NFL AI Predictions Week 17 | ATS Picks & Score Projections for Every Game

With two weeks left in the NFL regular season, our NFL AI predictions predict the final score for every Week 17 game - including all three games on Christmas Day - while projecting stat leaders with game previews for the five best bets by our AI model.

We trained the latest ChatGPT model to make its weekly NFL predictions and projected scores for every game this week based on real-time search and advanced metrics. If you can beat the bot in our free weekly NFL contest, you'll enter a draw to win SBR swag while competing for more than $5,000 in total prizes.

🤖 NFL AI predictions for Week 17

See all of our experts' NFL picks for Week 17 based on the latest NFL odds; pick confidence based on a 1-to-5-star scale.

🐆 Jaguars (-6.5) at Colts

Jaguars projected stats

• Passing leader: Trevor Lawrence — 25/37, 285 yards, 3 TD, 1 INT
• Rushing leader: Travis Etienne Jr. — 17 carries, 78 yards, 1 TD
• Receiving leader: Parker Washington — 7 catches, 98 yards, 1 TD

Colts projected stats

• Passing leader: Philip Rivers — 24/36, 268 yards, 2 TD, 2 INT
• Rushing leader: Jonathan Taylor — 16 carries, 72 yards, 1 TD
• Receiving leader: Michael Pittman Jr. — 7 catches, 86 yards

Jaguars vs. Colts prediction

Jacksonville gets the edge because Trevor Lawrence is in the best stretch of his season and this offense is producing touchdowns in waves — including last week in Denver — with Parker Washington emerging as a real volume/efficiency driver alongside their established pieces. The Colts’ current situation at QB creates volatility, and Jacksonville’s ability to win without blitzing lets them play cleaner coverage and hunt takeaways.

Indianapolis can still score — Philip Rivers has shown he can move the ball even in this late-season cameo — but the path is narrower: they need Jonathan Taylor to keep them on schedule and avoid the kind of back-breaking mistakes that turn into short fields. If the Colts fall behind early, Jacksonville’s pace and red-zone production make it hard to trade possessions for four quarters.

Score prediction: Jaguars 30, Colts 20

🟢 Seahawks (-7.5) at Panthers

Seahawks projected stats

• Passing leader: Sam Darnold — 23/35, 262 yards, 2 TD, 1 INT
• Rushing leader: Kenneth Walker III — 18 carries, 82 yards, 1 TD
• Receiving leader: Jaxon Smith-Njigba — 8 receptions, 103 yards, 1 TD

Panthers projected stats

• Passing leader: Bryce Young — 20/34, 214 yards, 1 TD, 1 INT
• Rushing leader: Rico Dowdle — 19 carries, 84 yards
• Receiving leader: Tetairoa McMillan — 6 receptions, 81 yards, 1 TD

Seahawks vs. Panthers prediction

Seattle’s advantage is that it can win this game without being perfect offensively. With Sam Darnold running an efficient, high-floor attack and Kenneth Walker keeping them on schedule, the Seahawks can stack drives and force Carolina to chase points. The matchup also sets up for Seattle to create negative plays on early downs — especially if Carolina’s line is even slightly compromised — which is how favorites cover numbers like this in the high-7 range.

Carolina’s path is real — Rico Dowdle has been productive, and Tetairoa McMillan gives them a legitimate way to generate chunk plays — but the margin gets thin once they fall behind. If Seattle avoids short fields and keeps the game at a controlled pace, the Panthers end up needing long drives to trade scores, which is where one turnover or one stalled red-zone trip flips the game from “competitive” to “comfortable Seahawks win.”

Score prediction: Seahawks 27, Panthers 14

🪖 Patriots (-13.5) at Jets

Patriots projected stats

• Passing leader: Drake Maye — 24/35, 278 yards, 2 TD, 0 INT
• Rushing leader: TreVeyon Henderson — 16 carries, 78 yards, 1 TD
• Receiving leader: Stefon Diggs — 8 receptions, 102 yards, 1 TD

Jets projected stats

• Passing leader: Brady Cook — 20/36, 208 yards, 1 TD, 2 INT
• Rushing leader: Breece Hall — 16 carries, 71 yards
• Receiving leader: Xavier Gipson — 5 receptions, 58 yards

Patriots vs. Jets prediction

New England enters this Week 17 matchup with everything to play for — a division title and playoff seeding — while the Jets are mathematically eliminated and turning over their QB job to rookie Brady Cook. Cook’s early-season sample shows a low completion rate, negative turnover rate, and poor pocket performance, which compounds a Jets passing attack that already ranks near the bottom of the league in passing EPA and efficiency.

The Patriots’ offense has found a rhythm behind Drake Maye, who has posted strong efficiency and downfield production as New England has climbed the standings. Despite multiple players in concussion protocol, Maye still has elite weapons in Stefon Diggs and a defense that can force negative pass plays and turnovers. With the Jets unable to sustain effective drives and New England able to prise open this matchup through rhythm passing and situational rushing, the Patriots control play tempo and extend their lead in the second half.

Score prediction: Patriots 27, Jets 13

🦅 Eagles (+1.5) at Bills

Eagles projected stats

• Passing leader: Jalen Hurts — 24/36, 279 yards, 2 TD, 1 INT
• Rushing leader: Saquon Barkley — 16 carries, 92 yards, 1 TD
• Receiving leader: A.J. Brown — 7 receptions, 104 yards, 1 TD

Bills projected stats

• Passing leader: Josh Allen — 22/35, 243 yards, 2 TD, 1 INT
• Rushing leader: James Cook — 17 carries, 84 yards
• Receiving leader: Khalil Shakir — 6 receptions, 78 yards

Eagles vs. Bills prediction

This matchup is a classic late-season tilt between two playoff teams with contrasting styles, and the injury news is a big part of that story. Buffalo’s Josh Allen is playing through a foot issue and hasn’t practiced — meaning his mobility and ability to extend drives could be limited. The Bills also have several defensive questionables, which creates openings for Philadelphia’s timing-based offense.

Philadelphia’s resurgence under Jalen Hurts has been built on balance. With Saquon Barkley rolling and Lane Johnson back on the line, the Eagles can control tempo and neutralize Buffalo’s pass rush. Meanwhile, the Bills’ offensive inconsistency when Allen can’t run freely and the Eagles’ healthy defensive front plus return of Jalen Carter should tilt key downs in Philly’s favor.

Score prediction: Eagles 27, Bills 23

🐏 Rams (-7.5) at Falcons

Rams projected stats

• Passing leader: Matthew Stafford — 26/36, 312 yards, 3 TD, 1 INT
• Rushing leader: Kyren Williams — 18 rushes, 86 yards, 1 TD
• Receiving leader: Puka Nacua — 9 receptions, 118 yards, 1 TD

Falcons projected stats

• Passing leader: Kirk Cousins — 22/34, 246 yards, 2 TD, 1 INT
• Rushing leader: Bijan Robinson — 17 rushes, 78 yards, 1 TD
• Receiving leader: Drake London — 7 receptions, 92 yards, 1 TD

Rams vs. Falcons prediction

This projection starts with the Rams’ passing game dictating terms. If Davante Adams sits again (he’s been trending the wrong way since re-aggravating the hamstring), the volume consolidates even more around Puka Nacua and the Rams’ tight ends — and Los Angeles can still win through spacing, tempo, and efficiency.

Atlanta can answer in stretches because the offense is built around Bijan Robinson’s workload and Drake London as the go-to target, but the margin gets thin when they’re forced into longer third downs and have to trade touchdowns instead of field goals. If the Rams’ OL shuffles again, it can create a few stalled drives — but over four quarters, Los Angeles’ drive-to-drive scoring pace wins out.

Score prediction: Rams 31, Falcons 20