Packers vs. Lions AI Picks: Thanksgiving Predictions & Stat Projections Today

Our AI model projects the road underdogs to pull off the upset to kick off the NFL Thanksgiving slate.
Detroit Lions running back Jahmyr Gibbs (0) carries the ball against the Green Bay Packers as we offer our Packers vs. Lions AI predictions for NFL Thanksgiving.
Pictured: Detroit Lions running back Jahmyr Gibbs (0) carries the ball against the Green Bay Packers as we offer our Packers vs. Lions AI predictions for NFL Thanksgiving. Photo by Sarah Kloepping / USA TODAY NETWORK-Wisconsin via Imagn Images.
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NFL Thanksgiving kicks off in just over two hours when the Green Bay Packers (7-3-1) and Detroit Lions (7-4) face off at Ford Field in Detroit (1 p.m. ET, FOX), and our Packers vs. Lions AI predictions expect the road favorites to pull off the upset win over their NFC North rivals.

We've trained the latest ChatGPT model to offer its exact score prediction and projected stat leaders for both teams, as well as its best prop bet for Packers vs. Lions. You can catch the rest of our (human) expert picks today with our NFL Thanksgiving predictions.


🤖 Packers vs. Lions AI predictions: Thanksgiving 2025

See all of our NFL AI predictions for Week 13 with projected scores for every game.

Team 1Q 2Q 3Q 4Q Final
Packers 7 7 9 3 26
Lions 3 14 0 7 24

🔢 Packers projected stats

  • Passing leader: Jordan Love – 22/34, 235 yards, 1 TD, 1 INT
  • Rushing leader: Josh Jacobs – 17 rushes, 75 yards, 1 TD
  • Receiving leader: Christian Watson – 5 receptions, 69 yards, 1 TD

🔢 Lions projected stats

  • Passing leader: Jared Goff – 24/35, 249 yards, 2 TD, 1 INT
  • Rushing leader: Jahmyr Gibbs – 16 rushes, 82 yards; 3 receptions, 38 yards
  • Receiving leader: Amon-Ra St. Brown – 7 receptions, 87 yards

🔮 Packers vs. Lions prediction

Green Bay enters this matchup leaning heavily on its early-down efficiency. With Josh Jacobs providing consistent gains on the ground, Jordan Love is able to operate from structure and stay out of long-yardage traps. The Lions’ defense has been vulnerable this season to layered crossing concepts, and that’s where Christian Watson can build separation. Defensively, the Packers aren’t dominant, but they’ve been increasingly assignment-sound, allowing them to force Detroit into methodical drives rather than explosive sequences. That sets the stage for a tight, possession-driven game.

Detroit still finds success: Jahmyr Gibbs’ acceleration stresses Green Bay’s linebackers horizontally, and Jared Goff executes clean intermediate timing throws, particularly to Amon-Ra St. Brown. But red-zone execution remains inconsistent for the Lions, and a late third-quarter stall opens the door for the Packers. Love engineers a balanced fourth-quarter possession that ends in the go-ahead field goal, and Green Bay’s defense holds on the final drive. In a controlled, physical NFC North battle, the Packers’ situational efficiency leads to a narrow road win.

Score prediction: Packers 26, Lions 24

💡 More NFL predictions

Want more NFL betting advice? Check out all of our NFL analysis and NFL Week 13 predictions for every game this week.


💰 Best Packers vs. Lions player prop bet

See all of our experts' NFL picks based on the latest NFL odds.

⬆️ Jahmyr Gibbs Over 108.5 rushing + receiving yards

Gibbs is positioned for a high-volume game against a Packers defense that has struggled to string together stops against multi-dimensional backs. Green Bay’s linebackers have been inconsistent in space, and opponents have leaned heavily on motion and edge runs to stress their angles — exactly where Gibbs thrives. In our projection, he finishes with 82 rushing yards and 38 receiving yards (120 total) thanks to Detroit’s emphasis on early-down touches and schemed checkdowns to keep Green Bay’s pass rush from heating up Goff.

Even in a projected Lions loss, Gibbs profiles as one of the most stable volume plays in the game script. Detroit’s offense funnels through him whenever defenses sit back in two-high structures, and the Packers’ coverage tendencies often force underneath completions. With Gibbs clearing this line in four of his last five full games and Detroit increasingly tailoring its offense to his explosiveness, the Over on his combined yardage prop bet is the strongest match to both his role and our simulation.

Best bet: Jahmyr Gibbs Over 108.5 rushing + receiving yards (-114 via FanDuel)


🦃 Thanksgiving expert picks


📺 How to watch Packers vs. Lions: Thanksgiving 2025

  • Date: Thursday, Nov. 27
  • Kickoff: 1 p.m. ET
  • Location: Ford Field (Detroit)
  • TV: FOX

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