Roughriders vs. Stampeders Prediction, CFL Betting Odds & Expert Picks: Week 12

Can the Roughriders get revenge on the Stampeders for their lone loss this season?
Roughriders vs. Stampeders prediction
Pictured: Saskatchewan Roughriders wide receiver KeeSean Johnson is key to our Roughriders vs. Stampeders prediction. Photo by John E. Sokolowski via Imagn Images.

The Grey Cup odds-leading Saskatchewan Roughriders have a shot to avenge their only loss this season when they take on the Calgary Stampeders tonight at 7 p.m. ET (TSN, CFL+) from McMahon Stadium in Calgary. With this game essentially being a pick'em, my Roughriders vs. Stampeders prediction is backing the road team behind a big performance from KeeSean Johnson.


📊 Roughriders vs. Stampeders odds: Week 12

Live updated odds from our best sports betting sites.

📈 Roughriders vs. Stampeders betting odds analysis

These are the two best teams in the league, with both being led by a CFL Most Outstanding Player odds contender at QB, which is why it's no surprise that this is essentially a pick'em. Given the play of Vernon Adams Jr. and Trevor Harris, and both being backed by top-tier defenses, this game is a toss-up, and the betting odds reflect that ahead of kickoff. I don't think either team should be viewed as more than a 2-point betting favorite.


🏈 Roughriders vs. Stampeders expert picks

CFL picks made Friday; odds subject to change.

✅ Moneyline pick: Roughriders (-110 via Caesars) ⭐⭐⭐⭐
✅ Against the spread pick: Roughriders +1 (-120 via
bet365) ⭐⭐⭐⭐
✅ Over/Under pick: Under 51.5 (-110 via Caesars) ⭐⭐⭐

Sbr Post Product 16 9 Picks

🔮 Roughriders vs. Stampeders prediction & best bet

🔎 Our NEW player props odds tool can help you find the best CFL odds across legal sportsbooks in your area!

🌾 Roughriders ML (-110) ⭐⭐⭐⭐

The Roughriders have one loss this season, and it was at the hands of the Stampeders, but that game had a strange air around it, literally. It was postponed last minute due to poor air quality, after the players had arrived at the stadium - it was played the next day. This time around, the Roughriders shouldn't start flat, especially with the way they've played since that loss.

Since losing to Calgary, they've won four straight and just hammered Grey Cup contenders in two straight games, beating the Hamilton Tiger-Cats, 29-9, and the Montreal Alouettes, 34-6. The Riders have the best against-the-spread record in the CFL (7-2), and all we need them to do to cash this bet is win, which they've done eight times in nine games this season.

For as good as the Stampeders are, no team is better or more well-rounded than Saskatchewan. The Roughriders are second in the league in points per game (29.1) and yards per game (400.2), with their defense allowing the fewest points per game (20.3) and yards per game (337.1). Plus, Adams will be down his best receiver with Dominique Rhymes out (quad).

If Saskatchewan can win this time around, a $10 bet pays a $9.09 profit.

Bet $1, Get Twenty 100% Profit Boosts

New users only. Must use promo code. Min. $10 deposit. Max. bonus is twenty 100% Profit Boost tokens. Profit Boost tokens expire in 14 days. Void where prohibited. Full terms.    

Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.


💰 Best Roughriders vs. Stampeders player prop bet

Roughriders vs. Stampeders prediction
Pictured: Roughriders receiver KeeSean Johnson is the focus of our Roughriders vs. Stampeders prediction. Photo by John E. Sokolowski via Imagn Images.

🔥 KeeSean Johnson anytime TD scorer (+110) ⭐⭐⭐

Scoring could be hard to come by in this game with these being the two best defenses in the CFL, but if the Roughriders are going to win, they need Johnson to continue stepping up. The former Fresno State star is fifth in the CFL in receiving yards (682) and he's found the end zone in two of his last three games.

While A.J. Ouellette (+175) is an enticing anytime TD scorer to bet for the Riders, the star running back hasn't scored in five straight games, and the Stamps have allowed a league-low two rushing touchdowns this season. If Johnson can score, a $10 bet pays an $11 profit.

Bet $5, Get $300 in Bonus Bets + Over $200 Off NFL Sunday Ticket

21+ and present in most states. (18+ DC/KY/NH/WY). Void in OR/NH. 1 per customer. $5+ first-time bet req. Get promo code to redeem NFL Sunday Ticket sub and max. $300 issued as non-withdrawable bonus bets; 7 day expiry.

Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.


🚑 Roughriders vs. Stampeders injuries


📺 Roughriders vs. Stampeders game info

  • When: Saturday, Aug. 23
  • Kickoff: 7 p.m. ET
  • Where: McMahon Stadium (Calgary, Alberta)
  • How to watch: TSN, CFL+

❓Roughriders vs. Argonauts FAQs

Who is the favorite to win Roughriders vs. Argonauts?

The Roughriders are a slight favorite, with -110 moneyline odds, but they can still be had at +1 with this being a toss-up between the two best teams in the CFL.

How do CFL spread odds work?

When betting on the CFL, the favorite needs to win by a certain number of points to cover the "point spread" - also known as the betting line. Conversely, the underdog needs to lose by fewer than the points displayed in the spread or win outright to cash. For example, a 3-point favorite would need to win by a field goal or more to reward bettors.

How do CFL moneyline odds work?

When betting on the CFL, the underdog will have the "longer" odds and is typically priced at "plus-money" odds that indicate the profit on a $100 bet. For example, a team with +150 odds would turn a $100 bet into a $150 profit - or a $10 bet into a $15 profit - according to our odds converter.

Where can I find the best CFL betting odds?

Shop around our best sportsbooks to find the best odds for your CFL picks. Our best sports betting apps for all sports include BetMGM, bet365, Caesars, FanDuel, and DraftKings - one of which is featured in our best sportsbooks in Canada.

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.