QB vs Opposing Defense in your lineup?

[onlooker]

I have really never gave this any thought. Not sure I have ever did this. On first thought, I would think it would be bad.

Is it good or a bad thing to have a Defense in your lineup that is going against your starting QB? Or does it even matter?

For example, this could be my starting QB and Defense in Week 7:

C.Ponder
Cardinals Defense

Good. Bad. Doesn't Matter?

[Speedy88]

Just play the guys that will give you the highest score. However, if your going to watch the game, it might drive you crazy. I try to stay away from starting defenses that go up against my QB, but that is just because I watch the games.