I took a flier on the Lions as my best long shot NFL Upset Pick of the week.

Caesars is the only one of our best sports betting sites offering a line as high as +6 at less than the standard -110 juice. Its -108 odds would return $9.26 in profits on a winning $10 wager if the Lions cover.

Best NFL player props for Week 15

Search the best NFL player prop odds for any team or player across every market from legal sportsbooks in your area.

D’Andre Swift player prop: Anytime touchdown scorer (+142) ⭐⭐⭐

Wind chill is going to make it feel like it is below zero degrees in Chicago on Sunday, which suggests there should be a healthy dose of rushing attempts from both teams.

D’Andre Swift has had 10 goal-line rushing attempts since Week 7, the second-most among running backs. And his versatility as a pass catcher is appealing, considering the Browns have allowed the fifth-most targets and receiving yards to running backs this season.

Compared to the +135 anytime touchdown odds at the low end of the market, a $10 winning wager through Caesars’ generous +142 odds would net $0.70 more in profit ($14.20 versus $13.50).

RJ Harvey player prop: Over 74.5 rushing and receiving yards (-115) ⭐⭐⭐⭐

Broncos running back RJ Harvey has averaged 17.7 touches per game since Week 11, a major uptick from his 7.5 average in Weeks 1-10. Harvey played a season-high 69% of the snaps in Week 14, and paid that off in a season-high six targets. 

Since the injury to J.K. Dobbins, Harvey has a 60% snap share, seen two-thirds of the team’s carries, and has received the bulk of the passing game work.

I am backing Harvey’s rushing and receiving yards as opposed to just his rushing yards since he has 19 receptions since Week 9 (eighth-most among running backs), while Green Bay has allowed the eighth-most receptions to the position. 

If Harvey finishes with a combination of 75-plus rushing and receiving yards, my $10 winning wager through bet365’s -115 odds would net $8.70 in profit.