⚽ Manchester United vs. Leeds Prediction, Picks & Odds for Monday's Premier League Match

Manchester United aim to stay perfect at home under new coach against Leeds in Roses Derby.
Benjamin Sesko of Manchester United celebrates with Matheus Cunha as we make our best Manchester United vs. Leeds prediction.
Pictured: Benjamin Sesko of Manchester United celebrates with Matheus Cunha as we make our best Manchester United vs. Leeds prediction. Photo by Mark Cosgrove/News Images
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Monday Night Football features the one of the Premier League's storied rivalries, as my Manchester United vs. Leeds prediction breaks down the Roses derby between two teams trending in different directions.

Manchester United are the lopsided -160 betting favorite, as the Red Devils try to seal a spot in the Champions League. They're up against a spiraling Leeds outfit that has +400 odds for the match.

My Premier League best bets also include a Manchester United player to target for an assist. The action from Old Trafford begins at 3 p.m. ET on USA Network.


⚽ Manchester United vs. Leeds predictions

See our experts' soccer picks based on the latest Premier League odds.

Predictions Best odds Bet size Confidence 
Manchester United ML -160 via DraftKings 1.5 units -> 0.94 units ⭐⭐⭐⭐
Over 2.5 -138 via bet365 1 unit -> 0.7 units ⭐⭐⭐
Both teams to score -140 via DraftKings 1.5 units -> 1.1 units ⭐⭐⭐⭐
Matheus Cunha anytime goal-scorer +230 via DraftKings 0.5 units -> 1.2 units ⭐⭐⭐

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💰 Manchester United vs. Leeds best bet

Check out all of our soccer betting analysis and expert predictions this season.

Manchester United ML (-160)

It's hard to pick anything other than a Manchester United win for Monday's game. The Red Devils have been incredible at home, sporting a perfect record at Old Trafford since Michael Carrick took charge as manager.

Manchester United have won all five of their home games since Carrick's appointment on Jan. 13, and have earned 23 points from a possible 30 in their Premier League games.

It also helps that United have had plenty of rest for this fixture, with the team's last game coming 23 days ago. Conversely, Leeds played 120 minutes last weekend in a game that went to extra time and penalties.

Score prediction: Manchester United 2, Leeds 1


🔥 Best Manchester United vs. Leeds prop bet

Both teams to score (-140)

Manchester United's attack has stepped up in recent months, but their defense has some question marks. The club has conceded 43 goals in 31 games and could be susceptible to conceding Monday without their top center-back duo.

While there's optimism that Lisandro Martinez will return to the starting XI after a five-game absence with a calf injury, the Red Devils will be without Harry Maguire due to suspension.

Although we expect Manchester United to score at home amid a five-game run where they've recorded two goals per game, we also expect Leeds to find the back of the net in their desperate bid to avoid relegation.


🙌 Best Manchester United vs. Leeds goal-scorer prediction

Matheus Cunha, Manchester United (+230) 

Despite not playing a competitive match in almost one month, we expect Matheus Cunha to strengthen the club's bid to seal a Champions League place for next season with a goal against Leeds.

After a slow start, Cunha opened 2026 in bright form, scoring against Leeds' poor defense at Elland Road. His form and lethal finishing makes him a prime candidate to punish Leeds' defense again.

Cunha scored in back-to-back games before the most recent international break, and netted another for Brazil. He has seven Premier League goals in his first season with United.


🚀 Manchester United vs. Leeds same-game parlay

We're expecting Manchester United to pick up where they left off in March and continue their winning ways. This correlates well with forward Matheus Cunha recording a goal. Meanwhile, United's shaky defense can't be trusted, so picking BTTS seems like the logical route.

💵 Manchester United vs. Leeds SGP picks

  • Manchester United ML (-160)
  • Both teams to score (-140)
  • Matheus Cunha anytime goal-scorer (+230)

Best odds: +600 via DraftKings (1 unit -> 6 units)


⚖️ How I'm handicapping Manchester United vs. Leeds

Michael Carrick's influence since he was appointed head coach can't be ignored. The team looks rejuvenated compared to the side that struggled tactically under former boss Ruben Amorim, who was dismissed late last year.

Carrick has breathed new life into a United team that's surged up the table to move into third place with seven games remaining.

Leeds' recent success in the FA Cup only temporarily masked concerns over the club's position near the bottom of the table. While they'll hope the emotional victory over West Ham in the FA Cup can propel them to a positive away performance, the task of taking down an in-form Manchester United side seems too great for coach Daniel Farke's men.

Manchester United vs. Leeds key stats

Manchester United Leeds
Goals for 56 37
Goals against 43 48
Shots on target 178 120
XG 53.24 43.07

📊 Manchester United vs. Leeds odds

Manchester United have shifted from a home favorite to a stronger position with bookmakers for various reasons. The injury crisis at Leeds is among the main reasons, as Monday's visitors will be missing a handful of regulars. Manchester United's extended rest and Leeds'  penalty win in the FA Cup have also contributed to fortifying the host's odds.


🆚 Manchester United vs. Leeds projected lineups

Here are Monday's projected lineups for Manchester United vs. Leeds ; lineups subject to change:

Manchester United Leeds
Lammens Darlow
Dalot Bogle
Martinez Bijol
Yoro Struijk
Shaw Justin
Casemiro Gruev
Mainoo Ampadu
Amad Gudmundsson
Fernandes Tanaka
Cunha Calvert-Lewin
Mbeumo Okafor

📈 Manchester United vs. Leeds betting trends

Manchester United Statistic Leeds
15-10-6 (3rd place) Season record 7-12-12 (15th place)
50-38-26 H2H record 26-38-50
W-W-L-W-D Last 5 games D-L-L-D-D
Draw 2-2 vs. Bournemouth Previous result Won 2-2 vs. Crystal Palace (on penalties)
Manchester United haven't lost in 18 league games against Leeds. Key stat Leeds are at risk of losing both league games against Manchester United for the first time since 1994-95.

Based on recent form, it could be a long day at the office for Leeds United.

The club's Premier League record is in danger of getting worse if Leeds can't cope without their missing players against an inspired Manchester United team hoping to impress supporters at Old Trafford.

Although United will be without suspended Harry Maguire, they have the depth to cope with his absence. Meanwhile Leeds will struggle to replace the impact of missing players such as Daniel James and Joe Rodon.


🌤️ Manchester United vs. Leeds weather

Rain is expected around kick-off before clear and cool conditions later in the night. Temperatures are expected to drop from the high 40s to the low 40s, with light winds. The damp surface to begin the game could result in the ball moving faster in the first half compared to the second.


📺 How to watch Manchester United vs. Leeds

  • Date: Monday, April 13
  • Kickoff: 3 p.m. ET
  • Location: Old Trafford (Manchester, England)
  • TV: USA Network

❓ Manchester United vs. Leeds FAQ

Who is favored to win Manchester United vs. Leeds ?

Manchester United are a -160 betting favorites against Leeds on Monday.

Who is the best Manchester United vs. Leeds bet?

The best bets for Manchester United vs. Leeds include Matheus Cunha to score (+230).

Where to watch Manchester United vs. Leeds in the US and Canada?

You can watch Manchester United vs. Leeds on USA Network in the United States, or stream the game on FuboTV in Canada.