UFC 321 Parlay Picks & Predictions for +950 Odds

Our UFC picks highlight the most reliable styles on the card to come up with my best UFC 321 parlay picks. Today's event takes place at Etihad Arena in Abu Dhabi, where heavyweight champion Tom Aspinall (-400 betting favorite) meets Ciryl Gane in the main event. The lineup also features a strawweight title rematch between Mackenzie Dern and Virna Jandiroba, plus strong supporting bouts across divisions.

All my picks on the way to a +950 parlay are on the main card, which gets under at 2 p.m. ET (pay-per-view). A winning $10 ticket at bet365 pays $95 profit if all four cash.

💰 Best UFC 321 parlay picks today

🔥 Best UFC 321 parlay picks

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1️⃣ Tom Aspinall vs. Ciryl Gane Under 1.5 rounds (-120)

Tom Aspinall has never seen Round 2 in his UFC career. All nine of his bouts ended inside a round and a half, whether by knockout or submission. He overwhelmed Alexander Volkov in under four minutes and stopped Curtis Blaydes with a jab inside one.

Ciryl Gane often fights long, but Aspinall’s speed and aggression make early violence the likeliest outcome. The champion’s first real test since knee surgery should still produce another quick finish.

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2️⃣ Umar Nurmagomedov by decision vs. Mario Bautista (-175)

Nurmagomedov’s game is control and consistency. He averages over three takedowns per fifteen minutes with precise distance striking to set them up. Mario Bautista is durable, having gone the distance with names like Ricky Simón and José Aldo, so a finish is less probable. Expect Umar to dictate pace, rack up mat control, and sweep the scorecards through positional dominance rather than submissions.

3️⃣ Aleksander Rakic to defeat Azamat Murzakanov (-110)

Rakic owns major advantages in height, reach, and experience. Murzakanov has fought only three times in the past three years, each against lower-tier opponents. This is a big step up. Rakic’s straight punches and takedown defense should keep the fight at range, where his 78-inch reach can dictate rhythm. If he stays patient and avoids the pocket brawls Murzakanov prefers, his precision and volume win out.

4️⃣ Virna Jandiroba vs. Mackenzie Dern: Fight to go the distance? Yes (-110)

Their first meeting between Mackenzie Dern and Virna Jandiroba at UFC 256 went the full fifteen minutes, and the same stylistic balance remains. Both are elite grapplers who respect each other’s submission skills, which limits risk-taking.

Jandiroba averages under two significant strikes per minute and leans on control, while Dern’s measured pace favors steady exchanges rather than chaos. Their shared toughness and mutual respect for the ground game point to another close decision rather than a finish.

📺 How to watch UFC 321

• Date: Saturday, Oct. 25
• Time: 10 a.m. ET (prelims); 2 p.m. ET (main card)
• Location: Etihad Arena (Abu Dhabi, United Arab Emirates)
• TV: ESPN+ (prelims); Pay-per-view (main card)