Brewers vs. Mariners Prediction, Odds & Best Bets: Who Takes Rubber Match in Seattle?

Last Updated: July 23, 2025 3:05 PM EDT • 4 minute read X Social Google News Link

Seattle snapped Milwaukee's 11-game winning streak in the second game of the series, but my Brewers vs. Mariners prediction expects the visitors to get back on track this afternoon.
The best sports betting sites list Seattle as a -130 betting favorite with ace Luis Castillo on the bump. First pitch is set for 3:40 p.m. ET (ROOTNW, FDSN Wisconsin) from T-Mobile Park in Seattle, and both the betting public and our Dustin Saracini expect this game to start with zeroes. He's included it in his best NRFI bets today, and it's the most-bet NRFI at BetMGM.
I'm going against the grain with my Brewers vs. Mariners best bets and picking the World Series odds contenders to clinch a road series victory behind William Contreras and other hot bats.
- Brewers vs. Mariners prediction: Brewers to win (+116 via FanDuel) ⭐⭐⭐
- Best Brewers vs. Mariners player props: William Contreras Over 0.5 singles (-105 via DraftKings) ⭐⭐⭐⭐
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✅ Brewers vs. Mariners prediction: Brewers to win (+116 via FanDuel)
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My Brewers vs. Mariners prediction backs the hottest team in baseball to get back on track after dropping a game for the first time in its last 12 outings.
While Castillo has been stellar at home this season (2.06 ERA), his 4-3 record tells the story of Seattle struggling to provide him with run support. Only five teams - the Royals, Marlins, White Sox, Guardians, and Rangers - score fewer than the Mariners' 3.88 runs per game on home soil.
Meanwhile, Milwaukee turns to the oft-reliable Quinn Priester, who has only allowed 11 runs across his last five starts.
The Brew Crew is unbeaten in their last five showdowns with Priester starting, largely due to their stellar offense. Pat Murphy's men have been especially great on the road, averaging 5.31 runs per game.
My Brewers vs. Mariners best bet banks on the visitors bouncing back after being blanked on Tuesday. I'll take baseball's most in-form team to return to the win column at plus-money (+116 with our best sports betting apps) with moderate confidence.
💰 Best Brewers vs. Mariners player props
✅ Best Brewers vs. Mariners player prop: William Contreras Over 0.5 singles (-105 via DraftKings)
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Castillo has pitched some of the players in Milwaukee's lineup extremely well over his career. However, one individual who has found some slight success against Seattle's ace is Contreras. He's clubbed three hits - two of which were singles - in six career at-bats against Castillo.
My best Brewers vs. Mariners player prop feels comfortable betting on Contreras to get a base-knock after his seven-game hitting streak came to an end on Tuesday. He's heavily juiced at our best sportsbooks to get a hit, so we're taking a flier on a more specific market to get a bit more bang for our buck in this series finale.
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How do betting odds work?
Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common.
What is the run line in baseball?
The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.
What does moneyline mean in betting?
The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet - just pick the winner.
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