Bears vs. 49ers Expert Picks for Sunday Night Football | SNF Predictions, Best Bets & Odds

Two of the best teams in the NFC meet tonight with the No. 1 seed at stake as the Chicago Bears (11-4) travel to face the San Francisco 49ers (11-4) on Sunday Night Football (8:20 p.m. ET, NBC). Our Bears vs. 49ers expert picks break down all of our SNF predictions and best bets with the 49ers favored by 3.5 points at Levi's Stadium in Santa Clara, Calif., as part of our NFL Week 17 predictions.

🏈 Bears vs. 49ers expert picks: SNF predictions & best bets

See the latest NFL odds and our experts' NFL picks for every game this season.

🔮 Bears vs. 49ers prediction

49ers -3 (-112) ⭐⭐⭐⭐

Isaiah Sirois: "Ben Johnson and the Chicago Bears have been lucky. With a tremendous turnover margin of +21 – and quarterback Caleb Williams throwing just six interceptions on 19 interceptable passes – that luck will run out. Without turnovers, Chicago’s defense ranks 28th in EPA per play. San Francisco has looked good with Brock Purdy back. From Week 12 to now, the 49ers’ offense ranks second in EPA per play. The Bears’ offense ranks 13th in that metric over this sample."

See Sirois' full analysis in his Bears vs. 49ers predictions, including his favorite player prop bet and the best SNF betting trends, injury report, and more.

🔥 Best Bears vs. 49ers player prop pick

Caleb Williams Over 221.5 passing yards (-115) ⭐⭐⭐⭐⭐

Phil Wood: "Williams has thrown for at least 220 yards in six of his last nine games, with his only three sub-220 performances during that span coming against top-10 pass defenses. The 49ers rank 24th in passing yards allowed, giving up 229.3 per game. And though they’ve held three of the last four quarterbacks they’ve faced to fewer than 200 yards, none of their recent opponents (Philip Rivers, Cam Ward, Shedeur Sanders, and Bryce Young) are nearly as dangerous as Williams."

See Wood's full analysis in his Bears vs. 49ers player props, including his best bet for Christian McCaffrey and Jauan Jennings tonight on Sunday Night Football. We also break down how to bet the 49ers' passing offense in our George Kittle injury update.

🙌 Best Bears vs. 49ers anytime touchdown scorer pick

Luther Burden III, WR, Bears (+225) ⭐⭐⭐⭐⭐

Esten McLaren: "Rookie receiver Luther Burden III (ankle) will return tonight from a one-game injury absence. I'm counting on him to step right back into a role that had him targeted a season-high seven times (six catches for 84 yards) in his last game. He's seen 29 total targets across his last five games, making 20 catches."

See McLaren's full analysis in his anytime touchdown scorer predictions for Sunday Night Football, including a long shot to score at +850 odds. You can follow all of our NFL touchdown props for the biggest games every week.

1️⃣ Best Bears vs. 49ers first touchdown scorer pick

Christian McCaffrey, RB, 49ers (+400) ⭐⭐⭐⭐

Phil Wood: "Christian McCaffrey has scored 16 of the 49ers’ 42 offensive touchdowns, while no other player has more than eight. He’s scored first in three games, and he has a touchdown in 11 of his 15 contests. While the Bears have only allowed 12 rushing touchdowns, they’ve given up 28 passing, which is the fifth-most in the league. Seven of McCaffrey’s touchdowns are through the air."

See Wood's full analysis in his first touchdown scorer predictions for Sunday Night Football, including a 15/1 long shot to score the first touchdown tonight. We break down the projected forecast for the first quarter in our Bears vs. 49ers weather report.

🚀 Bears vs. 49ers same-game parlay

Here's a look at what our NFL expert Brenden Schaeffer is betting tonight with his best Sunday Night Football SGP paying out at +750 odds:

See Schaeffer's full analysis in his Bears vs. 49ers same-game parlay, including his analysis for all three SGP bets for Sunday Night Football. You can follow all of our NFL same-game parlay bets for the biggest games every week.

📊 Bears vs. 49ers odds: SNF

Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game this season.

📺 How to watch Sunday Night Football: Bears vs. 49ers

• Date: Sunday, Dec. 28
• Kickoff: 8:20 p.m. ET
• Location: Levi's Stadium (Santa Clara, Calif.)
• TV: NBC