College Football Playoff Predictions: CFP Picks, Odds & Best Bets for Semifinals
Last Updated: January 9, 2026 9:51 PM EST • 2 minute read X Social Google News Link
Just three teams remain in the hunt for the college football national championship, and our College Football Playoff predictions feature our best college bowl game predictions for the CFP semifinals ahead of Oregon vs. Indiana on Friday. Who will face Miami in the national championship game? Our best bets include our top ATS picks, player props, and touchdown scorer bets break down the season's penultimate game.
🏈 Oregon vs. Indiana predictions & odds (Jan. 9 @ 7:30 p.m. ET)
The Big Ten takes center stage in the second College Football Playoff semifinal matchup with Oregon and Indiana facing off for the second time this season. The Hoosiers got the best of the Ducks when they met in Autzen Stadium back on Oct. 11 en route to their first undefeated season in school history - that also marks the only loss all season for Dan Lanning and Co. ahead of their second appearance in the CFP semifinals. This is also a rematch between Fernando Mendoza and Dante Moore, the likely top two picks by the latest NFL draft odds, while these defenses are among the most loaded in the sport.
Live Oregon vs. Indiana odds
Oregon vs. Indiana prediction
🔴 Indiana -3.5
The last time these two programs played, Indiana announced itself as the best team in the country with a 10-point road win against Oregon. This time around, the Hoosiers are the clear top team in the country, ranked No. 3 on offense and No. 2 on defense by SP+.
- via Rob Paul's Oregon vs. Indiana prediction
More Oregon vs. Indiana picks
- Oregon vs. Indiana prediction
- Oregon vs. Indiana player props
- Oregon vs. Indiana anytime touchdown scorer predictions
- Oregon vs. Indiana same-game parlay
- Fernando Mendoza player props
- Dante Moore player props
- Oregon vs. Indiana expert picks
📅 College Football Playoff schedule & odds: CFP semifinals
See the latest college football odds and our college football picks for every bowl game. All games will be televised on ESPN.
| Kickoff (ET) | Matchup (seed) | Favorite |
|---|---|---|
| Thursday, Jan. 8 @ 7:30 PM | Miami (10) vs. Ole Miss (6) | Miami -3.5 |
| Friday, Jan. 9 @ 7:30 PM | Oregon (5) vs. Indiana (1) | Indiana -3.5 |
💰 More college football bowl predictions & expert picks
- College football opt-out tracker
- College football bowl game odds & schedule
- College bowl game predictions
- College football bowl rankings
- Top 100 players in College Football Playoff
- College bowl game mascot rankings
- Free college football playoff bracket
- CFP national championship look-ahead odds
- College Football Playoff semifinal best bets
- CFP semifinal anytime touchdown scorer predictions
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