Best Home Run Predictions Tonight: MLB Odds, Picks & Prop Bets for Dinger Tuesday

We've put together four tasty home run picks for Dinger Tuesday, featuring some of baseball's biggest stars, including Bryce Harper.

Sean Tomlinson

Last updated: May 20, 2025 11:38 AM EDT • 3 min read

Best home run predictions today — Pictured: Philadelphia Phillies infielder Bryce Harper celebrates. Photo by Kyle Ross via Imagn Images.

Bryce Harper looks to be the latest to give us a lesson in how to bet on the worst team in baseball as part of our best home run predictions tonight, and he'll lead the charge on Dinger Tuesday.

Be sure to continue ahead for our best prediction and home run parlay, which pays out over $7000 in profit if it hits!

💰 MLB best home run predictions & odds tonight: Dinger Tuesday

Here are my best home run predictions and odds tonight, with my pick confidence based on a 1-to-5-star scale. You can also check out our MLB player prop odds tool for the latest MLB odds at the best legal sportsbooks in your region.

🧨 Bryce Harper to hit a home run (+340 via FanDuel) vs. Rockies ⭐⭐⭐⭐
🧨 Zach Neto to hit a home run (+375 via bet365) vs. Athletics ⭐⭐⭐
🧨 Mookie Betts to hit a home run (+450 via bet365) vs. Diamondbacks ⭐⭐⭐
🧨 Bobby Witt Jr. to hit a home run (+575 via bet365) vs. Giants ⭐⭐⭐

🚀 Best home run parlay picks

Here is our best MLB home run parlay for Tuesday's baseball action; use our parlay calculator to get the best odds for any parlay.

💣 Bryce Harper to hit a home run (+300)
💣 Zach Neto to hit a home run (+375)
💣 Mookie Betts to hit a home run (+450)
💣 Bobby Witt Jr. to hit a home run (+575)

Parlay odds: +70437 via bet365 ($10 to win $7,053.75)

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💣 Best home run prediction tonight: MLB expert picks & prop bets

Here's a breakdown of my best home run prop prediction tonight. Check out the rest of our MLB picks along with our guide on how to bet on MLB.

⚾ Bryce Harper (Phillies) to hit a home run ⭐⭐⭐⭐

Best odds: +340 via FanDuel (bet $10 to win $34)

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Coors Field is a magnetizing force in this market, and especially so with the Rockies even more hapless than usual this season while sporting MLB's worst ERA at 5.85.

Toss that in with the baseball-pulverizing Philadelphia Phillies visiting the launchpad of the thin Colorado mountain air, and it's easy to see where our top home run pick for today will come from. But which Phillies slugger offers the most appealing value at our best MLB betting sites?

The woeful ways of the Rockies are baked in all around, but particularly through the +220 given to Kyle Schwarber. Meanwhile, Bryce Harper is sitting at +340, and he gets to come from the left side against spiraling righty Antonio Senzatela.

Harper is producing a quality season thus far, though he hasn't quite lifted off yet in the way we're used to seeing. But the under-the-hood metrics indicate that could change real soon, as he sits in the 87th percentile or above in hard-hit percentage and launch-angle sweet spot, according to Baseball Savant.

Even more encouraging, Harper's expected slugging of .508 is far above his actual slugging percentage of .440. And he gets to pummel Senzatela tonight, who's been dreadful and seems destined to get worse while resting in the bottom 3% in expected batting average and slugging allowed, and ERA.

📊 Phillies vs. Rockies odds

💵 Best MLB betting sites

Want to bet on baseball? Check out the best MLB betting sites and best sportsbook promos for today's games:

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Written By:
Sean Tomlinson

Sean Tomlinson has been in the sports media wilderness since 2009, and he joined Sportsbook Review in 2021. His work has been referenced in The New York Times and Forbes. He's also made appearances on The Fan 590 and TSN 1050. Sean is a regular bettor who places bets daily while using a handful of books. Most frequently, he uses FanDuel and bet365 due to the quality experience on those apps. While he'll often take an analytical approach, Sean enjoys the fun, recreational side of betting too, and embraces alternative markets on events like the Westminster Dog Show or Eurovision, or the many novelty props tied annually to the Super Bowl, for example. Beyond sports, Sean is also interested in the betting markets tied to politics, and especially those connected to American elections. He sees betting as a way to explore and engage in a deeper way, and takes that same view to his work. He plays poker periodically too, and is an avid fantasy sports player. Sean also previously spent time with Bleacher Report and theScore, all after earning his media studies degree from the University of Guelph-Humber.