NFL 2+ Touchdown Scorer Predictions: Best TD Picks to Score Twice in Week 16

We have our eyes on Saquon Barkley and Kareem Hunt to help us cash a massive TD parlay this week.
Philadelphia Eagles running back Saquon Barkley (26) reacts after scoring a touchdown as part of our NFL 2+ touchdown scorer predictions.
Pictured: Philadelphia Eagles running back Saquon Barkley (26) reacts after scoring a touchdown as part of our NFL 2+ touchdown scorer predictions. Photo by Bill Streicher-Imagn Images
Enjoying SBR content? Add us as a preferred source on your Google account Add as a preferred source on Google

My NFL 2+ touchdown parlay today focuses on two running backs to find pay dirt with the 2-leg parlay returning $900 on a $10 wager.

My NFL Week 16 predictions explain why Philadelphia Eagles running back Saquon Barkley and Kansas City Chiefs running back Kareem Hunt are my best TD picks to score two touchdowns this week.


🏈 NFL 2+ touchdown scorer predictions for Week 16

See all of our experts' NFL picks for Week 15 based on the latest NFL odds.

Player Odds (FanDuel) Profit ($10 bet) Confidence
Saquon Barkley, RB, Eagles +550 $55 ⭐⭐⭐⭐⭐
Kareem Hunt, RB, Chiefs +1300 $130 ⭐⭐⭐⭐
Combined +9000 $900 ---

🔥 Best NFL 2+ touchdown scorer bets today

Search the best NFL player prop odds for any team or player across every market from legal sportsbooks in your area.

Saquon Barkley, RB, Eagles (+550) ⭐⭐⭐⭐⭐️

Barkley hasn't had the year he expected to have in 2025, but has an opportunity to finish the year strong while gearing up for the playoffs. The good news for Barkley, is that he is going up against a defense in the Washington Commanders' that will have a near impossible task of shutting down this Eagles' offense. 

Barkley has been a weapon in both the rushing and passing attack this year, combining for eight touchdowns on the season. The Commanders' defense ranks fifth to last in rushing yards allowed per game, and they have gotten worse as the season has progressed. I expect the Eagles' game plan to feature Barkley as much as possible in a must-win game for playoff positioning, and if they can execute, he should have no issues cashing this leg of the 2+ touchdown scorer parlay.

Kareem Hunt, RB, Chiefs (+1300) ⭐⭐⭐⭐

Hunt enters Week 16 with a completely new offense surrounding him. The Chiefs will be without star quarterback Patrick Mahomes for the rest of the season, and Rashee Rice is also going to be missing this game with a concussion. The good news for Hunt and Chiefs fans, is that they are playing the two-win Tennessee Titans. The Chiefs will need to heavily feature the rushing attack to not allow Gardner Minshew to force turnovers, which he is susceptible of doing. 

The Titans have allowed the second most rushing touchdowns in the league this year at 19. The Chiefs have nothing to play for in this game, but neither do the Titans, who are barely competitive at this point in the season. I expect the Chiefs offense to still be able to put up points, and Hunt will be the red zone beneficiary. 


🚀 Best NFL 2+ touchdown scorer parlay

Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game in Week 15.

Img 5423

Subscribe to our brand-new SBR newsletter!
Subscribe to our brand-new SBR newsletter!

📃 Affiliate disclosure

Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)