Dodgers vs. Padres Odds, Predictions & Best Bet for Tuesday, June 10

After losing a heart-breaker on Monday, San Diego should get revenge with Dylan Cease on tap.

Last updated: June 10, 2025 6:12 PM EDT • 3 min read

Dodgers vs. Padres Odds, Predictions & Best Bet for Tuesday, June 10 — Pictured: San Diego Padres third baseman Manny Machado celebrates after hitting a double against the Los Angeles Dodgers. Photo by David Frerker via Imagn Images.

The San Diego Padres will be out for revenge tonight after losing in heartbreaking fashion on Monday against the rival Los Angeles Dodgers. Our Dodgers vs. Padres odds and prediction expect a reversal of fortune for the home favorites tonight at 9:40 p.m. ET (SDPA) from Petco Park in San Diego.

⚾ Dodgers vs. Padres odds today

Here are the live odds for today's Dodgers vs. Padres matchup. See all of today's MLB odds for the latest lines from our best MLB betting sites.

🔮 Dodgers vs. Padres prediction & picks

🔎 Our NEW MLB player prop odds tool can help you find the best odds for your MLB picks.

✅ Who will win Dodgers vs. Padres: Padres (-118 via FanDuel) ⭐⭐⭐⭐
✅ Best player prop pick: Manny Machado Over 1.5 total bases (+105 via Caesars) ⭐⭐⭐⭐

💰 Dodgers vs. Padres best bet

Here is my best bet for today's Dodgers vs. Padres matchup:

💪 Padres to win

Best odds: -118 via FanDuel (bet $10 to win $8.47 profit)
Implied win probability: 54.13%

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We were on the wrong end of Monday's extra-innings thiller, but I truly can't believe the Padres aren't dealing as bigger favorites ahead of this rematch tonight.

San Diego trots out ace Dylan Cease (4.72 ERA), who has endured a frustrating start but has been better than the surface stats suggest with a 3.20 FIP and 3.24 SIERA - both top-20 marks among qualified starters. He also boasts MLB's second-best swinging strike rate (15.9%), a positive sign for regression.

I'd much rather back him than likely Dodgers starter Matt Sauer (3.05 ERA). The 26-year-old owns a career 5.11 ERA and has allowed multiple runs in three straight appearances, all in four innings or less. I don't expect him to have much success against the Padres' bats - especially Manny Machado, who is hitting a sizzling .389 in June with at least two total bases in five straight games.

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Written By:
C Jackson Cowart

C Jackson Cowart is a publishing editor and lead writer for Sportsbook Review. An award-winning writer, reporter, and editor with a decade of sports media experience, "C-Jax" has worked with ESPN, Forbes, theScore, and various daily newspapers before joining the Sportsbook Review team. He's a proud graduate of the University of North Carolina, where he served as a beat writer for the Tar Heels' championship run through the NCAA men's basketball tournament in 2017. Jackson has spent the last five years covering sports betting as a predictive analyst, features writer, and industry reporter. Since joining the team in 2023, he's played a key role in Sportsbook Review's coverage of the Super Bowl, March Madness, and NBA playoffs while serving as the lead writer for the growing WNBA and NASCAR betting scenes. Though he's cashed some big bets over the years -- including Lamar Jackson to win MVP (twice) -- he's still haunted by enough second-place bet slips to wallpaper his home office. While Jackson is a committed "process over results" bettor with a keen eye for advanced stats and subtle bias in futures markets, he also embraces sports betting as a vehicle for entertainment and personal investment. He's written about everything from hot dogs to groundhogs and still hasn't forgiven his "inside source" for a sabotaged bet on the Gatorade color in Super Bowl LV.