Best Home Run Predictions Today: MLB Odds, Picks & Prop Bets for Sept. 30

Last Updated: September 30, 2025 6:00 AM EDT • 3 minute read X Social Google News Link

After correctly identifying at least one home run hitter in four straight profitable days to end the regular season, we are back to continue the momentum in the MLB playoffs with our best home run predictions today.
My MLB picks focus on at least one slugger from each of the other three wild-card round games, while doubling up on the Reds-Dodgers tilt.
Michael Busch, Freddie Freeman, Shohei Ohtani, and Giancarlo Stanton make up my home run MLB picks today. If all of them homer, the four-leg $10 parlay would net over $2,800 in profits.
💰 MLB best home run predictions & odds today: Sept. 30
Best home run predictions today based on the latest MLB odds.
- Michael Busch to hit a home run (+390 via FanDuel) ⭐⭐
- Giancarlo Stanton to hit a home run (+350 via BetMGM) ⭐⭐
- Shohei Ohtani to hit a home run (+195 via DraftKings) ⭐⭐⭐
- Freddie Freeman to hit a home run (+407 via DraftKings) ⭐⭐⭐
💣 Best home run prediction today: MLB expert picks & prop bets
Here is my favorite MLB home run bet today and analysis of why it leads my MLB home run predictions.
⚾ Freddie Freeman (Dodgers) to hit a home run ⭐⭐⭐

Freeman was an absolute menace in the postseason last year, putting the team on his back in often the most clutch situations, and doing so while nursing an injured ankle.
Freeman belted four home runs in 20 postseason at-bats last year. He enters this postseason having slashed .277/.373/.519 in 62 career playoff games, and his 1.364 OPS in last year’s run to the World Series was his best individual postseason.
Freeman has four hits in 15 career at-bats with one home run against Reds righty Hunter Greene.
The Dodgers are one of two teams to tag Greene for multiple home runs in his previous six starts, both of which came from Andy Pages.
Freeman’s best home run implied odds are 21.74% through FanDuel’s +360 odds. But the best return on a winning $10 wager is through DraftKings’ +407 odds, which would net $40.70 in profits if Freeman homers.
Our Dustin Saracini previews the series in his MLB wild-card round predictions.
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📊 Reds vs. Dodgers odds
🚀 Best home run parlay picks
Use our parlay calculator to get the best odds for any parlay.
- Michael Busch to hit a home run (+390 via FanDuel)
- Giancarlo Stanton to hit a home run (+330 via FanDuel)
- Shohei Ohtani to hit a home run (+190 via FanDuel)
- Freddie Freeman to hit a home run (+360 via FanDuel)
Parlay odds: +28007 via FanDuel ($10 to win $2,800.74)
Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.
💡 Expert MLB predictions today
- MLB home run predictions today
- MLB player props today
- Tigers vs. Guardians player props
- Padres vs. Cubs player props
- Red Sox vs. Yankees player props
- Reds vs. Dodgers player props
📃 Affiliate disclosure
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Mike Spector X social