NFL AI Predictions Week 12: ATS Picks & Score Projections for Every Game

Our NFL AI predictions predict the final score for all 14 games in Week 12 while projecting stat leaders with game previews for the five best bets by our AI model.

We trained the latest ChatGPT model to make its weekly NFL predictions and projected scores for every game this week based on real-time search and advanced metrics. If you can beat the bot in our free weekly NFL contest, you'll enter a draw to win SBR swag while competing for more than $5,000 in total prizes.

🤖 NFL AI predictions for Week 12

See all of our experts' NFL picks for Week 12 based on the latest NFL odds; pick confidence based on a 1-to-5-star scale.

🐯 Bengals (+8.5) at Patriots

🔢 Bengals projected stats

• Passing leader: Joe Flacco – 23/34, 282 yards, 2 TD, 0 INT
• Rushing leader: Chase Brown – 16 rushes, 78 yards, 1 TD
• Receiving leader: Tee Higgins – 8 receptions, 112 yards, 1 TD

🔢 Patriots projected stats

• Passing leader: Drake Maye – 21/33, 219 yards, 1 TD, 1 INT
• Rushing leader: TreVeyon Henderson – 12 rushes, 49 yards
• Receiving leader: Stefon Diggs – 6 receptions, 72 yards

🔮 Patriots vs. Bengals prediction

Cincinnati enters this matchup with a clear stylistic edge: Joe Flacco thrives against teams that make him march the field but don’t generate consistent pressure. New England’s pass rush has been inconsistent all season, and its secondary is still developing, which gives Flacco the leverage to work Tee Higgins on isolation routes.

Expect the Bengals to lean into quick-game concepts early to slow down the Patriots’ front, then pivot into deeper middle-of-the-field shots as the game opens up. For New England, Drake Maye continues to flash the arm talent that made him the franchise cornerstone, but the supporting structure limits sustained scoring. Maye should hit a couple chunk plays, but the projection favors Cincinnati’s ability to finish drives — especially in the red zone.

Score prediction: Bengals 30, Patriots 16

🐦‍⬛ Ravens (-13.5) vs. Jets

🔢 Ravens projected stats

• Passing leader: Lamar Jackson – 19/28, 224 yards, 1 TD, 1 INT; 8 rushes, 48 yards
• Rushing leader: Derrick Henry – 14 rushes, 63 yards, 1 TD
• Receiving leader: Zay Flowers – 7 receptions, 82 yards

🔢 Jets projected stats

• Passing leader: Tyrod Taylor – 17/30, 168 yards, 1 TD, 1 INT
• Rushing leader: Breece Hall – 13 rushes, 54 yards
• Receiving leader: Mason Taylor – 5 receptions, 61 yards, 1 TD

🔮 Ravens vs. Jets prediction

Baltimore’s defense sets the tone in this matchup. Zach Orr's unit thrives on simulated pressure, rotating safety shells, and timed blitzes that force opposing quarterbacks into late decisions. For Tyrod Taylor, this becomes a challenging environment to sustain drives — especially behind a Jets offensive line that has shuffled pieces all year. Expect Baltimore to push the Jets into must-pass situations early and allow its edge rushers can hunt.

Offensively, the Ravens don’t need fireworks to control the game. Lamar Jackson works efficiently from the pocket, leaning on his chemistry with Zay Flowers and Mark Andrews on layered routes that stretch New York’s zones. With a steady dose of Derrick Henry and Keaton Mitchell, Baltimore can stay ahead of schedule and own time of possession. The combination of defensive disruption and red-zone stability gives the Ravens a clear advantage, and over four quarters, the model sees them pulling away with authority.

Score prediction: Ravens 27, Jets 10

🦁 Lions (-10.5) vs. Giants

🔢 Lions projected stats

• Passing leader: Jared Goff – 24/35, 289 yards, 2 TD, 1 INT
• Rushing leader: Jahmyr Gibbs – 17 rushes, 88 yards, 1 TD
• Receiving leader: Amon-Ra St. Brown – 8 receptions, 103 yards, 1 TD

🔢 Giants projected stats

• Passing leader: Jaxson Dart – 20/32, 226 yards, 1 TD, 2 INT
• Rushing leader: Tyrone Tracy Jr. – 15 rushes, 57 yards
• Receiving leader: Wan’Dale Robinson – 7 receptions, 79 yards, 1 TD

🔮 Giants vs. Lions prediction

Outside of last week's mess in Philly, Detroit’s offense is riding high — Jared Goff has settled in and when the line gives him clean pockets, it opens up play-action and vertical looks to Amon-Ra St. Brown and supporting receivers. Jahmyr Gibbs’ burst on early downs keeps the Giants’ linebackers off balance, and the Lions’ tempo should wear New York’s defense down across four quarters. Home field, dominant run game, and a passing attack clicking: the model expects Detroit to take control and never give it back.

The Giants, meanwhile, are in rebuild mode and still shaky in fundamentals. Jaxson Dart shows poise for a rookie, but the coverage schemes he faces and the pressure the Lions bring leave him with few clean windows (assuming he returns this week). The Lions’ defense forces the Giants into long drives and third-and-longs, where Detroit thrives. Expect a few spurts from New York, but Detroit’s structural advantages — especially in situational football — carry them to a convincing cover.

Score prediction: Lions 34, Giants 20

⚜️ Saints (-1.5) vs. Falcons

🔢 Saints projected stats

• Passing leader: Tyler Shough – 23/35, 241 yards, 1 TD, 0 INT
• Rushing leader: Alvin Kamara – 15 rushes, 64 yards; 4 receptions, 38 yards
• Receiving leader: Chris Olave – 7 receptions, 89 yards, 1 TD

🔢 Falcons projected stats

• Passing leader: Kirk Cousins – 19/31, 214 yards, 1 TD, 1 INT
• Rushing leader: Bijan Robinson – 18 rushes, 92 yards, 1 TD
• Receiving leader: Drake London – 6 receptions, 72 yards

🔮 Falcons vs. Saints prediction

This matchup profiles as one of the tightest games of Week 12, with New Orleans’ disciplined defense offsetting Atlanta’s playmaking talent on the ground. The Saints’ ability to stay structurally sound in coverage limits explosive opportunities for Drake London, forcing Kirk Cousins to operate underneath and sustain longer drives. New Orleans’ pass rush doesn’t have a single overwhelming star, but its depth and blitz timing disrupt enough plays to create pressure moments, including one projected takeaway that swings possession and expected points.

Offensively, the Saints lean on Alvin Kamara’s multipurpose reliability to dictate tempo. Chris Olave draws favorable leverage throughout the game, particularly on intermediate crossers where Atlanta’s zone spacing has been inconsistent. While the Falcons generate chunk plays in the run game behind Bijan Robinson, their red-zone execution remains streaky — a recurring theme throughout their season. Ultimately, New Orleans’ edge in third-down conversions and turnover margin stabilizes the final minutes, allowing the Saints to grind out a narrow home victory.

Score prediction: Saints 22, Falcons 20

⛏️ 49ers (-7.5) vs. Panthers

🔢 49ers projected stats

• Passing leader: Brock Purdy – 21/30, 248 yards, 2 TD, 0 INT
• Rushing leader: Christian McCaffrey – 17 rushes, 92 yards, 1 TD
• Receiving leader: Jauan Jennings – 5 receptions, 77 yards, 1 TD

🔢 Panthers projected stats

• Passing leader: Bryce Young – 20/34, 188 yards, 0 TD, 1 INT
• Rushing leader: Rico Dowdle – 14 rushes, 56 yards
• Receiving leader: Tetairoa McMillan – 6 receptions, 71 yards

🔮 Panthers vs. 49ers prediction

San Francisco enters Week 12 with a clear structural edge in both phases, and the matchup trends strongly toward its strengths. Brock Purdy’s efficiency in the quick and intermediate passing game forces Carolina into predictable zone looks, and Kyle Shanahan’s motion-heavy approach keeps linebackers in conflict. Expect Christian McCaffrey to be a consistent chain-mover against his former team, with the Panthers struggling to match San Francisco’s physicality at the point of attack.

The Panthers struggle to generate explosive plays, and Bryce Young’s development has been slowed by protection inconsistencies and a limited supporting cast. Star rookie receiver Tetairoa McMillan gives them some juice on the perimeter, but the 49ers’ defensive line disrupts timing before Carolina’s routes can develop. Sustained drives are difficult, red-zone efficiency is a major issue, and the 49ers’ ability to win early downs produces a controlled, methodical victory. The projection sees Carolina settling for field goals while San Francisco’s offense maintains a comfortable multi-score cushion.

Our Gary Pearson's NFL picks against the spread are also riding with the Niners.

Score prediction: 49ers 27, Panthers 9