NFL AI Predictions Week 10: ATS Picks & Score Projections for Every Game

We've reached the halfway point of the season with our NFL AI predictions for Week 10, which predict the final score for all 14 games this week while offering stat leaders and game preview for the five best bets by our AI model.

We trained the latest ChatGPT model to make its weekly NFL predictions and projected scores for every game this week based on real-time search and advanced metrics. If you can beat the bot in our free weekly NFL contest, you'll enter a draw to win SBR swag while competing for more than $5,000 in total prizes.

🤖 NFL AI predictions for Week 10

See all of our experts' NFL picks for Week 10 based on the latest NFL odds.

🐎 Broncos (-9.5) vs. Raiders

🚨 Raiders vs. Broncos projected score

• Broncos 26, Raiders 13

🔢 Broncos projected stats

• Passing leader: Bo Nix – 23/33, 245 yards, 2 TD, 0 INT
• Rushing leader: J.K. Dobbins – 18 rushes, 84 yards, 1 TD
• Receiving leader: Courtland Sutton – 7 receptions, 96 yards, 1 TD

🔢 Raiders projected stats

• Passing leader: Geno Smith – 21/34, 219 yards, 1 TD, 1 INT
• Rushing leader: Ashton Jeanty – 15 rushes, 61 yards
• Receiving leader: Tre Tucker – 6 receptions, 73 yards, 1 TD

🔮 Raiders vs. Broncos prediction

Denver’s front seven has become one of the most disruptive in the league, and that pressure should be the difference against Las Vegas. Bo Nix continues to protect the ball and work efficiently off play-action, leaning on J.K. Dobbins to keep drives balanced and manageable. Courtland Sutton’s chemistry with Nix gives Denver an intermediate safety valve that routinely moves the chains.

The Raiders will hit some perimeter plays with Geno Smith’s timing and his receivers' route precision, but they’ve struggled to sustain drives behind a shaky interior line. Denver’s bend-but-don’t-break defense and red-zone efficiency tilt this matchup toward a comfortable home win.

🦬 Bills (-9.5) vs. Dolphins

🚨 Bills vs. Dolphins projected score

• Bills 30, Dolphins 17

🔢 Bills projected stats

• Passing leader: Josh Allen – 24/36, 292 yards, 3 TD, 1 INT
• Rushing leader: James Cook – 17 rushes, 78 yards
• Receiving leader: Keon Coleman – 6 receptions, 94 yards, 1 TD

🔢 Dolphins projected stats

• Passing leader: Tua Tagovailoa – 26/36, 276 yards, 1 TD, 1 INT
• Rushing leader: De'Von Achane – 13 rushes, 67 yards, 1 TD
• Receiving leader: Jaylen Waddle – 8 receptions, 103 yards

🔮 Bills vs. Dolphins prediction

Buffalo’s defense has rediscovered its identity with disciplined rush lanes and tighter zone spacing, and that structure matches up well with Miami’s timing-based attack. Josh Allen doesn’t need to play hero ball — just let James Cook’s versatility keep the Dolphins honest and strike when Keon Coleman and Dalton Kincaid win in isolation. Expect a few highlight scrambles from Allen, but the real edge lies in Buffalo’s ability to finish drives once inside the 30.

Without Tyreek Hill, Miami’s explosive ceiling narrows and Jaylen Waddle becomes the focal point for Tua Tagovailoa and the passing attack. The Dolphins still move it between the 20s, but finishing drives is the gap: Buffalo converts more short-field chances, Miami settles for too many checkdowns, and the Bills win by two scores.

🟢 Seahawks (-6.5) vs. Cardinals

🚨 Cardinals vs. Seahawks projected score

• Seahawks 27, Cardinals 13

🔢 Seahawks projected stats

• Passing leader: Sam Darnold – 23/34, 268 yards, 2 TD, 1 INT
• Rushing leader: Kenneth Walker III – 17 rushes, 86 yards, 1 TD
• Receiving leader: Cooper Kupp – 7 receptions, 98 yards, 1 TD

🔢 Cardinals projected stats

• Passing leader: Jacoby Brissett – 21/33, 214 yards, 0 TD, 1 INT
• Rushing leader: Zonovan “Bam” Knight – 12 rushes, 55 yards, TD
• Receiving leader: Marvin Harrison Jr. – 6 receptions, 87 yards

🔮 Cardinals vs. Seahawks prediction

Seattle’s plan is straightforward: win first down with Kenneth Walker and Zach Charbonnet, then let Sam Darnold work intermediate rhythm throws to Cooper Kupp and Jaxon Smith-Njigba. If the Seahawks stay on schedule, Arizona’s pass rush can’t pin ears back, and Seattle’s red-zone designs give it a finishing edge.

Arizona fights through injuries to Kyler Murray (IR) and Trey Benson (IR) with Jacoby Brissett’s efficiency and Marvin Harrison’s ability to win one-on-ones, but the run game is committee-driven and light on explosives. A couple of stalled red-zone trips plus one turnover swing this toward a comfortable Seattle cover.

🦁 Lions (-8.5) vs. Commanders

🚨 Lions vs. Commanders projected score

• Lions 31, Commanders 17

🔢 Lions projected stats

• Passing leader: Jared Goff – 25/35, 301 yards, 2 TD, 0 INT
• Rushing leader: Jahmyr Gibbs – 16 rushes, 92 yards, 1 TD
• Receiving leader: Amon-Ra St. Brown – 8 receptions, 103 yards, 1 TD

🔢 Commanders projected stats

• Passing leader: Marcus Mariota – 20/31, 214 yards, 1 TD, 1 INT; 7 rushes, 46 yards
• Rushing leader: Jacory Croskey-Merritt – 13 rushes, 64 yards
• Receiving leader: Deebo Samuel – 7 receptions, 88 yards, 1 TD

🔮 Lions vs. Commanders prediction

Detroit’s offensive balance is the difference here. Jared Goff has time to operate behind an elite line, and Jahmyr Gibbs’ burst through light boxes gives the Lions steady chunk gains on early downs. Amon-Ra St. Brown keeps moving the chains with precision routes underneath, and the Lions' motion packages should keep Washington’s linebackers in conflict all afternoon.

For Washington, Jayden Daniels is out for the year, putting backup Marcus Mariota in a tough spot against a Lions front anchored by Aidan Hutchinson and Alim McNeill. Without a consistent deep threat beyond Terry McLaurin, who is trending toward remaining out for this game, the Commanders will struggle to match Detroit’s scoring pace. If the Lions stay efficient in the red zone, they’ll extend drives and finish this one comfortably.

🦅 Eagles (+2.5) at Packers

🚨 Eagles vs. Packers projected score

• Eagles 23, Packers 20

🔢 Eagles projected stats

• Passing leader: Jalen Hurts – 22/32, 246 yards, 2 TD, 1 INT; 8 rushes, 42 yards
• Rushing leader: Saquon Barkley – 15 rushes, 72 yards
• Receiving leader: A.J. Brown – 7 receptions, 97 yards, 1 TD

🔢 Packers projected stats

• Passing leader: Jordan Love – 21/34, 238 yards, 1 TD, 1 INT
• Rushing leader: Josh Jacobs – 17 rushes, 86 yards, 1 TD
• Receiving leader: Christian Watson – 5 receptions, 78 yards

🔮 Eagles vs. Packers prediction

Philadelphia’s plan travels: win early downs with light boxes against Saquon Barkley, then let Jalen Hurts stress Green Bay’s underneath zones with RPOs and quick hitters to A.J. Brown and DeVonta Smith. If the Eagles keep negative plays off schedule, their red-zone sequencing (QB runs + isolation throws) is the tiebreaker in a cold-weather grinder.

Green Bay answers with Josh Jacobs behind a physical interior and Jordan Love working play-action shots to Christian Watson, but sustained explosives are tough against an Eagles secondary that tightened up before the deadline. One late stop plus a Hurts scramble conversion nudges Philly over the line at Lambeau.