Manchester City vs. Leverkusen Prediction & Odds: Champions League Betting Preview for Tuesday
Last Updated: November 24, 2025 2:37 PM EST • 3 minute read X Social Google News Link
My Manchester City vs. Bayer Leverkusen prediction looks at how Pep Guardiola’s squad can maintain its momentum in the Champions League with a home win at Etihad Stadium.
Manchester City are the deserving favorite at -450 to beat Leverkusen (+1100), and my Champions League best bets analyze who will step up Tuesday at 3 p.m ET on Paramount+ to deliver a fourth Champions League win in five games for City.
✅ Manchester City vs. Leverkusen prediction & expert picks
See all of our experts' soccer picks this week.
💵 Best Manchester City vs. Leverkusen bets
- Game prediction: Manchester City -1.5 (-170 via DraftKings) ⭐⭐⭐⭐⭐
- Over/Under pick: Under 3.5 (-111 via bet365) ⭐⭐⭐⭐
- Best prop bet: Erling Haaland first scorer (+195 via DraftKings) ⭐⭐⭐
⚽ Manchester City vs. Leverkusen preview & score prediction
Manchester City barely get any time to process what went wrong in their last game.
But a short break might actually be good for the English club, as I predict City will beat Bayer Leverkusen by two goals or more.
Man City out for revenge
A date with Bayer Leverkusen, who have struggled in the Champions League, could be just what the Premier League side needs to get back on track after a demoralizing defeat to Newcastle.
The loss was a setback in their bid to keep up with leaders Arsenal. But Manchester City get a chance to accomplish the same goal (they’re two points back of first-place Arsenal in the Champions League) on Tuesday at Etihad Stadium.
It’s no secret that Leverkusen have been regressing since winning the Bundesliga in 2024, but performances in the league this year suggest the third-placed team is on the rise.
Unfortunately for Leverkusen, they’ll face a City team that’s feasted on German opponents over the years. City have won their last 13 games against German squads, including a 4-1 victory over Dortmund in their last Champions League outing.
A winning $10 bet on City earning a two-plus goal victory nets a profit of $5.88 at DraftKings
Score prediction: Manchester City 3, Bayer Leverkusen 0
🆚 Manchester City vs. Leverkusen matchup to watch
Erling Haaland vs. Leverkusen’s defense
It’s time to stop being cute and bet on the guy everyone’s backing to score.
Erling Haaland was quiet after a pair of early chances in City’s 2-1 away loss to Newcastle over the weekend. But I expect him to come out flying Tuesday and score the first goal of the game.
After scoring in all five of Manchester City’s Champions League games, Haaland will like his chances of stretching it to six when he goes up against a Leverkusen side that’s conceded over two goals per game in the competition.
Haaland, who has logged 19 goals in 16 games, has been the first scorer in six of his last nine appearances in all competitions.
A successful $10 bet at DraftKings delivers a profit of $19.50.
Best prop bet: Erling Haaland first scorer (+195 via DraftKings)
📊 Manchester City vs. Leverkusen odds
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📈 Manchester City vs. Leverkusen betting trends & recent form
| Host | Statistic | Visitor |
| 3-1-0 | Season record | 1-2-1 |
| NA | H2H record | NA |
| W-D-W-W | Last 5 games | D-D-L-W |
| Win 4-1 vs. Dortmund | Previous result | Win 1-0 at Benfica |
| Manchester City have won their last 13 home games against German opposition | Key stat | Leverkusen have lost eight of their last 10 Champions League away games against English opposition. |
🌤️ Manchester City vs. Leverkusen weather
There’s no rain in the forecast, but it'll be chilly at kickoff with the temperature expected to be around 37 degrees. The weather shouldn’t affect either side since both teams have competed in similar conditions recently.
📺 How to watch Manchester City vs. Leverkusen
- Date: Tuesday, Nov. 25
- Kickoff: 3 p.m. ET
- Location: Etihad Stadium, Manchester
- TV: Paramount+
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Gordon Brunt