Lakers vs. Clippers Player Props & Best Bets Today: NBA Prop Picks for Jan. 22

The stars will be out in full force in Los Angeles as we drop our best Lakers vs. Clippers player props.
Los Angeles Lakers guard Luka Doncic - who's featured in my Lakers vs. Clippers player props - reacts after a play in the third quarter.
Pictured: Los Angeles Lakers guard Luka Doncic - who's featured in my Lakers vs. Clippers player props - reacts after a play in the third quarter. Photo by: Isaiah J. Downing-Imagn Images
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We've got the battle of Los Angeles on our hands, and I'm dropping my best Lakers vs. Clippers player props to get you ready for the 10:00 p.m. ET tipoff from the Intuit Dome in Inglewood, Calif. (Prime Video).

The Clippers come into tonight as narrow 1.5-point betting favorites, but they'll be in tough trying to stop the dynamic duo of Luka Doncic and LeBron James. Let's dig in.


🏀 Lakers vs. Clippers player props today: 10:00 p.m. ET

See all of our experts' NBA picks based on the latest NBA odds.

Player Prop bet Best odds Confidence
Luka Doncic, Lakers Over 31.5 points -125 via FanDuel ⭐⭐⭐⭐⭐
LeBron James,  Lakers Over 7.5 assists  +146 via FanDuel ⭐⭐⭐⭐
James Harden, Clippers Over 27.5 points -104 via FanDuel ⭐⭐⭐⭐

💰 Best Lakers vs. Clippers prop bet: Luka to pour in Over 31.5 points (-125) ⭐⭐⭐⭐⭐

Check out all of our NBA analysis and expert predictions this season.

Opponents are shooting 47% from the field against the Clippers, whose lazy team defense did them in against the Chicago Bulls on Tuesday in a 138-110 loss. If you get lackadaisical against Doncic, he's going to eat you alive. Look for Doncic to steal the show and to go over this number for the seventh time this month. Fire him up with confidence as part of our best Lakers vs. Clippers player props.


🔥 More Lakers vs. Clippers prop picks

James to facilitate tonight, go Over 7.5 assists (+146) ⭐⭐⭐⭐

The old man may not have the same scoring touch as he used to, but damn, he still has his vision. LeBron has gone Over this number in three of his last five games, and has recorded double-digit assists three times this month. We're likely looking at 32-34 minutes of playing time from the King tonight, which should be enough to cash this plus-money play.

Feeling a little more conservative on this line? Our Shane Thurston has you covered in his NBA player props & best bets, with a play on the 6.5 assist line.

Harden puts on a show, goes Over 27.5 points (-104) ⭐⭐⭐⭐

The math here is simple - the Lakers allow opponents to shoot 48.7% from the field, which is one of the worst marks in the NBA, and Harden is one of the best ball-handlers and spot-up shooters in basketball (when he wants to be). Look for Harden to get loose and help the Clippers go on a handful of runs tonight in what should be a close game wire-to-wire.


How I'm handicapping Lakers vs. Clippers

I looked at tonight like this: we have two high-powered offenses in the Lakers and Clippers (second and third in true shooting percentage, respectively), battling against subpar defenses on either side (24th and 23rd in defensive rating, respectively). If I were betting on the total, I'd also take the Over at 222.5. Yes, they are both slow-paced teams, but the efficient offense on both sides will outweigh the pace in the end. Remember to bet within your means and protect your bankroll.


🚀 Lakers vs. Clippers SGP

💵 Lakers vs. Clippers same-game parlay

  • Luka Doncic Over 31.5 points (-125) ⭐⭐⭐⭐⭐
  • LeBron James Over 7.5 assists (+146) ⭐⭐⭐⭐
  • James Harden Over 27.5 points (-104) ⭐⭐⭐⭐

Best odds: +769 via FanDuel ($10 to win $79.86)


📈 Lakers vs. Clippers betting trends

Lakers Statistic Clippers
26-16 W-L record 19-24
23-19 ATS record 20-23
25-17 O/U record 21-22
5-5 Last 10 games 7-3

🚑 Lakers vs. Clippers injuries


📺 How to watch Lakers vs. Clippers

  • Date: Thursday, Jan. 22, 2026
  • Tipoff: 10:00 p.m. ET
  • Location: Intuit Dome (Inglewood, Calif.)
  • TV: Prime Video

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