Drugs found in drinking water

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  • The Seer
    SBR Posting Legend
    • 10-29-07
    • 10641

    #1
    Drugs found in drinking water
    No wonder everyone's f***ed up.

    AP probe: Drugs found in drinking water

    By Jeff Donn, Martha Mendoza and Justin Pritchard, Associated Press writers
    A vast array of pharmaceuticals — including antibiotics, anti-convulsants, mood stabilizers and sex hormones — have been found in the drinking water supplies of at least 41 million Americans, an Associated Press investigation shows.
    To be sure, the concentrations of these pharmaceuticals are tiny, measured in quantities of parts per billion or trillion, far below the levels of a medical dose. Also, utilities insist their water is safe.


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    But the presence of so many prescription drugs — and over-the-counter medicines like acetaminophen and ibuprofen — in so much of our drinking water is heightening worries among scientists of long-term consequences to human health.

    In the course of a five-month inquiry, the AP discovered that drugs have been detected in the drinking water supplies of 24 major metropolitan areas — from Southern California to Northern New Jersey, from Detroit to Louisville

    Water providers rarely disclose results of pharmaceutical screenings, unless pressed, the AP found. For example, the head of a group representing major California suppliers said the public "doesn't know how to interpret the information" and might be unduly alarmed.

    How do the drugs get into the water?

    People take pills. Their bodies absorb some of the medication, but the rest of it passes through and is flushed down the toilet. The wastewater is treated before it is discharged into reservoirs, rivers or lakes. Then, some of the water is cleansed again at drinking water treatment plants and piped to consumers. But most treatments do not remove all drug residue.

    And while researchers do not yet understand the exact risks from decades of persistent exposure to random combinations of low levels of pharmaceuticals, recent studies — which have gone virtually unnoticed by the general public — have found alarming effects on human cells and wildlife.

    "We recognize it is a growing concern and we're taking it very seriously," said Benjamin H. Grumbles, assistant administrator for water at the U.S. Environmental Protection Agency.

    Members of the AP National Investigative Team reviewed hundreds of scientific reports, analyzed federal drinking water databases, visited environmental study sites and treatment plants and interviewed more than 230 officials, academics and scientists. They also surveyed the nation's 50 largest cities and a dozen other major water providers, as well as smaller community water providers in all 50 states.

    Here are some of the key test results obtained by the AP:

    • Officials in Philadelphia said testing there discovered 56 pharmaceuticals or byproducts in treated drinking water, including medicines for pain, infection, high cholesterol, asthma, epilepsy, mental illness and heart problems. Sixty-three pharmaceuticals or byproducts were found in the city's watersheds.

    • Anti-epileptic and anti-anxiety medications were detected in a portion of the treated drinking water for 18.5 million people in Southern California.

    • Researchers at the U.S. Geological Survey analyzed a Passaic Valley Water Commission drinking water treatment plant, which serves 850,000 people in Northern New Jersey, and found a metabolized angina medicine and the mood-stabilizing carbamazepine in drinking water.

    • A sex hormone was detected in San Francisco's drinking water.

    • The drinking water for Washington, D.C., and surrounding areas tested positive for six pharmaceuticals.

    • Three medications, including an antibiotic, were found in drinking water supplied to Tucson.

    The situation is undoubtedly worse than suggested by the positive test results in the major population centers documented by the AP.

    The federal government doesn't require any testing and hasn't set safety limits for drugs in water. Of the 62 major water providers contacted, the drinking water for only 28 was tested. Among the 34 that haven't: Houston, Chicago, Miami, Baltimore, Phoenix, Boston and New York City's Department of Environmental Protection, which delivers water to 9 million people.

    Some providers screen only for one or two pharmaceuticals, leaving open the possibility that others are present.

    The AP's investigation also indicates that watersheds, the natural sources of most of the nation's water supply, also are contaminated. Tests were conducted in the watersheds of 35 of the 62 major providers surveyed by the AP, and pharmaceuticals were detected in 28.

    Yet officials in six of those 28 metropolitan areas said they did not go on to test their drinking water — Fairfax, Va.; Montgomery County in Maryland; Omaha; Oklahoma City; Santa Clara, Calif., and New York City.

    The New York state health department and the USGS tested the source of the city's water, upstate. They found trace concentrations of heart medicine, infection fighters, estrogen, anti-convulsants, a mood stabilizer and a tranquilizer.

    City water officials declined repeated requests for an interview. In a statement, they insisted that "New York City's drinking water continues to meet all federal and state regulations regarding drinking water quality in the watershed and the distribution system" — regulations that do not address trace pharmaceuticals.

    In several cases, officials at municipal or regional water providers told the AP that pharmaceuticals had not been detected, but the AP obtained the results of tests conducted by independent researchers that showed otherwise. For example, water department officials in New Orleans said their water had not been tested for pharmaceuticals, but a Tulane University researcher and his students have published a study that found the pain reliever naproxen, the sex hormone estrone and the anti-cholesterol drug byproduct clofibric acid in treated drinking water.

    Of the 28 major metropolitan areas where tests were performed on drinking water supplies, only Albuquerque; Austin, Texas; and Virginia Beach; said tests were negative. The drinking water in Dallas has been tested, but officials are awaiting results. Arlington, Texas, acknowledged that traces of a pharmaceutical were detected in its drinking water but cited post-9/11 security concerns in refusing to identify the drug.

    The AP also contacted 52 small water providers — one in each state, and two each in Missouri and Texas — that serve communities with populations around 25,000. All but one said their drinking water had not been screened for pharmaceuticals; officials in Emporia, Kan., refused to answer AP's questions, also citing post-9/11 issues.

    Rural consumers who draw water from their own wells aren't in the clear either, experts say.

    The Stroud Water Research Center, in Avondale, Pa., has measured water samples from New York City's upstate watershed for caffeine, a common contaminant that scientists often look for as a possible signal for the presence of other pharmaceuticals. Though more caffeine was detected at suburban sites, researcher Anthony Aufdenkampe was struck by the relatively high levels even in less populated areas.

    He suspects it escapes from failed septic tanks, maybe with other drugs. "Septic systems are essentially small treatment plants that are essentially unmanaged and therefore tend to fail," Aufdenkampe said.

    Even users of bottled water and home filtration systems don't necessarily avoid exposure. Bottlers, some of which simply repackage tap water, do not typically treat or test for pharmaceuticals, according to the industry's main trade group. The same goes for the makers of home filtration systems.

    Contamination is not confined to the United States. More than 100 different pharmaceuticals have been detected in lakes, rivers, reservoirs and streams throughout the world. Studies have detected pharmaceuticals in waters throughout Asia, Australia, Canada and Europe — even in Swiss lakes and the North Sea.

    For example, in Canada, a study of 20 Ontario drinking water treatment plants by a national research institute found nine different drugs in water samples. Japanese health officials in December called for human health impact studies after detecting prescription drugs in drinking water at seven different sites.

    In the United States, the problem isn't confined to surface waters. Pharmaceuticals also permeate aquifers deep underground, source of 40% of the nation's water supply. Federal scientists who drew water in 24 states from aquifers near contaminant sources such as landfills and animal feed lots found minuscule levels of hormones, antibiotics and other drugs.

    Perhaps it's because Americans have been taking drugs — and flushing them unmetabolized or unused — in growing amounts. Over the past five years, the number of U.S. prescriptions rose 12% to a record 3.7 billion, while non-prescription drug purchases held steady around 3.3 billion, according to IMS Health and The Nielsen Co.

    "People think that if they take a medication, their body absorbs it and it disappears, but of course that's not the case," said EPA scientist Christian Daughton, one of the first to draw attention to the issue of pharmaceuticals in water in the United States.

    Some drugs, including widely used cholesterol fighters, tranquilizers and anti-epileptic medications, resist modern drinking water and wastewater treatment processes. Plus, the EPA says there are no sewage treatment systems specifically engineered to remove pharmaceuticals.

    One technology, reverse osmosis, removes virtually all pharmaceutical contaminants but is very expensive for large-scale use and leaves several gallons of polluted water for every one that is made drinkable.

    Another issue: There's evidence that adding chlorine, a common process in conventional drinking water treatment plants, makes some pharmaceuticals more toxic.

    Human waste isn't the only source of contamination. Cattle, for example, are given ear implants that provide a slow release of trenbolone, an anabolic steroid used by some bodybuilders, which causes cattle to bulk up. But not all the trenbolone circulating in a steer is metabolized. A German study showed 10% of the steroid passed right through the animals.

    Water sampled downstream of a Nebraska feedlot had steroid levels four times as high as the water taken upstream. Male fathead minnows living in that downstream area had low testosterone levels and small heads.

    Other veterinary drugs also play a role. Pets are now treated for arthritis, cancer, heart disease, diabetes, allergies, dementia, and even obesity — sometimes with the same drugs as humans. The inflation-adjusted value of veterinary drugs rose by 8%, to $5.2 billion, over the past five years, according to an analysis of data from the Animal Health Institute.

    Ask the pharmaceutical industry whether the contamination of water supplies is a problem, and officials will tell you no. "Based on what we now know, I would say we find there's little or no risk from pharmaceuticals in the environment to human health," said microbiologist Thomas White, a consultant for the Pharmaceutical Research and Manufacturers of America.

    But at a conference last summer, Mary Buzby — director of environmental technology for drug maker Merck & Co. Inc. — said: "There's no doubt about it, pharmaceuticals are being detected in the environment and there is genuine concern that these compounds, in the small concentrations that they're at, could be causing impacts to human health or to aquatic organisms."

    Recent laboratory research has found that small amounts of medication have affected human embryonic kidney cells, human blood cells and human breast cancer cells. The cancer cells proliferated too quickly; the kidney cells grew too slowly; and the blood cells showed biological activity associated with inflammation.

    Also, pharmaceuticals in waterways are damaging wildlife across the nation and around the globe, research shows. Notably, male fish are being feminized, creating egg yolk proteins, a process usually restricted to females. Pharmaceuticals also are affecting sentinel species at the foundation of the pyramid of life — such as earth worms in the wild and zooplankton in the laboratory, studies show.

    Some scientists stress that the research is extremely limited, and there are too many unknowns. They say, though, that the documented health problems in wildlife are disconcerting.

    "It brings a question to people's minds that if the fish were affected ... might there be a potential problem for humans?" EPA research biologist Vickie Wilson told the AP. "It could be that the fish are just exquisitely sensitive because of their physiology or something. We haven't gotten far enough along."

    With limited research funds, said Shane Snyder, research and development project manager at the Southern Nevada Water Authority, a greater emphasis should be put on studying the effects of drugs in water.

    "I think it's a shame that so much money is going into monitoring to figure out if these things are out there, and so little is being spent on human health," said Snyder. "They need to just accept that these things are everywhere — every chemical and pharmaceutical could be there. It's time for the EPA to step up to the plate and make a statement about the need to study effects, both human and environmental."

    To the degree that the EPA is focused on the issue, it appears to be looking at detection. Grumbles acknowledged that just late last year the agency developed three new methods to "detect and quantify pharmaceuticals" in wastewater. "We realize that we have a limited amount of data on the concentrations," he said. "We're going to be able to learn a lot more."

    While Grumbles said the EPA had analyzed 287 pharmaceuticals for possible inclusion on a draft list of candidates for regulation under the Safe Drinking Water Act, he said only one, nitroglycerin, was on the list. Nitroglycerin can be used as a drug for heart problems, but the key reason it's being considered is its widespread use in making explosives.

    So much is unknown. Many independent scientists are skeptical that trace concentrations will ultimately prove to be harmful to humans. Confidence about human safety is based largely on studies that poison lab animals with much higher amounts.

    There's growing concern in the scientific community, meanwhile, that certain drugs — or combinations of drugs — may harm humans over decades because water, unlike most specific foods, is consumed in sizable amounts every day.

    Our bodies may shrug off a relatively big one-time dose, yet suffer from a smaller amount delivered continuously over a half century, perhaps subtly stirring allergies or nerve damage. Pregnant women, the elderly and the very ill might be more sensitive.

    Many concerns about chronic low-level exposure focus on certain drug classes: chemotherapy that can act as a powerful poison; hormones that can hamper reproduction or development; medicines for depression and epilepsy that can damage the brain or change behavior; antibiotics that can allow human germs to mutate into more dangerous forms; pain relievers and blood-pressure diuretics.

    For several decades, federal environmental officials and non-profit watchdog environmental groups have focused on regulated contaminants — pesticides, lead, PCBs — which are present in higher concentrations and clearly pose a health risk.

    However, some experts say medications may pose a unique danger because, unlike most pollutants, they were crafted to act on the human body.

    "These are chemicals that are designed to have very specific effects at very low concentrations. That's what pharmaceuticals do. So when they get out to the environment, it should not be a shock to people that they have effects," says zoologist John Sumpter at Brunel University in London, who has studied trace hormones, heart medicine and other drugs.

    And while drugs are tested to be safe for humans, the timeframe is usually over a matter of months, not a lifetime. Pharmaceuticals also can produce side effects and interact with other drugs at normal medical doses. That's why — aside from therapeutic doses of fluoride injected into potable water supplies — pharmaceuticals are prescribed to people who need them, not delivered to everyone in their drinking water.

    "We know we are being exposed to other people's drugs through our drinking water, and that can't be good," says Dr. David Carpenter, who directs the Institute for Health and the Environment of the State University of New York at Albany.
  • The Seer
    SBR Posting Legend
    • 10-29-07
    • 10641

    #2
    Cities rarely release water test results

    Cities rarely release water test results

    The Associated Press
    When water providers find pharmaceuticals in drinking water, they rarely tell the public. When researchers make the same discoveries, they usually don't identify the cities involved.
    There are plenty of reasons offered for the secrecy: concerns about national security, fears of panic, a feeling that the public will not understand — even confidentiality agreements.


    AP PROBE: Drugs found in drinking water nationwide

    NYC: Sedative traces found in system that does not filter water
    "That's a really sensitive subject," said Elaine Archibald, executive director of California Urban Water Agencies, an 11-member organization comprised of the largest water providers in California.

    She said many customers "don't know how to interpret the information. They hear something has been detected in source water and drinking water, and that's cause for alarm — just because it's there."

    As The Associated Press documented in a five-month investigation, drinking water provided to at least 41 million people living in 24 major metropolitan areas has tested positive for trace amounts of pharmaceuticals.

    Most Americans probably think they have a good idea of what's being detected in their water. Federal law requires water providers to distribute annual "consumer confidence reports" that reveal levels of regulated contaminants. Providers are not, however, required to tell people if they find a contaminant that is not on a U.S. Environmental Protection Agency list. And there are no pharmaceuticals on the EPA list.

    In Philadelphia, the water department has not informed its 1.5 million users that traces of 56 pharmaceuticals or their byproducts — like the active ingredients in drugs to treat depression, anxiety, high cholesterol, fever and pain — have been detected in the drinking water, and that 63 pharmaceuticals or byproducts had been found in the city's source watersheds.

    Initially balking at the AP's request to provide test results, Philadelphia Water Department spokeswoman Laura Copeland said, "It would be irresponsible to communicate to the public about this issue, as doing so would only generate questions that scientific research has not yet answered. We don't want to create the perception where people would be alarmed."

    New York City water officials declined repeated requests for an interview and waited more than three months before participating in an AP survey, supplying information only after being informed that every other major city in the nation had cooperated.

    The AP learned that the New York state health department and the U.S. Geological Survey detected heart medicine, infection fighters, estrogen, anti-convulsants, a mood stabilizer and the active ingredient in an anti-anxiety medication in the city's watershed upstate. And the city's Department of Environmental Protection ultimately said that it does not test its downstate drinking water.

    Officials in Arlington, Texas, said pharmaceuticals had been detected in source water but wouldn't say which ones or in what amounts, citing security concerns. Julie Hunt, director of water utilities, said to provide the public with information regarding "which, if any, pharmaceuticals or emerging compounds make it through the treatment process can assist someone who wishes to cause harm through the water supply."

    Mayor Robert Cluck later said a trace amount of one pharmaceutical had survived the treatment process and had been detected in drinking water. He declined to name the drug, saying identifying it could cause a terrorist to intentionally release more of it, causing significant harm to residents.

    "I don't want to take that chance," Cluck said. "There is no public hazard and I don't want to create one."

    Ron Rhodes, water treatment plant supervisor in Emporia, Kan., explained why he wouldn't disclose whether his community's source water or drinking water had been tested for pharmaceuticals. "Well, it's because of 9/11. We want everybody to guess."

    How, Rhodes was asked, could it endanger anyone to know if Emporia's water has been screened for traces of pharmaceutical compounds?

    "We're not putting out more information than we have to put out," said Rhodes. "How about that?"

    Milwaukee's water department is an anomaly, posting on its website an 11-page detailed drinking water quality report that includes test results for 450 unregulated contaminants, including pharmaceuticals. While they found minute concentrations of cotinine, a nicotine derivative, they didn't detect hundreds of other contaminants including estrogens and other hormones, acetaminophen and ibuprofen.

    When asked what power the EPA had to require public disclosure when pharmaceutical contamination is discovered in a water provider's supplies, Benjamin H. Grumbles, the agency's assistant administrator for water, said, "We work very closely with utilities across the country and we encourage them to share with their community information they find out about their source water."

    But there's no such requirement if the detected contaminant is not regulated under the Safe Drinking Water Act, he said in response to a question.

    Grumbles was asked how he thought water providers have been responding to the EPA's "encouragement."

    "I think we have more work to do," he said.

    Several hours after the interview, Grumbles issued a statement: "As head of the National Water Program, I will do everything in my authority to make certain that public water suppliers inform their consumers if they detect pharmaceuticals in the drinking water."

    It's not just the water departments that have failed to disclose such information.

    The AP spoke with many scientists, federally funded researchers, university professors and private drinking water experts who have detected pharmaceuticals in drinking water, but would not say where they had obtained their samples.

    Archibald said her organization joined an American Water Works Association Research Foundation study with the understanding that secrecy would be assured.

    "We agreed ahead of time that no specific agency would be mentioned in terms of which place had detections," Archibald said. She insisted that even she didn't have the test results. "It's all being held very carefully. Water agencies were assigned numbers so none of us would even know what was detected in each other's water."

    Robert Renner, the foundation's executive director, said AWWARF study participants are routinely promised anonymity. "Being involved in a study, they don't want this information blown out all over," he said.

    Citing confidentiality agreements, he declined to name the 20 different drinking water treatment plants around the U.S. where pharmaceuticals have been detected in water heading to more than 10 million people.

    "It's a hard topic to talk about without creating fear in the general public," Renner said.

    Some said those fears could lead to much larger problems than the actual contamination.

    Doctors "don't want people to be afraid to take their medicine because of environmental concerns," said Virginia Cunningham, an environmental executive for drug maker GlaxoSmithKline PLC.

    Utilities also generally only allow scientists to test their water if they ensure confidentiality. In order for research to progress, scientists "need the confidence of utilities and other public/private stakeholders to allow us access to waters which we can study without any negative implications for those stakeholders," said Howard Weinberg, an environmental chemist at University of North Carolina. "Without this confidence, such research could not be undertaken."

    John Vargo, program manager at the University of Iowa's University Hygienic Laboratory, said he found traces of pharmaceuticals in the finished drinking water of several major Midwestern cities but, under terms of those contracts, he could not disclose their identity.

    Peter Rogers, Harvard University professor of environmental engineering, said improvements in detection techniques could help fuel fears among the general public.

    "We're chasing this down to molecular-sized measurements, so the more you look, the more you find," said Rogers. "I think the government and utilities are quite right to be very skittish about telling people their results. People will claim it is causing all sorts of problems. If I were a water utility, I would stop those measurements right away because if you measure something, it will get out, and people will overreact. I can just imagine a whole slew of lawsuits."
    Comment
    • Willie Bee
      SBR Posting Legend
      • 02-14-06
      • 15726

      #3
      Hey, maybe they'll start finding Viagra and Cialis in tap water and I won't have to worry about that expense when I'm on a fixed retirement income in a few years.

      Report fails to mention much about the crap that gets into the water chain from livestock, especially how the runoff in some ag regions has already screwed up some previously fine fishing holes across this country.
      Comment
      • The Seer
        SBR Posting Legend
        • 10-29-07
        • 10641

        #4
        Originally posted by Willie Bee
        Hey, maybe they'll start finding Viagra and Cialis in tap water and I won't have to worry about that expense when I'm on a fixed retirement income in a few years.

        Report fails to mention much about the crap that gets into the water chain from livestock, especially how the runoff in some ag regions has already screwed up some previously fine fishing holes across this country.
        I read one report where they thought fish weren't breeding like they should and because of the drugs in the water. Maybe they can't live off of bull piss and meth.
        Comment
        • Sportsgirl
          SBR MVP
          • 09-10-06
          • 4493

          #5
          Originally posted by The Seer
          MORE: Sedative traces found in water.
          I am feeling really sleepy today.
          Comment
          • RageWizard
            SBR MVP
            • 09-01-06
            • 3008

            #6
            Hey SEER, War and Peace may be shorter than you origianal post. Seriously though, this is the reason I like to have beer instead of water. If I were allowed to drink at work, I would never drink water.
            Comment
            • Robyn
              SBR Hall of Famer
              • 02-05-08
              • 9681

              #7
              This story doesn't surpise me one bit. It is legal to dispose of narcotics and medication by flushing it down the toilet. Scary, huh?
              Comment
              • WestsidePete
                SBR Hall of Famer
                • 07-19-07
                • 8049

                #8
                great ...so all of us driving in LA are f*cked up on drugs...no wonder when it rains everyone freaks out and people have road rage....so alcohol is safer than water??
                Comment
                • Robyn
                  SBR Hall of Famer
                  • 02-05-08
                  • 9681

                  #9
                  Or stick to drinking bottled water.
                  Comment
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