Blue Bombers vs. Tiger-Cats Prediction, Odds & Expert Picks: CFL Week 15 Best Bets

Last Updated: September 12, 2025 9:00 AM EDT • 5 minute read X Social Google News Link

The Hamilton Tiger-Cats look to build on their success at home when they host the Winnipeg Blue Bombers tonight at 7 p.m. ET (TSN/RDS, CBSSN) from Hamilton Stadium. With Winnipeg being down QB Zach Collaros, my Blue Bombers vs. Tiger-Cats prediction is taking Hamilton to cover as a 6.5-point betting favorite, as part of our CFL picks.
🏈 Blue Bombers vs. Tiger-Cats prediction
CFL expert picks for Friday; odds subject to change.
- Moneyline pick: Tiger-Cats (-330 via BetMGM) ⭐⭐
- Against the spread pick: Tiger-Cats -6.5 (-115 via BetMGM) ⭐⭐⭐⭐
- Over/Under pick: Over 52 (-110 via Caesars) ⭐⭐⭐
📝 Blue Bombers vs. Tiger-Cats preview & best bet
🐯 Tiger-Cats -6.5 (-115) ⭐⭐⭐⭐

The Tiger-Cats bounced back from their Labour Day Classic heartbreak in a big way, beating the Montreal Alouettes 26-9 on the road last week. Hamilton QB Bo Levi Mitchell and this explosive offense should be able to stack another big win tonight at home against a Blue Bombers team that's dealing with several key injuries, chief among them being their star QB in Collaros.
Without Collaros, Winnipeg is going to have a difficult time keeping up with a Hamilton offense that ranks second in the league in points per game (29.9) and the only real Grey Cup odds threat in the East Division. Mike O'Shea's defense has been uncharacteristically inconsistent this season, too, allowing 26.7 points per game and giving up 27-plus in seven of its last nine.
If Mitchell and his wide receivers are on the same page, Hamilton should cruise to a win. The Tiger-Cats are 6-4 ATS since Week 4, and if they can cover again, which they have a 53.49% implied probability of doing by these odds, a $10 bet pays an $8.70 profit.
💰 Best Blue Bombers vs. Tiger-Cats player prop bet
⬆️ Bo Levi Mitchell Over 304.5 passing yards (-125) ⭐⭐⭐⭐

Mitchell has been ageless this season and sits atop the CFL Most Outstanding Player odds thanks to the video game numbers he's been putting up. The two-time CFL MOP leads the league in TD passes (24) and sits second in passing yards (3,653), having topped 304.5 in five of his last seven games.
These odds at DraftKings imply a 55.56% probability Mitchell will hit the Over, with a $10 winning bet paying an $8 profit.
📊 Blue Bombers vs. Tiger-Cats odds: Week 15
CFL odds update live in real time.
📈 Blue Bombers vs. Tiger-Cats betting odds analysis
The Tiger-Cats opened as a 4.5-point home favorite against the Blue Bombers, with the line seeing serious movement due to Collaros' injury. Since Winnipeg ruled out their starting QB, our best sports betting sites have shifted the line further in Hamilton's direction, with most books offering the Tiger-Cats between -6.5 and -7.5. I don't expect much more movement before kickoff.
🔢 Blue Bombers vs. Tiger-Cats stats
Season stats courtesy of CFL.ca.
Blue Bombers (6-6) | Statistic (per game) | Tiger-Cats (7-5) |
---|---|---|
26.3 | Points | 29.9 |
26.7 | Points allowed | 27.2 |
244.0 | Passing yards | 295.8 |
110.9 | Rushing yards | 85.8 |
267.8 | Passing yards allowed | 268.4 |
91.4 | Rushing yards allowed | 103.2 |
🚑 Blue Bombers vs. Tiger-Cats injury report
Courtesy of the CFL Week 15 injury report.
Blue Bombers | Tiger-Cats |
---|---|
Zach Collaros, QB (head - out) | None |
Deatrick Nichols, DB (hip - questionable) | |
Jamal Parker, DB (leg - out) | |
Kyrie Wilson, DB (ankle - questionable) | |
Jerreth Sterns, WR (shoulder - out) |
📺 Blue Bombers vs. Tiger-Cats game info
- When: Friday, Sept. 12
- Kickoff: 7 p.m. ET
- Where: Hamilton Stadium (Hamilton, Ontario)
- How to watch: TSN/RDS, CBSSN
❓ Blue Bombers vs. Tiger-Cats FAQs
Who is favored to win Blue Bombers vs. Tiger-Cats?
The Tiger-Cats are a -300 moneyline favorite at home against the Blue Bombers.
What is the spread for Blue Bombers vs. Tiger-Cats?
The Tiger-Cats are 6.5-point betting favorites at home against the Blue Bombers.
What is the Over/Under for Blue Bombers vs. Tiger-Cats?
The Over/Under for Blue Bombers vs. Tiger-Cats is set at 52.5.
What are the best bets for Blue Bombers vs. Tiger-Cats?
The best bets for Blue Bombers vs. Tiger-Cats are Hamilton -6.5 and Bo Levi Mitchell Over 304.5 passing yards.
When is the Blue Bombers vs. Tiger-Cats game?
The Blue Bombers vs. Tiger-Cats game is Friday, Sept. 12 at 7 p.m. ET (TSN/RDS, CBSSN) from Hamilton Stadium.
How do CFL odds work?
When betting on the CFL, the point spread shows how many points the favorite needs to win by in order to cash the bet. For example, a favorite of -3 must win by more than 3 points to cover the spread, while an underdog at +3 must win outright or lose by fewer than 3 points to cover the spread.
Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total will be higher or lower than the set number.
You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.
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Rob Paul X social