Thursday Night Football Odds & Schedule 2025: Week 2 Betting Lines for Commanders vs. Packers
Though the reigning Super Bowl champion Philadelphia Eagles host the rival Dallas Cowboys on Thursday, Sept. 4, to kick off the 2025 NFL season, Thursday Night Football won't have its first true broadcast until Week 2, when the Washington Commanders visit the Green Bay Packers.
Green Bay is a 2.5-point betting favorite by the latest Thursday Night Football odds, with the Over/Under set at 48.5.
Every game of the league's Thursday Night Football schedule - from Week 2 through Christmas night (and including Black Friday) - will be broadcast on Prime Video. That's 16 games throughout the NFL's regular season.
📊 TNF Week 2 odds: Commanders vs. Packers (-2.5)
The Packers opened as 1.5-point betting favorites across our best NFL betting sites for this Week 2 affair. That line has shifted further toward the TNF hosts following training camps and preseason, and Green Bay is now a 2.5-point favorite. The Over/Under has held steady at 48.5 points.
These Thursday Night Football lines will move following the NFL's opening Week 1. Washington a 6.5-point home favorite against the New York Giants in Week 1, and Green Bay is favored by 1.5 points against the visiting Detroit Lions.
Live Thursday Night Football odds: Week 2
🔮 Thursday Night Football prediction
Stay tuned for our Thursday Night Football prediction between the Commanders and Packers ahead of their Week 2 meeting at Lambeau Field in Green Bay, Wisc., on Prime Video.
🗓️ Thursday Night Football 2025 schedule
Opening Thursday Night Football odds for the 2025 season regular season are via DraftKings.
| Week | Matcup | Opening pread | Opening Over/Under |
|---|---|---|---|
| 2 (Sept. 11) | Commanders vs. Packers | Packers -1.5 | 48.5 |
| 3 (Sept. 18) | Dolphins vs. Bills | Bills -8.5 | 48.5 |
| 4 (Sept. 25) | Seahawks vs. Cardinals | Cardinals -2.5 | 46.5 |
| 5 (Oct. 2) | 49ers vs. Rams | Rams -1.5 | 47.5 |
| 6 (Oct. 9) | Eagles vs. Giants | Eagles -7 | 43.5 |
| 7 (Oct. 16) | Steelers vs. Bengals | Bengals -4.5 | 46.5 |
| 8 (Oct. 23) | Vikings vs. Chargers | Chargers -3 | 44.5 |
| 9 (Oct. 30) | Ravens vs. Dolphins | Ravens -5.5 | 47.5 |
| 10 (Nov. 6) | Raiders vs. Broncos | Broncos -6.5 | 43.5 |
| 11 (Nov. 13) | Jets vs. Patriots | Patriots -5.5 | 42.5 |
| 12 (Nov. 20) | Bills vs. Texans | Bills -3.5 | 46.5 |
| 13 (Nov. 28 - Black Friday) | Bears vs. Eagles | Eagles -7 | 46.5 |
| 14 (Dec. 4) | Cowboys vs. Lions | Lions -6 | 48.5 |
| 15 (Dec. 11) | Falcons vs. Buccaneers | Buccaneers -5.5 | 47.5 |
| 16 (Dec. 18) | Rams vs. Seahawks | Rams -1.5 | 44.5 |
| 17 (Dec. 25 - Christmas) | Broncos vs. Chiefs | Chiefs -4.5 | 44.5 |
🧠 Thursday Night Football betting tips
Mind the shorter week
The majority of teams participating in Thursday Night football will be getting just four days between games – and that isn't much time at all to prepare. Teams dealing with personnel or coaching changes or key injuries could be at a major disadvantage. And while those factors are baked into the odds, it's still an element worth your research time.
Expect a slow start
Thursday Night Football may have largely ditched its long-time reputation of being a snoozefest last season. Teams averaged 23.7 points per game last season on Thursday night.
However, a few inflated outputs boosted that number. The Chicago Bears dropped 40 points on the Washington Commanders in Week 5; the Dallas Cowboys put up 41 points on the Seattle Seahawks in Week 13; and the Las Vegas Raiders erupted for 63 points in an embarrassment of the Los Angeles Chargers in Week 15.
Home-field advantage? Not ATS
There are trends that make sense, and then there's the NFL's Thursday Night Football point spread trend, which most certainly does not.
Road teams have been surprisingly potent in recent years despite playing in hostile territory on a short week, going 30-31 SU and 38-22-1 ATS in TNF contests from 2019 through the 2023 regular season.
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❓Thursday Night Football FAQs
Who is favored on Thursday Night Football this week?
The Green Bay Packers are 2.5-point betting favorites at home against the Washington Commanders for Thursday Night Football in Week 2.
How do I watch Thursday Night Football?
With the exception of the NFL 2025 regular-season opener Sept. 4 (which will air on NBC), all Thursday Night Football games can be found exclusively on Prime Video.
Who are the announcers on Thursday Night Football?
Al Michaels and Kirk Herbstreit are the Thursday Night Football broadcasters on Prime Video. Kaylee Hartung is the sideline reporter, and Terry McAulay is the rules analyst.
This broadcast crew has been together since 2022.
Which team will play the most Thursday Night Football games in 2025?
The Bills, Rams, Seahawks, Eagles, and Broncos will all play two Thursday Night Football games this season, though one of the Eagles' TNF broadcasts will actually be on Black Friday,
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