Bears vs. 49ers Predictions for Sunday Night Football | SNF Picks & Odds for Week 17
Last Updated: December 28, 2025 8:20 AM EST • 3 minute read X Social Google News Link
This week’s edition of Sunday Night Football is a big one, so let’s dive into our Bears vs. 49ers predictions as our NFL Week 17 predictions continue. The action is scheduled for Sunday, Dec. 28 at 8:20 p.m. ET (NBC/Peacock) at Levi’s Stadium.
The 49ers are 3-point betting favorites for this one. Both teams are jockeying for a possible shot at the No. 1 seed in the NFC – and a bye – that the Seahawks currently hold.
🏈 Bears vs. 49ers predictions: Sunday Night Football
See the latest NFL odds and our experts' NFL picks for every game this season.
| Predictions | Best odds | Confidence |
|---|---|---|
| 49ers -3 | -112 via DraftKings | ⭐⭐⭐⭐ |
| Kyle Juszczyk Anytime TD Scorer | +500 via DraftKings | ⭐⭐⭐ |
💰 Bears vs. 49ers best bet for SNF
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49ers -3 (-112) ⭐⭐⭐⭐
Ben Johnson and the Chicago Bears have been lucky. With a tremendous turnover margin of +21 – and quarterback Caleb Williams throwing just six interceptions on 19 interceptable passes – that luck will run out. Without turnovers, Chicago’s defense ranks 28th in EPA per play.
San Francisco has looked good with Brock Purdy back. From Week 12 to now, the 49ers’ offense ranks second in EPA per play. The Bears’ offense ranks 13th in that metric over this sample. Injuries are a red flag, but give me San Francisco -3 for -112 (52.8%) at DraftKings.
Score prediction: 49ers 27, Bears 17
🙌 Best Bears vs. 49ers touchdown scorer pick for SNF
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Kyle Juszczyk, FB, SF: anytime TD scorer (+500) ⭐⭐⭐
George Kittle is likely out, leaving the 49ers without their third-leading red-zone target. They’ll have to get creative, which is good for Juszczyk, who has three red-zone targets and one red-zone carry this year. Backup tight end Jake Tonges is good, but Juszczyk should see some opportunities, too.
Juszczyk scored his lone touchdown in a game that Kittle missed earlier this season. At friendly odds of +500 (16.7%) at DraftKings, I love the value here, especially against a defense that is so reliant on forcing turnovers to stop opposing offenses.
📊 Live Bears vs. 49ers odds: SNF
📈 Bears vs. 49ers betting trends: SNF
| Bears | Statistic | 49ers |
|---|---|---|
| 11-4 | W-L record | 11-4 |
| 10-4 | ATS record | 10-5 |
| 7 / 8 | O/U record | 9 / 5 |
| 5.78 | Yards per play | 5.59 |
| 6.11 | Yards allowed per play | 5.67 |
| +21 | Turnover margin | -4 |
| 4-1 | Last 5 games | 5-0 |
| W, 22-16 vs. Packers | Previous result | W, 48-27 vs. Colts |
🌤️ Bears vs. 49ers weather: SNF
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The Bears vs. 49ers weather report doesn’t call for any trouble – it’s 55-degree temperatures, winds less than 10 mph, and a minimal chance of precipitation are in the forecast.
📺 How to watch Sunday Night Football: Bears vs. 49ers
- Date: Sunday, Dec. 28
- Kickoff: 8:20 p.m. ET
- Location: Levi’s Stadium (Santa Clara, Calif.)
- TV: NBC/Peacock
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Isaiah Sirois X social