Thursday Night Football Odds & Predictions Week 14: Cowboys vs. Lions Betting Lines

The Thursday Night Football odds for NFL Week 14 list the Cowboys as the 3.5-point underdog on the spread, with an Over/Under of 54.5 for TNF on Prime Video.
Detroit Lions wide receiver Jameson Williams (1) scores a touchdown as we look at the Thursday Night Football odds for Week 14
Pictured: Detroit Lions wide receiver Jameson Williams (1) scores a touchdown as we look at the Thursday Night Football odds for Week 14. Photo by David Reginek-Imagn Images.
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The weekly Prime Video broadcast returns to its usual spot for Week 14, and will feature an NFC showdown with the Detroit Lions (7-5) the slight home favorite against the Dallas Cowboys (6-5-1). The Lions are favored by 3.5 points with both teams having one week of rest after Detroit lost and Dallas won on Thanksgiving.

The Over/Under for the 8:15 p.m. ET kickoff at Ford Field in Detroit is set at 54.5 points - the highest total by the NFL Week 14 odds.


📊 TNF odds Week 14: Cowboys vs. Lions (-3.5)

This spread would be a lot more lopsided if Thanksgiving had played out differently for either team. The Cowboys continue to push toward an unlikely playoff spot following a surprise win over the Kansas City Chiefs, and the Lions fell to the rival Green Bay Packers at home on Thanksgiving.

The betting total is the main attraction here as the highest line of Week 14.

Live Cowboys vs. Lions odds

Our NFL odds update in real time and show the best line and odds for either side of the spread, Over/Under, and moneyline.


🔮 Thursday Night Football predictions: Cowboys vs. Lions

Stay tuned for our expert NFL predictions for Thursday Night Football this week between the Cowboys and Lions, as part of our Week 14 NFL picks.


📜 Thursday Night Football results

Week Matchup Spread outcome Over/Under outcome
2 Commanders vs. Packers Packers -3.5 Under 47.5
3 Dolphins vs. Bills Dolphins +11.5 Over 50.5
4 Seahawks vs. Cardinals Seahawks -1.5 Under 43.5
5 49ers vs. Rams 49ers +8.5 Over 43.5
6 Eagles vs. Giants Giants +7.5 Over 41.5
7 Steelers vs. Bengals Bengals +5.5 Over 44.5
8 Vikings vs. Chargers Chargers -3.5 Over 44.5
9 Ravens vs. Dolphins Ravens -7.5 Under 51.5
10 Raiders vs. Broncos Raiders -9.5 Under 41.5
11 Jets vs. Patriots Patriots -12.5 Under 42.5
12 Bills vs. Texans Bills -5.5 Under 44.5

🗓️ Thursday Night Football 2025 schedule

Opening Thursday Night Football odds for the 2025 regular season are via DraftKings.

Week Matchup Opening spread Opening Over/Under
14 (Dec. 4) Cowboys vs. Lions Lions -6 48.5
15 (Dec. 11) Falcons vs. Buccaneers Buccaneers -5.5 47.5
16 (Dec. 18) Rams vs. Seahawks Rams -1.5 44.5
17 (Dec. 25 - Christmas) Broncos vs. Chiefs Chiefs -4.5 44.5

❓Thursday Night Football FAQs

Who is favored on Thursday Night Football this week?

The Detroit Lions are the 3.5-point home favorite over the Dallas Cowboys by the Thursday Night Football odds for Week 14.

How do I watch Thursday Night Football?

With the exception of the NFL 2025 regular-season opener Sept. 4 (which will air on NBC), all Thursday Night Football games can be found exclusively on Prime Video.

Who are the announcers on Thursday Night Football?

Al Michaels and Kirk Herbstreit are the Thursday Night Football broadcasters on Prime Video. Kaylee Hartung is the sideline reporter, and Terry McAulay is the rules analyst.

This broadcast crew has been together since 2022.

Which team will play the most Thursday Night Football games in 2025?

The Bills, Rams, Seahawks, Eagles, and Broncos will all play two Thursday Night Football games this season, though one of the Eagles' TNF broadcasts will actually be on Black Friday.

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