Monday Night Football Odds & Predictions Week 13: Giants vs. Patriots MNF Betting Lines
The NFL's Thanksgiving Week will conclude with the New England Patriots (10-2) hosting the New York Giants (2-10) as the 7.5-point betting favorite by the Monday Night Football odds. Kickoff at Gillette Stadium in Foxborough, Mass., will be at 8:15 p.m. ET on ESPN. The Over/Under in this lopsided matchup is set at 46.5 points.
Stay tuned to our NFL predictions for Week 13, as we'll cover Monday Night Football via picks against the spread, player props, same-game parlays, and first and anytime touchdown scorer predictions.
๐ MNF Week 13 odds: Giants vs. Patriots (-7.5)
The NFL odds for Week 13 have the Pats as the 7.5-point home betting favorite amid quarterback uncertainty for New York early in the week. Though Jameis Winston impressed for the Giants last week with a couple of highlight-reel plays, the line would like move in their favor if Dart is deemed able to return.
Our Brenden Schaeffer is backing Giants +7.5 with that expectation in his early Giants vs. Patriots prediction.
Live Monday Night Football odds
Our NFL odds update in real time and show the best line/odds for either side of the spread, Over/Under, and moneyline:
๐ฎ Monday Night Football predictions Week 13
Here are our expert NFL predictions for Monday Night Football this week between the Giants and Patriots, as part of our Week 13 NFL picks:
NYG +7.5 (-115) via Brenden Schaeffer: "The Giants are 6-3 ATS since benching Russell Wilson as the starter."
๐ Monday Night Football betting results
Here are the results of the spread and Over/Under from every completed Monday Night Football game this season:
| Week | Matchup | Spread | Over/Under |
|---|---|---|---|
| 1 | Vikings vs. Bears | Vikings +1.5 | O43.5 |
| 2 | Buccaneers vs. Texas | Buccaneers +2.5 | U42.5 |
| 2 | Chargers vs. Raiders | Chargers -3.5 | U46.5 |
| 3 | Lions vs. Ravens | Lions +4.5 | O53.5 |
| 4 | Jets vs. Dolphins | Dolphins -2.5 | O43.5 |
| 4 | Bengals vs. Broncos | Broncos -7.5 | U44.5 |
| 5 | Chiefs vs. Jaguars | Jaguars +3.5 | O45.5 |
| 6 | Bills vs. Falcons | Falcons +3.5 | U49.5 |
| 7 | Buccaneers vs. Lions | Lions -6.5 | U54.5 |
| 7 | Texans vs. Seahawks | Seahawks -3.5 | O41.5 |
| 8 | Commanders vs. Chiefs | Chiefs -11.5 | U48.5 |
| 9 | Cardinals vs. Cowboys | Cardinals +3.5 | U53.5 |
| 10 | Eagles vs. Packers | Eagles +1.5 | U44.5 |
| 11 | Cowboys vs. Raiders | Cowboys -3.5 | O48.5 |
| 12 | Panthers vs. 49ers | 49ers -7.5 | U49.5 |
๐๏ธ Monday Night Football 2025 schedule
Opening Monday Night Football NFL odds for the 2025 season regular season are via DraftKings.
| Week | Matcup | Opening spread | Opening Over/Under |
|---|---|---|---|
| 13 (Dec. 1) | Giants vs. Patriots | Patriots -3 | 42.5 |
| 14 (Dec. 8) | Eagles vs. Chargers | Eagles -2.5 | 45.5 |
| 15 (Dec. 15) | Dolphins vs. Steelers | Steelers -2.5 | 44.5 |
| 16 (Dec. 22) | 49ers vs. Colts | 49ers -3 | 46.5 |
| 17 (Dec. 29) | Rams vs. Falcons | Rams -3 | 46.5 |
Don't miss our lists of the best NFL parlay betting sites and top NFL prop betting sites!
โMonday Night Football FAQs
Who is favored on Monday Night Football this week?
The New England Patriots are the 7.5-point betting favorite against the New York Giants by the Monday Night Football odds for Week 13.
How do I watch Monday Night Football?
Monday Night Football is broadcast on ESPN with some doubleheaders appearing on ABC.
Who are the announcers on Monday Night Football?
Joe Buck and Troy Aikman are the current commentators for Monday Night Football on ESPN. Laura Rutledge and Lisa Salters are the sideline reporters, and Russell Yurk is the rules analyst on the broadcast.
Who will make the most Monday Night Football appearances in 2025?
No team will make more than two appearances on Monday Night Football season.
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