Manny Pacquiao vs. Mario Barrios: Betting Odds and Lines for Saturday's Fight in Las Vegas

The Pacquiao vs. Barrios odds have settled in the days leading up to the shocking return of the Filipino boxing legend. It's been nearly four years since Manny Pacquiao (62-8-2, 39 KOs) retired, losing his last fight.

But despite his age (46), a tilt with WBC welterweight champion Mario Barrios (29–2–1, 18 KOs) at the MGM Grand lured him back. The best boxing betting sites aren't convinced, as evidenced by the rare eight-division world champion getting +210 betting odds. Unsurprisingly, Barrios, on the other hand, is the betting favorite with -280 odds.

The ring walk for the main event is set for 11 p.m. ET.

📊 Pacquiao vs. Barrios odds

Here are the Manny Pacquiao vs. Mario Barrios odds via FanDuel as of July 18:

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🆚 Pacquiao vs. Barrios odds: Method of victory

In addition to betting on the fight result, Caesars is also offering various prop bet markets on Pacquiao vs. Barrios - including the winning method of victory, round-by-round betting, and whether the fight will go the distance.

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🔢 Pacquiao vs. Barrios odds: Round-by-round betting

You can also bet on the exact outcome for this fight based on the round it ends at DraftKings. The market states that the fight must end in the selected round for the wager to be a winner.

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⌛ Pacquiao vs. Barrios odds: Will the fight go the distance?

bet365 is offering odds if the 12-round bout between these two will go all the way, and if not, which round either of the fighters might end the bout in.

Those -125 odds for the fight to end before the final bell suggest a 55.56% chance that the bout will not go the distance. However, with only -110 odds on the fight to go all the way, there isn't a heavy lean on either side.

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What round will the fight end?

You can also bet on which round the fight will end in, regardless of which boxer emerges victorious. 

👊 Pacquiao vs. Barrios odds: Knockdowns

While we can expect this prop bet market to open up as we get closer to the fight, BetMGM is already offering odds on "Down But Not Out"

🥊 Pacquiao vs. Barrios tale of the tape

📺 Pacquiao vs. Barrios fight info

• When: Saturday, July 19, 2025
• Where: MGM Grand, Las Vegas, Nevada
• How to watch: Showtime Pay-Per-View (PPV)
• Favorite: Mario Barrios (-280; bet $280 to win $100)
• Underdog: Manny Pacquiao (+210; bet $100 to win $210)

Boxing fans have many more upcoming bouts to look forward to, as we break down the Oleksandr Usyk vs. Daniel Dubois odds for July 19 in London, and the biggest boxing match of the year is covered in the Canelo Alvarez vs. Terence Crawford odds for Sept. 13 in Las Vegas.

🤖 AI prediction & fight analysis

We asked ChatGPT to break down this fight between Manny Pacquiao and Mario Barrios, including profiles for each fighter and a Pacquiao vs. Barrios prediction. While the popular OpenAI chatbot is not a traditional sports betting model, it can often spot trends or insights that bettors may overlook.

🥊 Manny Pacquiao

Record: 62-8-2 (39 KOs) Age: 46 Stance: Southpaw

✅ Strengths:

• Speed & angles: Even at his age, Pacquiao’s hand speed and ability to attack from unconventional angles remain elite
• Experience: An 8-division world champion with decades of experience against top-tier opponents
• Footwork: Still demonstrates solid lateral movement and ring IQ, often out-positioning less experienced fighters

❌ Weaknesses:

• Age & activity: He hasn’t fought since 2021, and at 46, his durability and stamina are real concerns
• Volume decline: No longer throws punches in bunches like he did in his prime; tends to conserve energy

🥊 Mario Barrios

Record: 28-2 (18 KOs) Age: 30 Stance: Orthodox

✅ Strengths:

• Youth & activity: At 30, Barrios is in his athletic prime and has fought actively in recent years
• Size & reach: Taller with a 4-inch reach advantage, he can keep Pacquiao at bay with his jab
• Durability: Took Gervonta Davis into the later rounds and bounced back strong in recent fights

❌ Weaknesses:

• Defense: Can be hit clean, especially against fast, aggressive opponents
• Lack of big-name wins: While talented, Barrios hasn’t defeated a fighter of Pacquiao’s caliber or pedigree

🔮 Pacquiao vs. Barrios fight prediction

While Pacquiao’s legacy and skillset are unquestionable, Barrios’ youth, size, and recent activity give him the edge in a 12-round fight. Expect Pacquiao to start fast and create early excitement, but Barrios’ pressure and output will likely wear the legend down in the later rounds.

✅ Prediction: Mario Barrios by Unanimous Decision (UD)
📈 Value pick: Pacquiao by split decision if he controls early rounds and surprises with volume

❓ Manny Pacquiao vs. Mario Barrios FAQ

Who is the favorite between Manny Pacquiao vs. Mario Barrios?

Mario Barrios is the current betting favorite over Manny Pacquiao. The welterweight champ owns -280 odds, whereas the Filipino legend is a massive +210 underdog.

How old are Manny Pacquiao and Mario Barrios?

Manny Pacquiao is coming into this fight as a 46-year-old, Mario Barrios is a much younger 30.

When is the Manny Pacquiao vs. Mario Barrios fight?

The Pacquiao vs. Barrios fight will take place at the MGM Grand in Las Vegas on Saturday, July 19.

How to watch Manny Pacquiao vs. Mario Barrios?

You can watch the fight live on Prime Video PPV on July 19. The main card begins at 8 p.m. ET, with the ring walk for the main event at 11 p.m. ET.

💰 How to bet on boxing

1. Moneyline bets (straight up winner)

The most straightforward bet in boxing is a moneyline bet, which is just picking who you think will win the fight. In this type of bet, the odds will indicate which fighter is the favorite and which one is the underdog. The favorite will have negative odds (like -150), meaning you have to bet more to win a smaller amount, while the underdog will have positive odds (like +200), meaning you can win more relative to your bet if they pull off an upset.

• Example: Let’s say Fighter A is listed at -150, and Fighter B is listed at +200. If you bet $150 on Fighter A and they win, you’d make $100. But if you bet $100 on Fighter B and they win, you’d make $200.

2. Over/Under (total rounds)

Another popular bet is the over/under on the number of rounds in the fight. Oddsmakers will set a line, typically between 7 and 10 rounds, and you’ll bet whether the fight will last more or fewer rounds than that. If you think a fight will end quickly, you’d bet the under, and if you think it’ll be a back-and-forth slugfest, you’d bet the over.

• Example: If the Over/Under is set at 8.5 rounds, and you bet the Over, the fight must last 9 rounds or longer for your bet to win. If it’s stopped before 9 rounds, the Under wins.

3. Method of victory

With this bet, you’re wagering on how the fight will end, not just who will win. There are a few typical outcomes you can bet on: a KO/TKO, decision (the fight goes the distance and is decided by the judges), or a draw.

• Example: You could bet on Fighter A to win by knockout at +300, meaning a $100 bet would win $300 if Fighter A knocks out their opponent. Or, if you think the fight will go the distance and be decided by judges' scorecards, you could bet on Fighter A to win by decision at +150.

4. Round betting

For a more precise bet, you can wager on which round the fight will end in. This bet is a little trickier but can offer a higher payout because you're predicting a more specific outcome. If you’re confident in a fighter's ability to end the fight early or think they’ll tire out and win later, this can be a fun way to bet.

• Example: You could bet that Fighter A wins in round 3 at odds of +800. If the fight ends in round 3, you’ll win your bet and collect the higher payout.

5. Parlay betting

If you’re feeling confident in multiple outcomes, you can combine several boxing bets into a parlay. A parlay lets you bet on multiple fighters, methods of victory, or even fights on the same card. All your selections must win for you to cash in, but the potential payout increases with each additional leg in the parlay.

• Example: You could parlay Fighter A to win with Fighter B to win by knockout. If both bets hit, you’ll get a bigger payout than if you had placed each bet individually.

6. Prop bets

Boxing also offers a variety of prop bets, which are unique and sometimes very specific to the fight. These bets can cover anything from how many punches a fighter will throw to whether the fight will end in a particular round or whether there will be a knockdown.

• Example: A prop bet might be “Will Fighter A score a knockdown in round 2?” at odds of +500. If Fighter A does score a knockdown in that round, you’ll win the bet.

7. Live betting

Once the fight begins, many sportsbooks offer live betting. This allows you to place bets on the fight as it progresses, adjusting your wagers based on what’s happening in real time. For example, if a fighter you bet on is getting knocked around early but you still think they have a chance to turn it around, you can place a bet on them at more favorable odds as the fight unfolds.

Tips for betting on boxing:

• Know the fighters: The more you know about the boxers - things like their fighting style, history, and physical condition - the better your chances of making a smart bet. Are they knockout artists? Do they struggle with endurance? These are important factors to consider.
• Look at recent form: A fighter’s recent performance is often a better indicator of future success than their overall record. If a fighter’s been on a hot streak or has recently struggled with injuries, that might affect how they perform.
• Consider the fight’s venue: Some boxers perform better in certain locations or under certain conditions (e.g., altitude, temperature, home crowd). This could give one fighter an edge over the other.

💵 Best boxing betting sites

Want to bet on Manny Pacquiao vs. Mario Barrios? Here are the best sports betting sites and best sportsbook promos for betting on boxing:

• FanDuel Promo Code | Read our FanDuel Review
• DraftKings Promo Code | Read our DraftKings Review
• Hard Rock Bet Promo Code

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