Cubs vs. Brewers Prediction, Odds & Best Bets: Can Chicago Head Back to Wrigley on a High?

Only two games separate these teams in the NL Central standings, so we have our work cut out for us while trying to pick who will win this showdown on Wednesday afternoon.

Andrew Brennan

Last Updated: July 30, 2025 1:25 PM EDT • 4 minute read

Cubs vs. Brewers Prediction, Odds & Best Bets: Wednesday, July 30 — Pictured: Chicago Cubs pitcher Shota Imanaga is a big reason we're backing the visitors to win with our Cubs vs. Brewers prediction. Photo by Matt Marton via Imagn Images.

Not much is separating these NL Central rivals this season, so our Cubs vs. Brewers prediction will look to take a side on a game that's being priced fairly close to a coin flip by the best sports betting sites.

We have an exciting pitching showdown on tap when this one gets underway at 2:10 p.m. ET from American Family Field. Our Cubs vs. Brewers best bets are backing Shota Imanaga and the Cubs, and we expect Seiya Suzuki's bat to heat up after a prolonged cold spell.

Cubs vs. Brewers prediction: Cubs to win (+105 via bet365) ⭐⭐⭐⭐
Best Cubs vs. Brewers player props: Seiya Suzuki Over 1.5 hits + runs + RBIs (+115 via DraftKings) ⭐⭐⭐⭐⭐

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✅ Cubs vs. Brewers prediction: Cubs to win (+105 via bet365)

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This is a tricky one, as both teams send their aces to the mound for today's game, which is likely why the best sports betting apps have it priced so tightly. I'm going to ride with the plus-money odds on the Cubs in the hopes that they can find the form that led them to winning the first two games of this season series before dropping the last three.

Milwaukee stomped Chicago in each of the last two games, winning by a combined score of 17-7. However, I expect the Cubs to bounce back with Imanaga on the mound and Brewers star outfielder Jackson Chourio sidelined.

As you'll see below, I'm expecting a particular Cubs slugger to break out of a prolonged slump, and, hopefully, the rest of the lineup follows.

💰 Best Cubs vs. Brewers player props

✅ Best Cubs vs. Brewers player prop: Seiya Suzuki Over 1.5 hits + runs + RBIs (+115 via DraftKings)

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I featured Suzuki in my home run predictions today, but this is his player prop I'm most interested in. As one of the bets I made personally this morning, this serves as a five-star play.

I like Suzuki to cash this prop for many of the same reasons I outlined why I picked him to hit a home run. His batted-ball data still looks good even during his slump, and I think he just needs to make a few minor tweaks to get back on track.

Freddy Peralta is a tough pitcher to face, but I believe Suzuki is good enough to cash this Over against any MLB starter. Fire it up with confidence.

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❓MLB betting FAQs

How do betting odds work?

Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common.

What is the run line in baseball?

The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.

What does moneyline mean in betting?

The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet - just pick the winner.

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Written by:
Andrew Brennan

Andrew Brennan is a publishing editor for Sportsbook Review. He also heads the website’s MLB coverage, from the various futures markets to daily picks. Andrew believes a math-based approach is the best way to enjoy long-term success in sports betting, and he’s spent the better part of the last year fine-tuning his own process for MLB, NBA, and NFL picks. Andrew uses eight different sportsbooks to find the best odds available and various projection models to gather as much information as he can. His most used sportsbooks are bet365, FanDuel, and theScore Bet. When it comes to daily projection models, he regularly references NumberFire across all sports, as it’s one of the best free tools available. In terms of which daily markets Andrew attacks, he almost exclusively bets on pitcher strikeouts for baseball. When the winter rolls around, you’ll see him providing more variety when it comes to the NBA (points, assists, rebounds) and NFL (almost any offensive-based player prop). He used these tools to go +150 units in 2023. Andrew is also a passionate fantasy sports player. He’s played fantasy football, fantasy Premier League, and fantasy baseball for the last decade. He graduated from Durham College with his diploma in journalism after earning his degree in law from Carleton University. He’s worked in sports media since early 2017, first contributing at FanSided before moving to theScore. He joined SBR in 2022.