Vikings vs. Chargers Prediction for Thursday Night Football: TNF Week 8
Last Updated: October 23, 2025 6:06 PM EDT • 3 minute read X Social Google News Link
NFL Week 8 kicks off tonight with Thursday Night Football, and my Vikings vs. Chargers prediction expect a low-scoring affair to open our NFL predictions for Week 8.
My NFL picks target the Chargers to win and cover the spread while offering a play on the total. Los Angeles is a 3-point home favorite ahead of kickoff at 8:15 p.m. ET from SoFi Stadium in Inglewood, Calif. (Prime Video).
🏈 Vikings vs. Chargers prediction: Thursday Night Football
NFL expert picks for Thursday Night Football; NFL odds subject to change.
- Spread prediction: Chargers -3 (-120 via FanDuel) ⭐⭐⭐
- Over/Under pick: Under 44.5 (-108 via DraftKings) ⭐⭐⭐
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🆚 Who will win Vikings vs. Chargers tonight?
Backing the Chargers to win by at least four points boils down to having more confidence in Justin Herbert than whoever Vikings head coach Kevin O'Connell throws under center. Sean Tomlinson has Herbert making an impact early with his first touchdown scorer predictions.
Score prediction: Chargers 24, Vikings 20
✅ Vikings vs. Chargers best bet for TNF
Track the latest NFL scores for line movement and matchup info.
⚡️ Under 44.5 (-108) ⭐⭐⭐
Carson Wentz and J.J. McCarthy are listed as questionable, both dealing with injuries. Initial reports suggested McCarthy will need another week, while Wentz is dealing with a shoulder issue.
The more probable outcome is that Wentz will line up under center. That won't fill Vikings fans with confidence, as, according to PFF, he has the worst rating of any quarterback with at least four starts. While he's only started two games, McCarthy's rating is even worse.
The Chargers' defense has been terrible over the last three weeks, conceding an average of 30.7 points per game. However, the Vikings offense isn't any better, averaging 18.8 points per game if you exclude the 48-point outlier against the lowly Cincinnati Bengals.
They have the sixth-worst offensive DVOA and haven't scored more than 22 points in three games.
Wentz has thrown four picks in the last three games, two of which to the Philadelphia Eagles in Week 6, where he also fumbled. Meanwhile, Herbert has struggled to cope with his makeshift offensive line. He tossed six interceptions in the last five games and has been sacked 20 times overall, tied for the fifth-most.
Our Dustin Saracini has Chargers QB Justin Herbert having a much better day than Wentz with his Vikings vs. Chargers player prop bets. Esten McLaren's anytime touchdown scorer predictions look at three players who could find the end zone tonight.
That's an ominous thought against a Minnesota Vikings team with the second-highest blitz rate (38.9%). Of the best sports betting sites, DraftKings offers the best price (-108) for the Under on the 44.5-point total, where a winning $10 bet will profit $9.26.
💡 More Vikings vs. Chargers expert picks
- Vikings vs. Chargers prediction
- Vikings vs. Chargers player props
- Vikings vs. Chargers same-game parlay
- Vikings vs. Chargers anytime touchdown scorer predictions
- Vikings vs. Chargers first touchdown scorer predictions
- Vikings vs. Chargers expert picks
📊 Vikings vs. Chargers odds tonight
Latest Thursday Night Football odds updated live in real time.
📺 How to watch Thursday Night Football: Vikings vs. Chargers
- Date: Thursday, Oct. 23
- Kickoff: 8:15 p.m. ET
- Where: SoFi Stadium (Inglewood, Calif.)
- TV: Prime Video
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