Man City vs. Leverkusen Prediction - Today's Champions League Expert Picks, Preview & Odds

Last weekend's action didn't provide a good result for Man City on the road, but maybe a return to the comfy confines of the Etihad will get Pep's side back in the win column. My Man City vs. Leverkusen prediction examines whether the club can move on from Premier League defeat and keep up its Champions League momentum when the action gets underway at 3 p.m. ET (Paramount+).

Man City is trading as a -450 betting favorite, so a stumble here would be surprising. My Champions League best bets pick out a familiar name to shine as the Citizens look to pick up a fourth win in five tries.

✅ Man City vs. Leverkusen prediction & expert picks

See all of our experts' soccer picks this week.

⚽ Man City vs. Leverkusen preview & score prediction

Man City barely get any time to process what went wrong in their last game.

But a short break might actually be good for the English club, as I predict City will beat Bayer Leverkusen by two goals or more.

Man City out for revenge

A date with Bayer Leverkusen, who have struggled in the Champions League, could be just what the Premier League side needs to get back on track after a demoralizing defeat to Newcastle. 

The loss was a setback in their bid to keep up with leaders Arsenal. But Man City get a chance to accomplish the same goal (they’re two points back of first-place Arsenal in the Champions League) on Tuesday at Etihad Stadium.

It’s no secret that Leverkusen have been regressing since winning the Bundesliga in 2024, but performances in the league this year suggest the third-placed team is on the rise. 

Unfortunately for Leverkusen, they’ll face a City team that’s feasted on German opponents over the years. City have won their last 13 games against German squads, including a 4-1 victory over Dortmund in their last Champions League outing. On the note of Dortmund, we have a play on their game in our Champions League predictions for Matchday 5.  

A winning $10 bet on City earning a two-plus goal victory nets a profit of $5.88 at DraftKings

Score prediction: Man City 3, Bayer Leverkusen 0

🆚 Man City vs. Leverkusen matchup to watch

Erling Haaland vs. Leverkusen’s defense

It’s time to stop being cute and bet on the guy everyone’s backing to score.

Erling Haaland was quiet after a pair of early chances in City’s 2-1 away loss to Newcastle over the weekend. But I expect him to come out flying Tuesday and score the first goal of the game.

After scoring in all five of Man City’s Champions League games, Haaland will like his chances of stretching it to six when he goes up against a Leverkusen side that’s conceded over two goals per game in the competition.

Haaland, who has logged 19 goals in 16 games, has been the first scorer in six of his last nine appearances in all competitions.

A successful $10 bet at DraftKings delivers a profit of $19.50.

Best prop bet: Erling Haaland first scorer (+195 via DraftKings)

📊 Man City vs. Leverkusen odds

See live Champions League odds for every game.

📈 Man City vs. Leverkusen betting trends & recent form

🌤️ Man City vs. Leverkusen weather

There’s no rain in the forecast, but it'll be chilly at kickoff with the temperature expected to be around 37 degrees. The weather shouldn’t affect either side since both teams have competed in similar conditions recently.

📺 How to watch Man City vs. Leverkusen

• Date: Tuesday, Nov. 25
• Kickoff: 3 p.m. ET
• Location: Etihad Stadium, Manchester, England
• TV: Paramount+