Wisconsin vs. Michigan Prediction: College Football Week 6 Odds & Expert Picks

Last Updated: October 3, 2025 5:15 PM EDT • 3 minute read X Social Google News Link

My Wisconsin vs. Michigan prediction projects the Badgers will continue struggling against power-conference opponents.
Our college football predictions for Week 6 have the Wolverines winning this Big Ten matchup decisively as a 17-point betting favorite. Kickoff from Michigan Stadium in Ann Arbor, Mich., is set for noon ET (FOX) on Saturday.
My college football picks for this matchup also lean into a player prop involving the Michigan rushing attack, which I expect will expose the Wisconsin run defense as less effective than current statistics suggest.
🏈 Wisconsin vs. Michigan predictions
College football expert picks for Week 6; odds subject to change.
- Game pick: Michigan -17 (-110 via Caesars)⭐⭐⭐⭐
- Over/Under pick: Under 43.5 (-110 via BetMGM) ⭐⭐⭐
- Player prop bet: Justice Haynes Over 103.5 rushing yards (-115 via BetMGM) ⭐⭐⭐⭐
✅ Wisconsin vs. Michigan expert pick
Track the latest college football scores for line movement and matchup info.
〽️ Michigan -17 (-110) ⭐⭐⭐⭐
Wisconsin is 1-3 against the spread, with an average ATS margin of -7.9 points per game. The Badgers have managed just 24 points across two games against power-conference opponents (Alabama and Maryland), losing those contests by 24 and 17 points, respectively.
Though Wisconsin has shut down opposing rushing attacks (50 rushing yards allowed per game, second in the nation), it hasn’t faced an offense that runs it like the Wolverines. Plus, the woeful Badger offense ranks 109th in FBS in adjusted efficiency.
Michigan has conquered its two home opponents by 17 and 60 points, respectively, and boasts a top-20 defense in yards per game that should effectively stop the Wisconsin offense in its tracks.
The best line on the home team's spread at publish time is Michigan -17 (-110) at Caesars. The implied probability of these odds is 52.38%. A winning $10 wager would profit $9.09.
💰 Best Wisconsin vs. Michigan player prop bet
Our college football player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
⬆️Justice Haynes Over 103.5 rushing yards (-115) ⭐⭐⭐⭐
Wisconsin’s run defense, on paper, is impressive. But I’m targeting Michigan’s Justice Haynes for his rushing prop in this matchup, under the premise that the Badgers’ strong ground-defense statistics are largely the result of teams attacking them through the air.
Alabama showed virtually no run game against Wisconsin, but it played that matchup without RB Jam Miller - and Ty Simpson got whatever he wanted through the air.
The Badgers haven’t faced a running back like Haynes, who has topped 103.5 rushing yards in all four games this season. Michigan is likely to rely on Haynes more heavily than previous Wisconsin opponents have used their rushing attacks.
The best odds on Haynes’ rushing prop come from BetMGM, with -115 odds on Over 103.5 yards. The implied probability of these odds is 53.49%. A winning $10 wager on this prop would profit $8.70.
📊 Wisconsin vs. Michigan odds
Latest college football odds updated live in real time.
📺 How to watch Wisconsin vs. Michigan: Week 6
- Date: Saturday, Oct. 4
- Kickoff: Noon ET
- Where: Michigan Stadium (Ann Arbor, Mich.)
- TV: FOX
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Brenden Schaeffer X social