NFL Predictions Week 1: Best Bets & Odds Tonight for Monday Night Football

Last Updated: September 8, 2025 5:19 PM EDT • 2 minute read X Social Google News Link

After a sensational start to the 2025 season, we've gathered our best NFL predictions for the final game of Week 1 tonight on Monday Night Football between the Minnesota Vikings and Chicago Bears. Our NFL picks have you covered for Vikings vs. Bears in the Week 1 finale at Soldier Field in Chicago.
🏈 NFL predictions for Week 1
Here are all of our NFL expert picks for Week 1, which we'll update throughout the week based on the odds at our best sports betting sites.

💰 NFL odds & expert picks: Week 1
Live NFL odds for every Week 1 game; updated in real time. Expert picks added throughout the week.
📊 Vikings vs. Bears odds
- Date: Monday, Sept. 8
- Kickoff: 8:15 p.m. ET
- Location: Soldier Field (Chicago, IL)
- How to watch: ABC
🔮 Vikings vs. Bears prediction: Bears to win (+102)
Here's an excerpt from our Vikings vs. Bears prediction on why Mike Spector is backing the Bears moneyline on Monday Night Football:
"Williams’ increased success in year two starts with an improved offensive line. He was sacked 68 times last season, tied for the third-most in NFL history. To address that, the team traded for guards Joe Thuney (17 starts last year) and Jonah Jackson (four starts), and added center Drew Dalman (nine starts).
Johnson’s influence should also make a world of difference in Williams’ progression. In his time as Lions offensive coordinator, Detroit had a top-five offense in all three seasons.
Furthermore, in terms of yards per play under Johnson, the Lions ranked third overall, third on plays with motion at the snap, and third on play action. He brings his expertise to a talented Bears roster that ranked 22nd or worse in all of those metrics last year."
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