Islam Makhachev vs. Jack Della Maddalena Prediction & Odds: Who'll Win UFC 322 New York?
My Islam Makhachev vs. Jack Della Maddalena prediction for UFC 322 focuses on Saturday’s main event, set for Nov. 15 at Madison Square Garden in New York City. The reigning lightweight champion moves up to welterweight as the -275 favorite at bet365, while Della Maddalena enters as a +225 underdog looking to spoil his debut.
We’re backing Makhachev as part of our UFC 322 predictions to win in his first welterweight appearance, using his trademark grappling and relentless pressure to smother Della Maddalena’s slick boxing and control the fight from start to finish.
✅ Islam Makhachev vs. Jack Della Maddalena Predictions: UFC 322 expert picks
See all of our UFC picks for this weekend's fights.
💵 Islam Makhachev vs. Jack Della Maddalena best bets
- Pick to win: Islam Makhachev (-275 via bet365) ⭐⭐⭐⭐
- Best bet: Makhachev by Submission (+200 via bet365) ⭐⭐⭐
🥊 Islam Makhachev vs. Jack Della Maddalena fight preview
Islam Makhachev’s grappling has defined his reign at lightweight, smothering world-class opponents with elite positional control and fight IQ. His transition to welterweight brings intrigue, but his skill set should still translate, especially against a striker like Della Maddalena, who prefers space to operate. Makhachev’s chain wrestling and top control remain among the best in MMA, giving him a decisive edge if the fight hits the mat.
At -275 odds, Makhachev’s implied win probability sits at 73.3%, returning a $3.64 profit on a $10 wager.
💰 Islam Makhachev vs. Jack Della Maddalena best bet: UFC 322
Check our best UFC betting sites for the latest odds for this fight.
🔥 Best bet: Makhachev by submission (+200)
Makhachev’s path to victory still runs through his relentless grappling. Jack Della Maddalena represents a composed, technical striker with excellent takedown defense - but Islam is a different challenge entirely. His ability to chain takedowns, pressure through the clinch, and dominate from top position makes him a submission threat every time he lands on the mat.
JDM’s defensive instincts and toughness should help him survive early, but over 25 minutes, Makhachev’s pace and positional awareness typically overwhelm even elite opponents. Expect the Australian to fend off a few shots early before the Dagestani champion breaks through and finds a finish on the ground.
At +200 odds, a Makhachev submission implies a 33.3% chance of hitting, with a $20 profit on a $10 stake.
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📊 Della Maddalena vs. Makhachev odds
Odds via bet365 subject to change.
| Outcome | Jack Della Maddalena | Islam Makhachev |
|---|---|---|
| Win outright | +225 | -275 |
| Win by KO/TKO/DQ | +400 | +600 |
| Win by Decision | +650 | +187 |
| Win by Submission | +2500 | +200 |
| Draw | +8000 | +8000 |
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🆚 Makhachev vs. Della Maddalena tale of the tape
| Category | Islam Makhachev | Jack Della Maddalena |
|---|---|---|
| Age | 34 | 29 |
| Height | 5’10” | 5’11” |
| Weight | 170 lbs | 170 lbs |
| Reach | 70” | 73” |
| Record | 27-1-0 | 18-2-0 |
| Wins by KO | 5 (19%) | 12 (67%) |
| Wins by submission | 13 (48%) | 2 (11%) |
| Wins by decision | 9 (33%) | 4 (22%) |
📺 How to watch UFC 322: Makhachev vs. Della Maddalena
Date: Saturday, November 15, 2025
Time: 10:00 p.m. ET (main card)
Location: Madison Square Garden (New York City, NY)
TV: ESPN+ PPV (U.S.), Sportsnet / UFC PPV (Canada)
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